RICKETTSIA Flashcards
RICKETTSIA KEY FACTS
OBLIGATE INTRACELLULAR
CULTURED IN YOLK SAC OF EMBRYONATED EGGS OR IN SELECT TISSUE CULTURE CELL LINES
STAINED BY ROMANOWKSKY
VECTOR BORNE- SPREAD BY TICKS, FLEAS, LICE, MOSQUITO
ZOONOTIC
INTERMEDIATE BETWEEN VIRUSES AND BACTERIA
EMERGING AND RE-EMERGING DISEASES
OBLIGATE INTRACELLULAR
RICKETTSIA TARGETS WHAT
ENDOTHELIUM
CAUSES VASCULITIS
RESERVOIRS OF RICKETTSIA
SMALL MAMMALS AND RODENTS
TRANSMISSION OF RICKETTSIA
ARTHROPOD BITE OR INHALATION OF ARTHROPOD FECES
RICKETTSIA CAUSES WHAT
SPOTTED FEVER
THYPUS
R. RICKETTSIA CAUSES
ROCKY MOUNTAIN SPOTTED FEVER
TICK VECTOR- DERMACENTOR
HOSTS- HUMANS, DOGS
R FELIS CAUSES
FLEA-BORNE SPOTTED FEVER
CAT FLEAS (CTENOCEPHALOIDES)
HUMAN HOST
R. TYMPHI CAUSES
MURINE TYPHUS
RAT AND CAT FLEAS
XENOPSYLLA AND CTENOCEPHALOIDES
HOST-HUMANS
ROCKY MOUNTAIN SPOTTED FEVER
SLYVATIC CYCLE IN WILDLIFE IMPORTANT- SMALL MAMMALS AND RODENTS
RANGE OF INFECTION DEPENDS ON TICK DISTRIBUTION
ROCKY MOUNTIAIN SPOTTED FEVER, R RICKETTSIA VIRULENCE FACTORS
PHOSPHOLIPASE AND PROTEASE DAMAGE MEMBRANES OF ENDOTHELIUM
R RICKETTSIA REPLICATES WHERE
CYTOPLASM AND NUCLEUS OF HOST CELL
R. RICKETTSIA CAUSES ENDOTHELIAL DAMAGE THAT INITIATES
VASCULITIS, PLATELET ACTIVATION, DIC, NECROSIS
R. RICKETSSIA- ROCKY MOUNTAIN SPOTTED FEVER CLINICAL SIGNS
FEVER DEPRESSION ANOREXIA SUBCUTANEOUS EDEMA PETECHIA IN MUCOSA MYALGIA
CAT FLEA TYPHUS LIKE ILLNESS - SPOTTED FEVER
R FELIS
CATS ARE ASYMPTOMATIC
VETOR CTENOCEPHALOIDES FELIS
SYLVATIC CYCLE =OPOSSUMS
MURINE TYPHUS
CAUSED BY RICKETTSIA TYPHI VECTOR C. FELIS AND XENOPHYLLA
RESERVOIRS- RODENTS, CATS, OPOSSUMS
ENDEMIC TO S.CALIFORNIA AND TEXAS
TRANSMISSION SCRATCHING OF INFECTED FLEA FECES INTO A BITE WOUND
HUMANS
R. RICKETTSIA IN DOGS CAUSES
THROMBOCYTOPENIA
SEROLOGY***** (BUT CANT TELL BW/ THYPHUS GROUP)
TREATMENT OF RICKETTISIA
DOXYCYCLINE
TETRACYCLINE
ENROFLAXIN
CHLORAMPHENICOL
ANAPLASMATACEAE
ANAPLASMA
EHRLICHIA
NEORICKETTSIA
ANAPLASMATACEAE IS EXTRACELLULAR OR INTRACELLULAR
INTRACELLULAR IN LEUKOCYTES, ERYTHROCYTES, ENDOTHELIAL CELLS, PLATELETS
WHAT VECTORS FOR ANAPLASMATACEAE
NEORICKETTSIA- TREMATODE
ANAPLASMA AND EHRLICHIA - TICKS
RESERVOIRS FOR ANAPLASMATACEAE
WILDLIFE