Hepatitis Viruses

Question 1

Hepatitis A Notable Contagious Feature

Answer 1

Shedding begins with viremia, before immune response causes symptoms. So common to transmit before that (also spread by shellfish)

Question 2

2 Particles Seen under Microscope with BV

Answer 2

Dane particle - Actual virion in HBV

Long aggregates of HBV surface Ags

Question 3

Surface Ags in HBV

Answer 3

Has major, middle, and large forms. S Gene encodes major, S + something before encodes middle, etc

Question 4

3 Theories for HBV Oncogenesis (and which one is HCV oncogenesis)

Answer 4

Viral DNA inserts directly into growth gene
Viral DNA is transactivator of growth gene
Liver damage overstimulates regeneration/growth genes (HCV mech)

Question 5

HDV Notable Feature

Answer 5

Is viroid-like and requires HBV for coat. So needs HBV for any infection but it makes those more severe

Question 6

HEV 2 Notable Features

Answer 6

Far more severe in pregnant women, just like HAV in everything else