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PATHOLOGY > Rosai Chapter 5 - Mandible and Maxilla > Flashcards

Rosai Chapter 5 - Mandible and Maxilla Flashcards

1
Q

Major extracellular components of the tooth (3)

A

“DEC”

  • Dentin
  • Enamel
  • Cementum
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2
Q

Major extracellular component of the tooth:

radially striated appearance caused by the presence of innumerable minute canals (the dentinal tubules) containing cytoplasmic processes from the odontoblasts

A

-Dentin

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3
Q

Major extracellular component of the tooth:

Consists of thin rods or prisms that on cross section are separated by concentric lines (lines of Retzius)

A

-Enamel

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4
Q

Major extracellular component of the tooth:

Very similar to bone in physicochemical characteristics and is indeed regarded as a special type of bone

A

-Cementum

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5
Q

Nests of cells in odontogenic epithelium (2)

A
  • rests of Serres

- rests of Malassez

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6
Q

Nests of cells in odontogenic epithelium:

-located in alveolar mucosa

A

rests of Serres

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7
Q

Nests of cells in odontogenic epithelium

-resulting from breakup of the dental lamina

A

rests of Serres

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8
Q

Nests of cells in odontogenic epithelium

-embedded within the periodontium

A

-rests of Malassez

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9
Q

other name of Pulse Granulomas (4):

A
  • Hyaline ring-like structures
  • Lentil granuloma
  • Oral vegetable granuloma
  • Giant cell hyaline angiopathy
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10
Q

What disease entity?

Main microscopic finding:

-Acute suppurative inflammation and resorptive scalloping of margins of non-vital bone within a large portion of maxilla and mandible

A

-Acute and Subacute Osteomyelitis

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11
Q

component of SAPHO Syndrome (5):

A
  • Synovitis
  • Acne
  • Pustulosis
  • Hyperostosis
  • Osteitis
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12
Q

True or False (re: SAPHO syndrome):

  1. There is non-suppurative osteomyelitis of the jaw
  2. Antibiotic therapy is NOT effective
A

1 & 2. True

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13
Q

other name of Simple Bone Cyst (3):

A
  • Traumatic cyst
  • Solitary cyst
  • Hemorrhagic cyst
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14
Q

What histologic feature is common on these jaw lesions?

  • Central giant cell lesion (granuloma)
  • Cherubism
  • Giant cell tumor (Osteoclastoma)
  • Fibro-osseous lesions
  • the bone lesion of Hyperparathyroidism (brown tumor)
  • Hereditary hyperparathyroidism-jaw tumor syndrome
  • Aneurysmal bone cyst
A

-Large numbers of Osteoclast-like multinucleated giant cells

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15
Q

Most common lesion of the jaw that feature large numbers of Osteoclast-like multinucleated giant cells

A

-Central giant cell lesion (granuloma)

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16
Q

other name of Central giant cell granuloma

A

Reparative giant cell granuloma

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17
Q

other name of Ossifying fibroma (2):

A
  • Cementifying fibroma

- Cemento-ossifying fibroma

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18
Q

Types of Osseous dysplasia (3)

A
  • Periapical
  • Focal
  • Florid
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19
Q

Type of Osseous dysplasia:

-Found in middle-aged black women

A

-Periapical

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20
Q

Type of Osseous dysplasia:

-Apex of a single tooth, usually a mandibular incisor

A

-Periapical

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21
Q

Type of Osseous dysplasia:

-Multiple teeth in the posterior mandible

A

-Focal

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22
Q

Type of Osseous dysplasia:

-Multiple jaw quadrants

A

-Florid

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23
Q

Type of Osseous dysplasia:

-Symptomatic

A

-Florid

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24
Q

Which entity?

Microscopically, the most typical feature:
-Presence of curvilinear trabecular (“ginger root” pattern) or irregularly-shaped cementum-like masses set within a vascular stroma

A

Osseous dysplasia

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25
Q

Two major categories of epithelial cysts

A
  • Odontogenic cysts

- Fissural (Non-odontogenic) cysts

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26
Q

Category of Epithelial Cyst

-arise from the odontogenic epithelium

A

-Odontogenic cyst

27
Q

Category of Epithelial Cyst

-located within the jaw (rarely in the adjacent soft tissue)

A

-Odontogenic cyst

28
Q

Category of Epithelial Cyst

-arise from epithelial inclusions within soft or body portions of the region that lack the embryologic and tooth-forming heritage of odontogenic epithelium

A

-Fissural (Non-odontogenic) cyst

29
Q

Category of Epithelial Cyst

-along embryologic fissure lines

A

-Fissural (Non-odontogenic) cyst

30
Q

Category of Epithelial Cyst

-outside of the jaw bones

A

-Fissural (Non-odontogenic) cyst

31
Q

Most frequent location of Adenomatoid Odontogenic Tumor

A

Anterior maxilla

32
Q

Other name of Adenomatoid Odontogenic Tumor

A

Adenoameloblastoma

33
Q

Other name of Calcifying Epithelial Odontogenic Tumor

A

Pindborg tumor

34
Q

Ameloblastic Fibroma vs. Ameloblastoma

-Cellular myxoid connective tissue stroma - Present

A

Ameloblastic Fibroma

35
Q

Ameloblastic Fibroma vs. Ameloblastoma

-Cellular myxoid connective tissue stroma - Absent

A

Ameloblastoma

36
Q

Most common odontogenic tumor

A

Odontoma

37
Q

Other name of Odontoameloblastoma (2):

A
  • Ameloblastic Odontoma

- Odontoblastoma

38
Q

Odontoameloblastoma vs. Ameloblastoma

-Dental hard tissues - Present

A

Odontoameloblastoma

39
Q

Odontoameloblastoma vs. Ameloblastoma

-Dental hard tissues - Absent

A

Ameloblastoma

40
Q

Positive IHCs of Myxoma cells in Odontogenic Myxoma (2)

A
  • Vimentin

- SMA

41
Q

Negative IHC of Myxoma cells in Odontogenic Myxoma

A

-S100

42
Q

Intramuscular myxoma vs. Odontogenic myxoma

-Activating mutations in the GNAS1 gene - Present

A

Intramuscular myxoma

43
Q

Intramuscular myxoma vs. Odontogenic myxoma

-Activating mutations in the GNAS1 gene - Absent

A

Odontogenic myxoma

44
Q

Most common of the epithelial odontogenic tumors

A

Ameloblastoma

45
Q

Two predominant patterns of ameloblastoma

A
  • Follicular

- Plexiform

46
Q

Positive IHCs of Ameloblastoma (2)

A
  • Cytokeratins (5, 14, 8, 18, and 19)

- Calretinin

47
Q

Cytokeratin IHC stain that is positive in Ameloblastoma cells in stellate reticulum-like areas (3)

A
  • CK8
  • CK18
  • CK19
48
Q

Ameloblastoma vs. Keratocyst

-Calretinin - Positive

A

Ameloblastoma

49
Q

Ameloblastoma vs. Keratocyst

-Calretinin - Negative

A

Keratocyst

50
Q

Positive or Negative

IHC of Granular cell Ameloblastoma:

-Keratin

A

Positive

51
Q

Positive or Negative

IHC of Granular cell Ameloblastoma:

-CD68

A

Positive

52
Q

S100

A

Negative

53
Q

Type/s of Unicystic Ameloblastoma

-Ameloblastous epithelium confine to the cyst lining

A

-Luminal and Intraluminal types

54
Q

Type/s of Unicystic Ameloblastoma

-Ameloblastous epithelium extends into the underlying stroma

A

-Mural type

55
Q

Type/s of Unicystic Ameloblastoma

Tx: Simple enucleation

A

-Luminal and Intraluminal types

56
Q

Type/s of Unicystic Ameloblastoma

Tx: treated like conventional solid/multicystic ameloblastomas because they have recurrence risk

A

-Mural type

57
Q

Other name of ameloblastic fibrosarcoma (2)

A
  • Odontogenic sarcoma

- Odontogenic fibrosarcoma

58
Q

Other name of Melanotic neuroectodermal tumor of infancy (2)

A
  • Melanotic progonoma

- Retinal anlage tumor

59
Q

Most common location of Melanotic neuroectodermal tumor of infancy

A

Maxilla

60
Q

Positive IHCs of MNET of infancy

-in the Small neuroblastic cells (4):

A
  • NSE
  • CD57
  • Synaptophysin
  • GFAP
61
Q

Positive IHCs of MNET of infancy

-in the Epithelial cells (3)

A
  • CK
  • HMB45
  • Vimentin
62
Q

Most common primary malignant tumor of the jaw

A

Osteosarcoma

63
Q

Clue to the diagnosis of Tophaceous pseudogout (humoral Calcium Pyrophosphate Dehydrate Crystal Deposition Disease [CPDCDD])

A

-identification by polarized light of birefringent crystals associated with granulomatous reaction

PATHOLOGY (26 decks)

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