SBSI drills W1 (F) Flashcards

GI and rheum Deck is full

1
Q

Clinical uses of misoprostol

A
  1. induce labor or abortion
  2. prevent NSAID induced ulcers
  3. maintain PDA patency
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2
Q

PPI S/E

A
  1. c diff
  2. aspiration pneumonia
  3. osteoporosis
    * *PPI raise pH of stomach –> bacterial growth–>infec
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3
Q

Bismuth s/e

A

black tongue

black stool

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4
Q

Octreotide uses

A
  1. bleeding esophageal varices
  2. acromegally
  3. carcinoid tumor
  4. VIPoma
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5
Q

3 drugs for gastroparesis

A
  1. metoclopramide (Reglan)
  2. erythromycin
  3. cisapride
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6
Q

Cimetidine s/e

A

antiadrenergic = gynecomastia, impotence, decr libido

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7
Q

Which H2 blockers affect renal function?

A
  1. cimetidine

2. ranitidine

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8
Q

Meds that cause pill induced esophagitis

A
NSAIDs B.A-T.H + KCl
    NSAIDs
    Bisphosphonates
    ABX 
        Tetracyclines
    HAART
    KCl
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9
Q

Uses of scopalamine

A

prevent motion sickness

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10
Q

metoclopramide s/e

A
  1. diarrhea
  2. Parkinson-like symptoms
  3. hyperprolactinemia
  4. tardive dyskinesia
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11
Q

In addition to metaclopramide, what other medications cause parkinsonian symptoms?

A

antipsycotics (especially risperidone)

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12
Q

Uses of ondansetron?

A

anti-emetic in chemo pts and post-sx pts

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13
Q

Hepatic encephalopathy tx (3)

A
  1. lactulose (poop it out)
  2. Rifaxamin
  3. Neomycin
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14
Q

Sulfasalazine s/e

A

oligospermia

(a man w/ little sperm sulfas)

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15
Q

Sulfasalazine uses

A
  1. IBD

2. RA

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16
Q

prior to starting infliximab what must be done?

A

r/o TB (PPD, quantiferon gold, CXR)

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17
Q

Use of Orlistat

A

weightloss (poop out the fat)

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18
Q

OD on ____ –> hyporeflexia, weakness, hypotension, resp depression, and drowsiness?

A

Mg

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19
Q

How to treat Mg toxicity?

A

Cagluconate

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20
Q

CaCarbonate (Tums) OD –>

A
  1. hypercalcemia

2. mild alkaline syndrome (low Phos, low K, high Ca)

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21
Q

Loperamide (imodium) use

A

anti-diarrheal

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22
Q

MCC lower GI bleed age>50

A

diverticulosis

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23
Q

ABD Xray depicts free air under the diaphragm. NS?

A

Surgery

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24
Q

Dx modality for cholecystitis when U/S is equivocal?

A

HIDA scan

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25
Q

Palpate painful RUQ and pt’s inspiration arrests. What is this called and what does it indicate?

A

positive murphy sign indicates cholecystitis

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26
Q

MCC SBO w/o h/o prior sx

A

hernia

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27
Q

Attend church picnic and several hours later present with diarrhea. what bug?

A

s. aureus (potato salad)

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28
Q

Consumption of raw sea food –> diarrhea. what bug?

A

vibrio vulnificus

Hep A

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29
Q

Camping and drank untreated H20 –> diarrhea. what bug?

A

giardia lamblia

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30
Q

Consumption of leftover fried rice –> diarrhea. what bug?

A

B. Cerius

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31
Q

What 2 bugs cause pseudo-appendicitis?

A
  1. yersinia

2. campylobacter

32
Q

MC bacterial cause of diarrhea

A

campylobacter

33
Q

recent ABX –> diarrhea. what bug?

A

c diff

34
Q

30 yo M with UC presents w/ fatigue, jaundice, pruritis. Dx?

A

PSC

35
Q

IBD tx

A

Obtain remission/ flares = steroids (prednisone, budesonide)
Maintain remission = mesalamine, sulfasalazine
Refractory disease = immunologics (infliximab, ustekinumab)

36
Q

Mallory weiss vs borehaaves

A

mallory weiss = partial tears. weekend warriors. bleeding = self-limited.

Borehaaves = full thickness tears. career vomitors. bleeding requires intervention.

37
Q

Watery diarrhea s/p meal + h/o fistulas. Dx?

A

Chron’s dz

38
Q

Charcot’s triad?

Reyaud’s pentad?

A
Triad = 1. Fever    2. Jaundice     3. RUQ pain
Pentad = Traid  +  4. hypotension    5. AMS
39
Q

Tx for acute GI bleed

A

ABC’s

  1. intubate to protect airway if needed
  2. obtain access (2 large bore IVs) –> IVF +/- RBC transfusions
40
Q

4 yo presents w/ oliguria, petechiae, jaundice s/p bloody diarrhea. dx?

A

HUS (2/2 e coli 057:H7 or shigella infec)

41
Q

Causes of drug induced hepatitis

A
  1. TB txs (RIP, rifampin, isoniazid, pyrazinamide)
  2. acetominophen
  3. tetracyclines
42
Q

POOP on abd exam. Dx?

A

Mesenteric ischemia/ischemic cholitis

43
Q

acute pancreatitis tx

A

NPO, IVF, pain control

44
Q

Does R or L sided colon ca present w/ occult blood loss anemia?

A

Right sided

–Left sided presents with frank blood

45
Q

Pt presents w/ watery diarrhea + dehydration + m. weakness + flushing. Dx?

A

VIPoma

46
Q

VIPoma tx

A
  • Octreotide

- Replace fluids and electrolytes as needed

47
Q

What should you give for post exposure pertussis ppx?

A

erythromycin, azithromycin (macrolides)

48
Q

Giving erythromycin and/or azithromycin early in infancy increases risk of what?

A

projectile vomiting 2/2 pyloric stenosis

49
Q

Asprin s/e

A

renal toxicity –> interstitial nephritis
gastric ulcers
bleeding
tinnitus
Reyes synd (kids. this is why kids get tylenol)

50
Q

Indomethacin uses

A
  • close PDA
  • analgesia
  • anti-inflammatory
51
Q

Celebrex/ celecoxib s/e

A
  • incr risk thrombosis
  • sulfa allergy
  • *Safe for use in pts w/ gastritis b/c MOA = cox2 inhib only
52
Q

Bisphosphonate uses

A

-osteoporosis
-paget’s dz of the bone
-hypercalcemia
(MOA inhib osteoclast activity)

53
Q

Bisphosphonate s/e

A
  • osteonecrosis of the jaw

- pill induced esophagitis

54
Q

What is the reversal agent for tylenol overdose?

A

n-acetylcysteine

55
Q

Longterm gout tx =

A
  • allopurinol
  • probenacid
  • febuxostat
56
Q

Acute gout tx =

A
  • NSAIDs
  • STEROIDS 1st/only option in CKD pts
  • colchicine
57
Q

Allopurinol is used leukemia and lymphoma to prevent what?

A

tumor lysis syndrome

58
Q

How to prevent tumor lysis syndrome (2)?

A
  • allopurinol

- rasburicase

59
Q

What are the uses of enteracept?

A
  • RA
  • ankylosing spondylitis
  • psoriasis
60
Q

What are infliximab and adalimumab used for?

A
  • RA
  • ankylosing spondylitis
  • psoriasis
  • IBD
61
Q

Teraperitide use

A

osteoporosis

62
Q

methotrexate uses

A
  • IBD
  • cancer (leukemia, lymphoma, choriocarcinoma)
  • SLE
  • RA
  • abortion (given w/ misoprostol)
63
Q

methotrexate s/e = ?

hint: think Ms and Fs

A
  • Folate def
  • aplastic anemia
  • abortion
  • teratogenic
  • Myelosuppression
  • Macrovesicular Fatty liver changes
  • pulm Fibrosis
64
Q

How to tx the myelosuppression caused by methotrexate use?

A

Leucovorin

65
Q

5-fluorouracil (5-FU) uses

A
  1. pancreatic ca
  2. colorectal ca
  3. basal cell ca (topical form)
66
Q

5-fluorouracil (5-FU) s/e

A

myelosuppression

67
Q

How to tx myelosuppression caused by 5-FU?

A

uridien (pyrimidine analog) and thymidine

68
Q

hydorxychloroquine use

A
  • antimalarial
  • sickle cell anemia
  • arthritis
  • SLE
69
Q

hydroxychloroquine s/e

A

retinal toxicity

70
Q

cyclophosphamide s/e

A

hemorrhagic cystitis

71
Q

What is the tx for hemorragic cystitis 2/2 tx w/ cyclophosphamide?

A

MESNA

72
Q

What drugs induce SLE?

A
alpha-SHIPPE
    ALPHA-methyldopa
    Sulfa drugs
    Hydralazine
    Isoniazid
    Procainamide
    Phenytoin
    Etanercept
73
Q

Pt presents w/ back pain that incr w/ standing/walking and decr w/ sitting/hyperflexing hips. Dx = ?

A

spinal stenosis

74
Q

Pt presents w/ hip and back pain that incr w/ rest and decr w/ exercise. Dx = ?

A

Ankylosing spondylitis

75
Q

What test diagnoses ankylosing spondylitis?

A

xray SI joint + lumbar spine –> shows sacroiliitis + bamboo spine