Aspirin Flashcards
1
Q
what is it and mechanism
A
Anti-platelet agent
NSAID
stops prostaglandin synthesis which prevents platelet aggregation and reduces inflammatory processes
2
Q
indications
A
secondary prophylaxis after an MI/ DVT/ PE
unstable angina/ NSTEMI
in acute cerebral TIA and stroke
3
Q
contraindications
A
nasal polyps associated with asthma
peptic ulcers
haemophilia
end of pregnancy
high dose methotrexate
4
Q
interactions
A
other NSAIDs
calcium channel blockers e.g. amlodipine
ototoxic medication egg, vancomycin
high dose methotrexate
5
Q
side effects
A
dyspepsia (stomach discomfort after eating)
increased bleeding tendencies
rhinitis
dyspnoea
Urticaria (hives)
