Saladin Ch25: The Digestive System Flashcards
What are 3 alternate names for the digestive system/tract?
Alimentary, enteron, and gastrointestinal
What is the length of the GI tract in a living person and cadaver?
5m/16ft and 9m/30ft
What is the name of the tissue covering the digestive organs?
peritoneum
What is the process of chemical digestion that breaks down carbs, fats, and protein?
hydrolysis
What two muscles define the oral cavity?
buccinator and orbicularis oris
What is an alternate name for the oral cavity?
buccal cavity
What is the space between the gums and the lips?
vestibule
What is the connection between the upper lip and gums?
superior labial frenulum
What are the involutions of the hard palate?
Friction ridges
What is the connection for the tongue on the inferior side?
lingual frenulum
What are the two salivary duct orifices?
Sublingual and submandibular
What is the connection between the lower lip and gums?
inferior labial frenulum
What type of tissue covers the tongue?
non-keratinized stratified squamous epithelium
What are the 3 types of lingual papillae?
Filliform, fungiform, and vallate
What is the alternate name for “taste”?
gustation
What is the nerve that innervates the anterior 2/3rd of the tongue?
facial (VII)
What is the nerve that innervates the posterior 1/3rd of the tongue?
glossopharyngeal (IX)
What are the bones that constitute the hard palate?
maxilla and palatine bones
What is the alternate name for “teeth”?
dentition
What is the term that describes varying sizes of teeth?
heterodont
What is the term that describes mammals who have two sets of teeth during a lifetime?
diphyodont
What is the term for the socket in which a tooth sits?
alveolus
What is the term that describes mammals whose teeth sit in sockets?
thecodont
What is the type of join that holds teeth in the alveolus?
gomphosis
What is the alternate name for the gum?
gingiva
What is the space where the tooth and gum meet?
gingival sulcus
What is the hard yellowish tissue that makes up the majority of the tooth?
dentin
What is the covering of the tooth above the gum?
enamel
What is the covering of the tooth below the gum?
cementum
What are two areas of tooth that contains arteries, veins, nerves, and loose connective tissue?
Pulp cavity and root canal
What is the pore through which nerves and vessels enter and exit the tooth?
apical foramen
What is the connective tissue that lines the alveolus and penetrates the cavity and tooth to hold it in place?
periodontal ligament
What are the 3 sets of salivary glands?
parotid, submandibular, sublingual
What is the component of saliva that breaks down starch?
salivary amylase
What is the component of saliva that breaks down lipids?
lingual lipase
What is the antibacterial enzyme found in saliva and what is its function?
IgA; it inhibits bacterial growth
What are the electrolytes found in saliva?
Na, K, Cl, HCO3
What muscle type is the pharynx composed of?
striated skeletal muscle
What is the opening in the diaphragm through which the esophagus passes?
esophageal hiatus
What are the 4 layers of the esophageal wall?
mucosa (inner), submucosa, muscularis externa, and serosa
What are the 3 layers of the mucosa?
stratified squamous epithelia, lamina propria, muscularis mucosae
What are the two muscle layers of the muscularis externa and what type of muscle are they?
inner circular, outer longitudinal, both are smooth muscle
What muscle types make up the length of the esophagus?
upper 1/3rd is skeletal, lower 1/3rd is smooth
What are the two parasympathetic nerve plexuses of the enteric nervous system?
submucosal (meissner) and myenteric (auerbach)
What is an alternate name for swallowing?
deglutition
What is the region of the brain that controls swallowing reflex?
medulla oblongata and pons
What is the term for food mixed with gastric secretions?
chyme
What are the actions of swallowing that are voluntary?
mouth closes, then tongue presses against the palate
What are the actions of swallowing that are involuntary?
sensory receptors raise the soft palate and uvula, the larynx raises against the epiglottis, the glottis closes, constrictors move bolus to esophagus, and peristalsis takes over
What are the 4 regions of the stomach?
Cardiac, fundic, body, and pyloric
What type of cell makes up the mucosa of the stomach wall?
simple columnar epithelium
What is the turnover rate of mucosa of the stomach wall?
3-6 days
What is the composition of musclaris external of the stomach wall?
longitudinal, circular, and oblique smooth muscle
What amount of gastric juice is produced by the gastric glands each day?
2-3 L
What type of cells produce mucus in the stomach?
mucous cells
What type of cells produce IF and HCL in the stomach?
parietal cells
What is the enzyme produced by parietal cells that aids in the production of HCL in the stomach?
carbonic anhydrase (CAH)
What are the enzymes activated by HCL?
pepsin and lipase
What ion conversion occurs due to HCL?
ferric iron (Fe3+) to ferrous iron (Fe2+)
What type of cells produce pepsinogen in the stomach?
chief cells
What is the active form of pepsinogen?
pepsin
What are the enteroendocrine cells in the stomach and what hormone do they secrete?
G cells, secrete gastrin
What are the ridges in the stomach?
gastric rugae
What is the ANS innervation of the stomach?
PS = Vagus; S = celiac ganglion
What is the path of blood supply to the stomach?
celiac artery –> gastric artery
What are the 3 hormones secreted by the duodendum?
secretin, cholecystokinin, glucose-dependent insulinotropic peptide
What are the 3 phases of gastric activity?
cephalic, gastric, and intestinal
What nerve is active during cephalic gastric activity phase?
vagus
What are the hormones secreted during the gastric phase of gastric activity?
gastrin and histamine
What are the reflexes during the gastric phase of gastric activity?
myenteric and vagovagal
What hormones are secreted during the intestinal phase of gastric activity?
CCK, secretin, and GIP
What are the two regions of the liver?
right hypochondriac and epigastric
What are the 3 sources of blood supply?
1: abdominal aorta –> celiac –> hepatic a.
2: small intestine –> hepatic portal vein
3: hepatic veins –> inferior vena cava
What is the subunit for the liver?
lobules
What provides the central drainage of a lobule?
central vein
What 3 vessels compose the hepatic triad?
hepatic portal vein, hepatic artery, and bile ductile
What are the cells in the liver that produce bile that is sent to the bile ductule?
hepatocytes
What structure stores and concentrates bile?
gall bladder
What is the network of ducts that dump into the small intestine?
right and left hepatic ducts –> common hepatic –> joins cystic duct –> joins pancreatic duct –> hepatopancreatic ampulla –> small intestine
What are the cell types that make up pancreatic islets?
alpha and beta cells
What hormone is secreted by alpha cells?
glucagon
What hormone is secreted by beta cells?
insulin
What is the neural reflex that stimulates pancreatic juice production?
parasympathetic
What is the neural reflex that inhibits pancreatic juice production?
sympathetic
What is the hormone secreted by the duodendum upon arrival of fats?
cholecytoskinin
What is the effect of CCK?
bile and pancreatic enzyme release
What is the hormone secreted by duodendum upon arrival of acid?
secretin
What is the effect of secretin?
ductal cells release HCO3-
What are the 3 zymogens produced by acinar cells?
trypsinogen, chymotrypsinogen, procarboxypeptidase
What enzyme is produced by brush border cells?
enterokinase
What is the action of enterokinase?
trypsinogen is converted to trypsin
What are the 2 actions of trypsin?
chymotrypsinogen is converted to chymotrypsin; procarboxypeptidase is converted to carboxypeptidase
What 4 active enzymes are produced by acinar cells?
pancreatic lipase, pancreatic amylase, ribonuclease, and deoxyribonuclease
What are the cells that release HCO3- in the pancreas?
ductal cells
What are the finger-like projections of the small intestine?
villi
What are the folds/projections on the surface of cells?
microvilli
What are the 3 regions of the small intestine from start to finish?
duodenum, jejunum, ileum
What is an alternate name for microvilli?
brush border
What are the depressions in the small intestine surface?
intestinal crypts
What is the cell type found in intestinal crypts?
paneth cells
What is the enzyme produced by paneth cells?
lysozyme
What is an alternate name for lymphatic nodules found in the ileum?
peyer’s patcehs
What is the enzyme in the mouth that breaks carbs into oligosaccharides?
salivary amylase
What is the enzyme that breaks oligosaccharides into disaccharides?
pancreatic amylase
What is the name of the enzyme group that breaks down proteins?
proteases
What protease is found in the stomach?
pepsin
What are the 3 brush border enzymes found in the small intestine?
carboxypeptidase, aminopeptidase, and dipeptidase
What is the name of the enzyme group that breaks down lipids?
lipases
What lipases require gastic acid activation?
lingual lipase
What is the organ where emulsification of lipids occurs?
small intestine
What is the name of the enzyme group that breaks down nucleic acids?
nucleases
What are the two nucleases found in pancreatic juice?
ribonuclease and deoxyribonuclease
What are the products of nuclease action?
nucleosidases (ribose, deoxyribose) and phosphatases (phosphate ions)
What are the 4 fat soluble vitamins?
A, D, E, K
What is the pouch-like region at the beginning of the large intestine?
cecum
What are the pouches on the midline of the large intestine?
hastrum
What are the longitudinal muscles around the outside of the large intestine?
taenia coli
What type of cell makes up the endothelium of the large intestine?
dimple columnar epithelium
What are the functions of intestinal flora?
break down cellulose, produce B and K vitamins, and produce gas
What are the functions of large intestine?
reabsorb water and electrolytes
What is the oral portion of alimentary canal during embryo development?
stomodaeum
What is the anal portion of the alimentary canal during embryo development?
proctodaeum