Rivaroxaban Flashcards
1
Q
what is it and mechanism
A
DOAC (Direct Oral Anticoagulant)
inhibits factor 10a so no fibrin formation so stops coagulation cascade
2
Q
indications
A
treatment of DVT and PE
Prevention of the recurrence of DVT and PE
prevention of VTE in patients undergoing hip/ knee replacements
3
Q
contraindications
A
active bleeding
conditions at risk of bleeding e.g. malignant neoplasm
anti-phospholipid syndrome
4
Q
interactions
A
antifungals e.g. fluconazole
anticoagulants e.g. enoxaparin (heparin)
NSAIDs
SSRIs
Warfarin
5
Q
Side effects
A
anaemia (iron deficiency)
dizziness
headaches
skin reactions e.g. itch
