Allergies and Immunologic Disease Flashcards
A common oral lesions involving fungiform or filiform papilla are called what?
Transient Lingual Papillitis
What are the 3 patterns of Transient Lingual Papillitis?
1-Localized
2-Generalized
3-Diffuse, papulokeratotic variant (like a callus version)
What is Recurrent Aphthous Ulcerations (RAU) also known as?
Recurrent aphthous stomatitis
In a normal patient, where do Recurrent Apthous ulcers occur?
Movable mucosa
What are the 3 clinical variations of Recurrent Apthous ulcers?
1-Minor (85%)
2-Major (10%)
3-Herpetiform (5%)
Which variation of Recurrent Apthous ulcers occurs in childhood on moveable mucosa and are 3-10 mm in size?
Minor
*heal in 7-14 days, no scarring, fewest recurrences
Which variation of Recurrent Apthous ulcers occurs in adolescents, are associated with suttons disease, and are 1-3 cm?
Major
*heal in 2-6 wks, possible scarring
Which variation of Recurrent Apthous ulcers occurs in adults, have up to 100 ulcerations, and are 1-3 mm mainly on moveable mucosa?
Hepetiform
*heal in 7-10 days, no scarring, most frequent recurrence
What is typically prescribed for recurrent aphthous ulcers?
topical corticosteroid (clobetasol proprionate)
Ocular inflammation, genital ulcers and skin lesions typically in Turkish, Japanese or eastern mediterraneans is called what?
Behcet’s Syndrome
*joint pain is also a common complaint
Which Multisystem granulomatous disorder of unknown cause happens more often in African americans, typically have an abnormal chest x-ray with skin lesions?
Sarcoidosis
*Involve lungs, lymph nodes, skin, eyes, salivary glands
What are the two types of skin lesions involved with sacradosis?
1-Lupus pernio (Chronic, purple, indurated lesions on H&N)
2-Erythema nodosum (Scattered, nonspecific, tender, red nodules on lower legs)
What are two different syndromes associated with sarcoidosis?
1-Lofgren’s syndrome
2-Heerfordt’s syndrome
What 3 things make up Lofgren’s syndrome?
1-Erythema nodosum
2-Bilateral hilar lymphadenopathy
3-Arthralgia
What 4 things make up Heerfordt’s syndrome?
1-Parotid enlargement
2-Inflammation of eye
3-Facial paralysis
4-Fever
What 3 things are used to diagnose Sarcoidosis?
1-Elevated serum angiotensin-converting enzyme levels
2-Chest XRAY
3-Kveim test – no longer used
What condition most commonly involves the lips as non-tender persistent swelling?
Orofacial Granulomatosis
What 3 things make up Melkersson-Rosenthal syndrome?
1-Cheilitis granulomatosa (swollen lip)
2-Facial paralysis
3-Fissured tongue
What 3 things are typical of classic Wegener’s granulomatosis?
1-Necrotizing granulomatous lesions of respiratory tract
2-necrotizing glomerulonephritis
3-systemic vasculitis of small arteries and veins
What oral lesion is a characteristic manifestation of Wegener’s Syndrome?
Strawberry gingivitis
How is Wegner’s Syndrome diagnosed?
Indirect immunofluorescence detects presence of antineutrophil cytoplasm antibodies (ANCA)
Which two types of Antineutrophil Cytoplasm Antibodies are detected for when diagnosing Wegener’s syndrome?
1-Perinuclear (p-ANCA)
2-Cytoplasmic (c-ANCA) (most useful)
Large, red gingiva that may superficially slough due to flavoring is most likely what?
Contact Stomatitis from Cinnamon
AKA Quincke’s disease, what condition is diffuse edematous swelling of the soft tissues with no pain, but itching and erythema may be present?
Angioedema
*Most commonly caused by histamine release from mast cell degranulation
Angioedema with diffuse involvement of the head and neck is likely caused by what?
Angiotensin-converting enzyme (ACE) inhibitors such as the “prils” for Hypertension
