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Oral Pathology > Salivary Gland Disease > Flashcards

Salivary Gland Disease Flashcards

1
Q

AKA Mucus Extravasation Phenomenon what is a Spillage of mucin into the soft tissues due to rupture of a salivary gland duct, usually caused by trauma called?

A

Mucocele

*Usually in younger adults and children on lower lip FOM or anterior ventral tongue (minor salivary glands)

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2
Q

Mucoceles in floor of mouth, usually lateral to the midline

that are typically associated with rupture of the sublingual gland duct are called what?

A

Ranula

*Marsupialization entails removal of the roof of the lesion making a pseudo-duct

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3
Q

AKA Mucus Retention Cyst, what are epithelium-lined cavity that arises from salivary gland tissue called?

A

Salivary Duct Cyst

*Can be bluish in color

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4
Q

Where are the 4 most common places for a Salivary duct cyst?

A

1) parotid gland
2) FOM
3) buccal mucosa
3) lips

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5
Q

AKA Salivary Stone what is a calcification in the salivary duct called?

A

Sialolith (Sialolithiasis)

*often the submandibular gland because it is long and curvy

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6
Q

Inflammation of salivary glands is called?

A

Sialadenitis

*Can be an infection or non-infectious cause

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7
Q

What virus causes mumps (Epidemic Parotitis)?

A

Paramyxovirus

*Complication of Epididymoorchitis, oophoritis or mastitis

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8
Q

A swelling of the parotid or submandibular gland after general anesthesia is called?

A

Anesthesia mumps

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9
Q

Mainly in the parotid gland, what hypertrophic condition of the acini results in Non-inflammatory asymptomatic salivary gland enlargement?

A

Sialadenosis (Sialosis)

*Usually bilateral

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10
Q

What are three underlying systemic conditions that can lead to Sialadenosis?

A

1-Endocrine disorders
2-Malnutrition
3-Drugs

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11
Q

What occurs in minor glands, often on hard or soft palate

and results in localized, sessile painless swelling that mimics a neoplasm?

A

Adenomatoid Hyperplasia of the Minor Salivary Glands

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12
Q

Locally destructive inflammatory condition of the salivary glands that mimics malignancy clinically often due to dental injections is called?

A

Necrotizing Sialometaplasia

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13
Q

Swelling and eversion of the lower lip as a result of hypertrophy and inflammation of the minor salivary glands is called?

A

Chelitis Glandularis

*Associated with actinic cheilitis. Weeping mucopurulent secretions

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14
Q

Excessive Salivation is called?

A

Sialorrhea

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15
Q

What are three possible complications of xerostomia?

A

1-Candidiasis
2-Prone to cervical and root caries
3-Alteration of taste (metallic)

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16
Q

What is another name for the autoimmune disease sjogrens Syndrome?

A

Sicca Syndrome

*mainly affects salivary and lacrimal glands. May have bilateral swelling of parotid

17
Q

What are the 3 criteria, of which 2 of 3 must be met, to diagnose sjogrens?

A

1-Positive serum tests (4 different tests)
2-Ocular staining score of more than 3
3-Presence of focal lymphocytic sialadenitis with a focus score more than 1 (labial salivary gland biopsy)

18
Q

What are the 4 Serum tests used to test for sjogrens syndrome?

A

1-Anti SSA
2-Anti SSB
3-RF
4-ANA

19
Q

What are 2 examples of sialogauges that may be prescribed to treat sjogrens?

A
  • Pilocarpine (salagen)

- Cevimeline (evoxac)

20
Q

What condition increased the risk for lymphoma by 40x’s?

A

Sjogrens Syndrome

*Marginal zone lymphoma (MALT lymphoma)

21
Q

What are the most common sites for Salivary neoplasms from most to least?

A

1-Parotid gland
2-Minor glands (of these, palate is most likely site)
3-submandibular
4-sublingual

22
Q

What two major salivary gland neoplasm sites are more likely to be benign than malignant?

A

1-Parotid (70% benign)
2-Submandibular (60% benign)

*Sublingual is only 30% benign

23
Q

Which two minor salivary gland neoplasm sites are benign half the time and malignant half the time?

A

1-Palate
2-Cheek

*in general minor glands are 50/50

24
Q

Which minor salivary gland neoplasm site is more likely to be benign?

A

Upper lip (80% benign)

25
Q

What 3 minor salivary gland neoplasms are more likely to be malignant?

A

1-Lower lip (60% malignant)
2-Tongue (85% malignant)
3-Retromolar pad (90% malignant)

26
Q

What is most common benign neoplasm?

A

Pleomorphic adenoma

27
Q

What is most common malignant neoplasm?

A

Mucoepidermoid carcinoma

28
Q

What are the 4 kinds of benign Salivary Gland Neoplasms?

A

1-Canalicular adenoma
2-Pleomorphic adenoma
3-Warthin tumor (papillary cystadenoma lymphomatosum)
4-Oncocytoma

29
Q

What type of benign salivary gland neoplasm is a monomorphic adenoma that is most commonly on the upper lip in patients over 60??

A

Canalicular adenoma

*Pleomorphic adenoma are found more commonly on the upper lip in patients under 50

30
Q

Which neoplasm is a mixture of ductal and myoepithelial cells and is the most common salivary neoplasm?

A

Pleomorphic Adenoma (Benign Mixed Tumor)

*tumor is encapsulated

31
Q

Almost exclusively in parotid gland what is the second most common benign parotid tumor which may occur bilaterally?

A

Warthin’s Tumor (Papillary Cystadenoma Lymphomatosum)

*Smokers have an eightfold risk

32
Q

What are 5 Malignant Salivary neoplasms?

A 
1-Mucoepidermoid carcinoma
2-Acinic cell adenocarcinoma
3-Adenoid cystic carcinoma
4-Polymorphous low-grade adenocarcinoma (terminal duct adenocarcinoma)
5-Malignant mixed tumor
33
Q

What is the most common malignant salivary neoplasm and most commonly affects the parotid gland?

A

Mucoepidermoid Carcinoma

*Minor glands are second most common site, on palate

34
Q

An Ectopic salivary gland tissue that was developmentally entrapped within jaw
can cause what?

A

Intraosseous (Central) Mucoepidermoid Carcinoma

35
Q

Which low-grade malignant neoplasm shows serous acini differentiation and is the second most common malignant neoplasm?

A

Acinic Cell Adenocarcinoma

*Parotid is most common site, then minor glands followed by submand

36
Q

Which malignant salivary gland tumor is the most common of the submandibular gland?

A

Adenoid Cystic Carcinoma

*Associated pain from tumor wrapping around nerve

37
Q

Which malignant salivary gland neoplasm almost exclusively occurs in minor glands?

A

Polymorphous Low-grade Adenocarcinoma (Terminal Duct Carcinoma)

*Associated pain from tumor wrapping around nerve

38
Q

Which Malignant neoplasm is most commonly in major glands and may be present for years before rapid growth of transformed epithelial cells?

A

Malignant Mixed tumor

39
Q

What are two other names for Malignant mixed tumor?

A

1-Carcinoma ex pleomorphic adenoma

2- Carcinosarcoma

Oral Pathology (18 decks)

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