Odontogenic Cysts and Tumors Flashcards
What is the definition of an Odontogenic cyst?
Pathologic cavity lined by odontogenic epithelium (dental lamina) and filled with fluid or semisolid material
What are 3 odontogenic tumors of epithelial origin?
1-Ameloblastoma
2-Adenomatoid Odontogenic Tumor (AOT)
3-Calcifying Epithelial Odontogenic Tumor (CEOT)
What are 4 mixed odontogenic tumors?
1-Ameloblastic Fibroma
2-Ameloblastic Fibro-odontoma
3-Ameloblastic Fibrosarcoma
4-Odontoma
What are 4 Ectomesenchyme odontogenic tumors?
1-Central Odontogenic Fibroma (COF)
2-Peripheral Odontogenic Fibroma
3-Odontogenic Myxoma
4-Cementoblastoma
A cyst that originates by separation of the follicle from around the crown of an unerupted tooth attaching at the CEJ is called?
Dentigerous cyst
*most commonly Mandibular 3rd molars. Stratified squamous epithelial lining
What is the soft tissue analogue of a dentigerous cyst?
Eruption Cyst
*soft, translucent gingival swelling overlying the crown of an erupting tooth
Arising from the dental lamina, what has a 30% recurrence rate, is associated with a syndrome, and is also called a keratocystic odontogenic tumor (KOT)?
Odontogenic Keratocyst (OKC)
*involves an unerupted tooth 1/3 of the time
In what direction do odontogenic keratocysts tend to grow?
Anterior-Posterior direction
*doesnt cause bone expansion
What is the differential for a multilocular radiolucency?
1-Central Giant Cell Granuloma
2-Ameloblastoma
3-Odontogenic Keratocyst
4-Dentigerous cyst (IF impacted tooth involvement)
A tooth in the inferior border of the orbit is most likely what?
Odontogenic keratocyst
What are the 4 histological characteristics of Odontogenic Keratocysts?
1-Thin, friable wall
2-6-8 cells thick
3-Basal cell layer is palisading and hyperchromatic
4-wavy or “corrugated” parakeratin
What syndrome is due to the PTCH gene on chromosome 9?
Gorlin Syndrome/ Nevoid Basal Cell Carcinoma Syndrome
*know both names
Gorlin Syndrome/ Nevoid Basal Cell Carcinoma Syndrome is characterized by what 4 main things?
1-Multiple basal cell carcinomas (BCCAs)
2-Odontogenic keratocysts
3-Calcification of the falx cerebri
4-Rib anomalies (splayed or bifid ribs)
What odontogenic cysts with orthokeratinized lining and NO basal palisading is most common in the posterior mandible that looks like a dentigerous cyst?
Orthokeratinized Odontogenic Cyst (OOC)
*2% recurrence
What is the soft tissue counterpart to the lateral periodontal cyst, is derived from rests of serres with a predilection for the mandibular canine and premolar area?
Gingival Cyst of the Adult
*Typically facial gingiva around 5 mm
Which developmental odontogenic cyst typically occurs along the lateral root surface, arise from dental lamina and is the intrabony counterpart of the gingival cyst of the adult?
Lateral Periodontal Cyst
How do Lateral periodontal cysts appear radiographically?
Polycystic (multilocular) termed botryoid (“Grapelike”)
AKA gorlin cyst, what has Ghost cells histologically that can calcify?
Calcifying Odontogenic Cyst (COC)
Which developmental cyst with glandular and/or salivary gland features has a predilection for anterior mandible and recur 30% of the time?
Glandular odontogenic Cyst (GOC)
What characteristically develops on the buccal aspect of the mandibular first permanent molar, pushes tooth lingually and occurs during the eruption process?
Buccal Bifurcation Cyst
*Average age 10
What rare condition mimics odontogenic cysts except for having irregular and ragged margins, usually seen in older patients and arise within bone?
Odontogenic carcinoma
What is the most common clinically significant odontogenic tumor, is of odontogenic epithelial origin and usually happens in the 3rd-7th decade?
Ameloblastoma
*usually in molar-ascending rams area
What are the three types of ameloblastoma?
1-Conventional solid or multicystic – 85%
2-Unicystic – 15%
3-Peripheral – 1%
What are two ways the buccal and lingual cortical expansion are described on a radiograph?
1-“Soap bubble” – when the RL loculations are large
2-“Honeycombed” – when the loculations are small
