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PATHOLOGY > Immunohistochemistry > Flashcards

Immunohistochemistry Flashcards

Location

1
Q

Clusters of Differentiation (CD)

A

Membranous

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2
Q

HER2/neu

A

Membranous

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3
Q

EGFR

A

Membranous

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4
Q

E-cadherin

A

Membranous

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5
Q

TTF-1

A

Nuclear

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6
Q

CDX2

A

Nuclear

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7
Q

Myogenin

A

Nuclear

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8
Q

WT1

A

Nuclear

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9
Q

p53

A

Nuclear

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10
Q

p63

A

Nuclear

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11
Q

Esterogen Receptor (ER)

A

Nuclear

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12
Q

Progesterone Receptor (PR)

A

Nuclear

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13
Q

Ki-67 / MIB1

A

Nuclear

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14
Q

Cytokeratins (CK)

A

Cytoplasmic

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15
Q

Desmin

A

Cytoplasmic

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16
Q

Vimentin

A

Cytoplasmic

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17
Q

Actin

A

Cytoplasmic

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18
Q

ACTH

A

Cytoplasmic

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19
Q

S100

A

Nuclear and Cytoplasmic

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20
Q

p16

A

Nuclear and Cytoplasmic

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21
Q

Calretinin

A

Nuclear and Cytoplasmic

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22
Q

AMACR / Racemase

A

Cytoplasmic granular (mitochondrial / peroxisomal)

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23
Q

Napsin A

A

Cytoplasmic granular (lysosomal)

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24
Q

HepPar1

A

Cytoplasmic granular (mitochondrial)

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25
Q

CD30 in classical Hodgkin Lymphoma

A

Cytoplasmic dot-like (golgi staining)

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26
Q

CD15 in classical Hodgkin Lymphoma

A

Cytoplasmic dot-like (golgi staining)

27
Q

Cytokeratins (CKs) in Neuroendocrine carcinomas

A

Cytoplasmic dot-like (perinuclear)

Punctate

28
Q

PAX8

A

Nuclear

29
Q

p40

A

Nuclear

30
Q

Ki-67 / MIB1 in Hyalinizing trabecular tumor/adenoma of thyroid

A

Membranous / Cytoplasmic

31
Q

GFAP

A

Cytoplasmic

32
Q

Neurofilament

A

Cytoplasmic

33
Q

HMB45

A

Cytoplasmic

34
Q

Melan-A

A

Cytoplasmic

35
Q

Trypsin

A

Cytoplasmic

36
Q

Beta-catenin (normal)

A

Membranous in Epithelial cells

Cytoplasmic in Stromal cells

37
Q

Beta-catenin in Desmoid-type Fibromatosis and some Colon CAs

A

Nuclear

38
Q

CD30 in Anaplastic Large cell Lymphoma

A

Cytoplasmic dot-like (golgi staining)

39
Q

CK20 in Merkel cell CA

A

Perinuclear dot-like (punctate)

40
Q

ATRX

A

Nuclear

41
Q

BCL2

A

Membranous and Cytoplasmic

42
Q

POSITIVE or NEGATIVE

BCL2 in Follicular lymphoma

A

Positive

43
Q

BCL2 in reactive follicles

A

Negative

44
Q

BCL10

A

Cytoplasmic

45
Q

Ber-EP4

A

Membranous

46
Q

Brachyury

A

Nuclear

47
Q

CA 19-9

A

Cytoplasmic

48
Q

h-Caldesmon

A

Cytoplasmic

49
Q

h-Caldesmon in Leiomyosarcoma

A

Positive

50
Q

POSITIVE or NEGATIVE

h-Caldesmon in myofibroblastic lesions such as fibromatosis

A

Negative

51
Q

CD1a

A

Membranous

52
Q

CD31

A

Membranous and Cytoplasmic

53
Q

CD34

A

Membranous and Cytoplasmic

54
Q

CD34 in DFSP vs. Dermatofibroma

A
  • DFSP+

- Dermatofibroma-

55
Q

CD56 / NCAM

A

Membranous

56
Q

CD68

A

Membranous and Cytoplasmic

57
Q

CD99 / MIC2 / O13

A

Membranous and Cytoplasmic

58
Q

CD138

A

Membranous

59
Q

CDK4

A

Nuclear

60
Q

CEA

A

Cytoplasmic

61
Q

Chromogranin A

A

Cytoplasmic (granular)

62
Q

c-Kit / CD117

A

Membranous and Cytoplasmic

63
Q

c-Kit/CD117 in Thymoma vs Thymic CA

A
  • Thymoma-

- Thymic CA+

PATHOLOGY (26 decks)

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