SBSI drills W1 (F) Flashcards

GI and rheum Deck is full

1
Q

Clinical uses of misoprostol

A
  1. induce labor or abortion
  2. prevent NSAID induced ulcers
  3. maintain PDA patency
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2
Q

PPI S/E

A
  1. c diff
  2. aspiration pneumonia
  3. osteoporosis
    * *PPI raise pH of stomach –> bacterial growth–>infec
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3
Q

Bismuth s/e

A

black tongue

black stool

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4
Q

Octreotide uses

A
  1. bleeding esophageal varices
  2. acromegally
  3. carcinoid tumor
  4. VIPoma
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5
Q

3 drugs for gastroparesis

A
  1. metoclopramide (Reglan)
  2. erythromycin
  3. cisapride
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6
Q

Cimetidine s/e

A

antiadrenergic = gynecomastia, impotence, decr libido

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7
Q

Which H2 blockers affect renal function?

A
  1. cimetidine

2. ranitidine

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8
Q

Meds that cause pill induced esophagitis

A
NSAIDs B.A-T.H + KCl
    NSAIDs
    Bisphosphonates
    ABX 
        Tetracyclines
    HAART
    KCl
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9
Q

Uses of scopalamine

A

prevent motion sickness

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10
Q

metoclopramide s/e

A
  1. diarrhea
  2. Parkinson-like symptoms
  3. hyperprolactinemia
  4. tardive dyskinesia
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11
Q

In addition to metaclopramide, what other medications cause parkinsonian symptoms?

A

antipsycotics (especially risperidone)

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12
Q

Uses of ondansetron?

A

anti-emetic in chemo pts and post-sx pts

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13
Q

Hepatic encephalopathy tx (3)

A
  1. lactulose (poop it out)
  2. Rifaxamin
  3. Neomycin
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14
Q

Sulfasalazine s/e

A

oligospermia

(a man w/ little sperm sulfas)

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15
Q

Sulfasalazine uses

A
  1. IBD

2. RA

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16
Q

prior to starting infliximab what must be done?

A

r/o TB (PPD, quantiferon gold, CXR)

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17
Q

Use of Orlistat

A

weightloss (poop out the fat)

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18
Q

OD on ____ –> hyporeflexia, weakness, hypotension, resp depression, and drowsiness?

A

Mg

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19
Q

How to treat Mg toxicity?

A

Cagluconate

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20
Q

CaCarbonate (Tums) OD –>

A
  1. hypercalcemia

2. mild alkaline syndrome (low Phos, low K, high Ca)

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21
Q

Loperamide (imodium) use

A

anti-diarrheal

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22
Q

MCC lower GI bleed age>50

A

diverticulosis

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23
Q

ABD Xray depicts free air under the diaphragm. NS?

A

Surgery

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24
Q

Dx modality for cholecystitis when U/S is equivocal?

A

HIDA scan

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25
Palpate painful RUQ and pt's inspiration arrests. What is this called and what does it indicate?
positive murphy sign indicates cholecystitis
26
MCC SBO w/o h/o prior sx
hernia
27
Attend church picnic and several hours later present with diarrhea. what bug?
s. aureus (potato salad)
28
Consumption of raw sea food --> diarrhea. what bug?
vibrio vulnificus | Hep A
29
Camping and drank untreated H20 --> diarrhea. what bug?
giardia lamblia
30
Consumption of leftover fried rice --> diarrhea. what bug?
B. Cerius
31
What 2 bugs cause pseudo-appendicitis?
1. yersinia | 2. campylobacter
32
MC bacterial cause of diarrhea
campylobacter
33
recent ABX --> diarrhea. what bug?
c diff
34
30 yo M with UC presents w/ fatigue, jaundice, pruritis. Dx?
PSC
35
IBD tx
Obtain remission/ flares = steroids (prednisone, budesonide) Maintain remission = mesalamine, sulfasalazine Refractory disease = immunologics (infliximab, ustekinumab)
36
Mallory weiss vs borehaaves
mallory weiss = partial tears. weekend warriors. bleeding = self-limited. Borehaaves = full thickness tears. career vomitors. bleeding requires intervention.
37
Watery diarrhea s/p meal + h/o fistulas. Dx?
Chron's dz
38
Charcot's triad? | Reyaud's pentad?
``` Triad = 1. Fever 2. Jaundice 3. RUQ pain Pentad = Traid + 4. hypotension 5. AMS ```
39
Tx for acute GI bleed
ABC's 1. intubate to protect airway if needed 2. obtain access (2 large bore IVs) --> IVF +/- RBC transfusions
40
4 yo presents w/ oliguria, petechiae, jaundice s/p bloody diarrhea. dx?
HUS (2/2 e coli 057:H7 or shigella infec)
41
Causes of drug induced hepatitis
1. TB txs (RIP, rifampin, isoniazid, pyrazinamide) 2. acetominophen 3. tetracyclines
42
POOP on abd exam. Dx?
Mesenteric ischemia/ischemic cholitis
43
acute pancreatitis tx
NPO, IVF, pain control
44
Does R or L sided colon ca present w/ occult blood loss anemia?
Right sided | --Left sided presents with frank blood
45
Pt presents w/ watery diarrhea + dehydration + m. weakness + flushing. Dx?
VIPoma
46
VIPoma tx
- Octreotide | - Replace fluids and electrolytes as needed
47
What should you give for post exposure pertussis ppx?
erythromycin, azithromycin (macrolides)
48
Giving erythromycin and/or azithromycin early in infancy increases risk of what?
projectile vomiting 2/2 pyloric stenosis
49
Asprin s/e
renal toxicity --> interstitial nephritis gastric ulcers bleeding tinnitus Reyes synd (kids. this is why kids get tylenol)
50
Indomethacin uses
- close PDA - analgesia - anti-inflammatory
51
Celebrex/ celecoxib s/e
- incr risk thrombosis - sulfa allergy * *Safe for use in pts w/ gastritis b/c MOA = cox2 inhib only
52
Bisphosphonate uses
-osteoporosis -paget's dz of the bone -hypercalcemia (MOA inhib osteoclast activity)
53
Bisphosphonate s/e
- osteonecrosis of the jaw | - pill induced esophagitis
54
What is the reversal agent for tylenol overdose?
n-acetylcysteine
55
Longterm gout tx =
- allopurinol - probenacid - febuxostat
56
Acute gout tx =
- NSAIDs - STEROIDS **1st/only option in CKD pts** - colchicine
57
Allopurinol is used leukemia and lymphoma to prevent what?
tumor lysis syndrome
58
How to prevent tumor lysis syndrome (2)?
- allopurinol | - rasburicase
59
What are the uses of enteracept?
- RA - ankylosing spondylitis - psoriasis
60
What are infliximab and adalimumab used for?
- RA - ankylosing spondylitis - psoriasis - IBD
61
Teraperitide use
osteoporosis
62
methotrexate uses
- IBD - cancer (leukemia, lymphoma, choriocarcinoma) - SLE - RA - abortion (given w/ misoprostol)
63
methotrexate s/e = ? | hint: think Ms and Fs
- Folate def - aplastic anemia - abortion - teratogenic - Myelosuppression - Macrovesicular Fatty liver changes - pulm Fibrosis
64
How to tx the myelosuppression caused by methotrexate use?
Leucovorin
65
5-fluorouracil (5-FU) uses
1. pancreatic ca 2. colorectal ca 3. basal cell ca (topical form)
66
5-fluorouracil (5-FU) s/e
myelosuppression
67
How to tx myelosuppression caused by 5-FU?
uridien (pyrimidine analog) and thymidine
68
hydorxychloroquine use
- antimalarial - sickle cell anemia - arthritis - SLE
69
hydroxychloroquine s/e
retinal toxicity
70
cyclophosphamide s/e
hemorrhagic cystitis
71
What is the tx for hemorragic cystitis 2/2 tx w/ cyclophosphamide?
MESNA
72
What drugs induce SLE?
``` alpha-SHIPPE ALPHA-methyldopa Sulfa drugs Hydralazine Isoniazid Procainamide Phenytoin Etanercept ```
73
Pt presents w/ back pain that incr w/ standing/walking and decr w/ sitting/hyperflexing hips. Dx = ?
spinal stenosis
74
Pt presents w/ hip and back pain that incr w/ rest and decr w/ exercise. Dx = ?
Ankylosing spondylitis
75
What test diagnoses ankylosing spondylitis?
xray SI joint + lumbar spine --> shows sacroiliitis + bamboo spine