CP must knows Flashcards
Type of Deferral
Prospective donor is unable to donate blood for a limited period of time
Temporary deferral
Type of Deferral
Prospective donor is unable to donate blood for someone else for an unspecified period of time due to current regulatory requirements
Indefinite deferral
Type of Deferral
This donor would not be able to donate blood until the current requirement changes. These donors may be eligible to donate autologous blood
Indefinite deferral
Type of Deferral
Prospective donor will never be eligible to donate blood for someone else. These donors may be eligible to donate autologous blood
Permanent deferral
An allogeneic blood donor should weigh
at least 110 lbs (50 kg)
The minimum hemoglobin for a female whole blood donor
12.5 g/dL
The minimum hemoglobin for a male whole blood donor
13.0 g/dL
Persons who have had a blood transfusion are deferred for
12 months
owing to risk of exposure to hepatitis, HIV, or other viral diseases
The interval between whole blood donations
8 weeks or 56 days
The interval between plasmapheresis, plateletpheresis, or leukapheresis
at least 2 days
Attenuated live viral vaccines such as smallpox, measles, mumps, yellow fever, and influenza carry a _ deferral
2-week deferral
A blood donor that has a positive serologic test for syphilis is deferred for
12 months
An autologous donor must have a hemoglobin of at least _ g/dL and a hematocrit of at least _
Hgb - at least 11.0 g/dL
Hct - at least 33%
Males who have had sex with another male (MSM) in the past 12 months are deferred for
1 year
takes place in the operating room when 1 to 3 units of whole blood are collected and the patient’s volume is replaced with colloid or crystalloid, then reinfused during surgical procedure, starting with the first unit collected
Acute normovolemic hemodilution
Diseases which are required to be tested for in blood screening process (8)
- Hepatitis B
- Hepatitis C
- HIV
- HTLV
- Syphilis
- West Nile virus
- Trypanosoma cruzi
- Zika virus
Spin conditions
Red blood cells + plasma
5,000 × g, 5 minutes
Spin conditions
Red blood cells + platelet-rich plasma
2,000 × g, 3 minutes
Spin conditions
Harvesting platelets or cryoprecipitate from plasma
5,000 × g, 7 minutes
Crystalloid vs. Colloid
Intravascular retention - Poor
Crystalloid
Crystalloid vs. Colloid
Peripheral edema - Common
Crystalloid
Crystalloid vs. Colloid
Pulmonary edema - Possible
Both
Crystalloid vs. Colloid
Easily excreted - Yes
Crystalloid
Crystalloid vs. Colloid
Allergic reactions - Absent
Crystalloid
Crystalloid vs. Colloid
Cost - Inexpensive
Crystalloid
Crystalloid vs. Colloid
Example - Ringer’s lactate solution
Crystalloid
Crystalloid vs. Colloid
Example - 7.5% normal saline
Crystalloid
Crystalloid vs. Colloid
Intravascular retention - Good
Colloid
Crystalloid vs. Colloid
Peripheral edema - Possible
Colloid
Crystalloid vs. Colloid
Easily excreted - No
Colloid
Crystalloid vs. Colloid
Allergic reactions - Rare
Colloid
Crystalloid vs. Colloid
Cost - Expensive
Colloid
Crystalloid vs. Colloid
Example - Albumin
Colloid
Crystalloid vs. Colloid
Example - Dextran
Colloid
Crystalloid vs. Colloid
Example - Hydroxyethyl starch
Colloid
Blood component
Major indication:
-Symptomatic anemia with large-volume deficit
Whole blood
Blood component
Mode of Action:
- Increases oxygen- carrying capacity
- Increases blood volume
Whole blood
Blood components (4)
NOT required to be ABO identical
- Red blood cells: leukocyte-reduced
- Platelets/apheresis platelets
- Platelets leukocytes-reduced/apheresis platelets leukocytes-reduced
- Cryoprecipitate pooled/ cryoprecipitated AHF
Blood component
Major indication
-Symptomatic anemia; red blood cell exchange transfusion
Red blood cells: RBCs (adenine-saline added), RBC pheresis
Blood component
Risks
-Same as whole blood category
Red blood cells: RBCs (adenine-saline added), RBC pheresis
Blood component
Mode of Action
Increases oxygen-carrying capacity
Red blood cells: RBCs (adenine-saline added), RBC pheresis
