RNA Resp Viruses Flashcards

1
Q

4 Kinds of RNA Resp Viruses

A

Rhinoviruses
Orthomyxoviruses
Coronaviruses
Paramyxoviruses

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2
Q

Rhinovirus Two Kinds of Ags

A

Knob and pocket

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3
Q

Rhinovirus Most Common R Used

A

ICAM-1 of Ig Superfamily

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4
Q

3 Orthomyxoviruses and Type of Outbreak of Each

A

Influenza A (pandemics)
B (local epidemics)
C (not common)

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5
Q

Kind of Cell Orthomyxoviruses Infect

A

Mitotically active because needs to steal caps from nucleus

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6
Q

Original Antigenic Strain

A

Only ever make Abs to epitopes shared w/ first influenza you encountered

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7
Q

6 Things Named in Influenza Strain

A
Type
Host of Origin (nothing if human)
Geographic Origin
Strain Number
Year of Isolation
Agic Description
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8
Q

2 Neurological Complications with Influenza

A

Reye’s Syndrome - high mortality encephalopathy/fatty degeneration of liver in children/teens
Guillan Barre Syndrom - temporary paralysis from Ab attack on PNS

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9
Q

4 Antivirals for Influenza

A

Amantidine and rimantidine: early

Zanamivir and oseltamivir: end

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10
Q

2 Notable Outbreaks Caused by Coronaviruses

A

SARS and MERS

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11
Q

2 Subfamilies of Paramyxoviruses

A

Paramyxovirinae and pnemuovirinae

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12
Q

3 Genera in Paramyxovirinae

A

Paramyxovirus, rubulavirus, and morbillivirus

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13
Q

4 Differences bw Paramyxoviruses and Orthomyxoviruses

A

Paras are larger, have unsegmented DNA, form inclusion bodies in cytoplasm, and can lack N or both H and N

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14
Q

4 Diseases Caused by Paramyxoviruses

A

Measles
Mumps
Parainfluenza
Respiratory Syncytial Virus

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15
Q

Croup

A

Severe laryngotracheobronchitis in babies/toddlers caused by parainfluenza 1 and 2 with hoarseness and barking cough

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16
Q

Main Symptom of Mumps

A

Swelling of parotid gland only AFTER systemic infection

17
Q

5 Measles Symptoms

A
Rash/Koplik's spots
Conjunctivitis
Cough
Coryza
Photophobia
18
Q

Subacute sclerosing panencephalitis

A

Very fatal viral CNS infection caused by defective measles years after the disease

19
Q

Difference in Measles/Rubella Rashes

A

Measles starts on face and covers all torso/face to confluence
Rubella starts on torso and then spreads to concentrate on extremities (not confluent)

20
Q

Most Notable Congenital Rubella Finding

A

Cataracts in young children