Retroviruses Flashcards
1
Q
3 Proteins in RV Capsid
A
Protease
Integrase
RT
2
Q
3 Genome Regions
A
gag, pol, and env, encoding for core, enzymes, and envelope, respectively
3
Q
Rous sarcoma virus
A
Oncovirus that keeps all 3 regions when it gets ONC
4
Q
HTLV-1 2 Diseases
A
Acute adult T cell lymphocytic leukemia (ATLL)
HTLV-1-associated myelopathy, a non oncogenic neurlogic disease
5
Q
HIV Binding/Membrane Entry
A
gp120 binds CD4, but it also has to bind and push over CXCR4 or CCR5 to get right up to membrane and insert gp41. So if a person has a mutation in these, they are resistant.
6
Q
2 Mechs gp120 Uses to Evade Immune System
A
Agic drift because in 1 host so long
Glycosylates self and can expose/hide different parts of itself
