Enoxaparin Flashcards
1
Q
what is it and mechanism
A
Low Molecular Weight Heparin
prevents fibrinogen conversion into fibrin-> prevents coagulation cascade
2
Q
indications
A
prophylaxis of DVT/ PE- especially in surgical patients or acutely unwell
treatment of DVT in pregnant women (DOACs contraindicated)
treatment of DVT in people that are at low risk of recurrence
can be given in MI when undergoing a Primary PCI
3
Q
contraindications
A
History of heparin- induced thrombocytopenia (low platelets)
clinically significant bleeding e.g. peptic ulcer
4
Q
interactions
A
thrombolytics e.g. TPA
NSAIDs e.g. aspirin
systemic glucocorticoids e.g prednisolone
5
Q
side effects
A
increase in liver enzymes
haemorrhage thrombocytopenia allergic reaction headache urticaria (hives) and associated pruritus
