MANNHEMIA Flashcards

1
Q

MANNHEMIA HEMOLYTICA IS ____

A

OBLIGATE SYMBIOTIC, FACULTATIVE PATHOGENIC IN RUMINANTS

WITH LOW ENVT RESISTANCE

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2
Q

MANNHEMIA HEMOLYTIC VIRULENCE FACTORS

A
LEUKOTOXIN- RTX FAMILY- HEMOLYSIS
TRANSFERRIN BINDING PROTEINS 
ENDOTOXINS-LPS
CAPSULE-ANTIPHAGOCYTOSIS 
FIMBRIAE
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3
Q

LEUKOTOXIN

A

LOW DOSE- OXIDATIVE METABOLISM OF NEUTROPHILS AND MACROPHAGES

HIGH DOSE- LYSIS OF PHAGOCYTES

ONLY EFFECTIVE IN SHEEP AND CATTLE

STRONGLY ANTIGENIC

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4
Q

WHERE IS M. HEMOLYTICA FOUND COMMENSALLY IN SHEEP?

A

NOSE AND TONSILS

ALL SEROTYPES

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5
Q

WHERE IS M HEMOLYTICA FOUND COMMENSALLY IN BOVIDS?

A

NASOPHARYNX AND TONSILS

SEROTYPES 1,2,6

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6
Q

BACTERIA BRONCHOPNEUMONIA IN CALVES

A

ENVT- REGROUPING ANIMALS (KINDERGARTEN FOR COWS)
VIRAL INF
BACTERIAL INF

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7
Q

WHAT DOES M HEMOLTYICA CAUSE

A
FIBRINOUS NECROTIC BRONCHO PNEUMONIA 
GENERAL SYMPTOMS- FEVER, ANOREXIA 
RESPIRATORY DISTRESS 
SEROFIBRINOUS PLEURITIS 
WELL DEFINED PNEUMONIA ZONES IN LUNGS
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8
Q

ENDOGENIC INFECTION

A

STRESS-> MULTIPLICATION IN NASOPHARYNX

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9
Q

EXOGENIC INFECTION

A

EXCRETION OF MH IN HIGH NUMBERS OTHER ANIMALS GET COLONIZED (AEROSOL, CLOSE CONTACT)

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10
Q

M HEMOLYTICA VACCINE SHOULD CONTAIN

A

LEUKOTOXIN, SURFACE ANTIGENS, TRANSFERRIN BINDING PROTEINS

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11
Q

IMMUNITY AGAINST M. HEMOLYTICA IS

A

MAINLY ANTIBODY MEDIATED

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12
Q

DIAGNOSIS M HEMOLYTICA

A

BACTERIAL CULTURE FROM LUNGS, BRONCHOALVEOLAR LAVAGE, NOSE

GET TO LAB FAST! LITTLE ENVT RESISTANCE

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13
Q

TREATMENT AND PREVENTION M HEMOLYTICA

A

VENTILATION, THERMOREGULATION, FEED LOWER ENERGY FEED- STOMACH FERMENTATION, VACCINATION, ABX

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14
Q

SHIPPING FEVER - WHAT 2 PATHOGENS

A

P. MULTOCIDA

M. HEMOLYTICA

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