BORDETELLA Flashcards
BORDETELLA BRONCHISEPTA IS
OBLIGATE SYMBIOTIC. FACULTATIVE PATHOGENIC.
BORDETELLA BROCHISEPTA HAS AFFINITY FOR
CILIATED RESPIRATORY EPITHELIUM
B. BRONCHISEPTA INFECTS WHAT AGE AND HOST
YOUNG PIGS.
WHAT DOES B. BRONCHISEPTA CAUSE. IN YOUNG. PIGS
NONPROGRESSIVE ATROPHIC RHINITIS, PNEUMONIC BORDETELLOSIS. (<1WK OLD PRIMARY;»_space;>1WK OLD SECONDARY INFECTION). PROGRESSIVE ATROPHIC RHINITIS (IN COMBINATION WITH PASTEURELLA MULTOCIDA)
BORDETELLA. VIRULENCE. FACTORS
ADHESINS (3). TOXINS. (4) LPS SIDEROPHORES LACTOFERRIN TRANSFERRIN BINDING PROTEIN. BVG REGULON BIOFILMS
WHAT IS BVG REGULON?
REGULATES EXPRESSION. BETWEEN VIRULENT AND NONVIRULENT. LOW TEMPERATURES = HIGHER VIRULENCE
WHAT ARE THE THREE ADHESION. FACTORS OF BORDETELLA
FILAMENTOUS HEMAGGLUTIN (MOST IMPORTANT- ATTACHMENT OF OUTER MEMBRANE TO MACROPHAGES), PERTACTIN, FIMBRIAE.
WHAT ARE THE 4 TOXINS OF. BORDETELLA AND THEIR FUNCTION.
HEMOLYSIN- PORE FORMING, INHIBITION OF NEUTROPHILS
DERMONECROTIC TOXIN- DAMAGE TO NASAL TISSUE AND OSTEOBLASTS
OSTEOTOXIN- TOXIC TO OSTEOBLASTS
TRACHEAL CYTOTOXIN- DAMAGES CILIATED RESPIRATORY EPITHELIUM
B. BRONCHISEPTA TRANSMISSION
AEROSOL, SOW TO PIGLET
PREDISPOSING FACTORS OF BORDETELLA BRONCHISEPTA
INFECTION PRESSURE, OVERCROWDING, STRESS, DUST, VENTILATION
HOW TO DIAGNOSE B. BRONCHISEPTA
CULTURE WITH BLOOD AGAR
PCR- SAMPLE. NOSE AND TONSILS
SYMPTOMS
HOW TO TREAT B. BRONCHISEPTA
HYGIENE, VAX SOW AND PIGLETS, ABX SULFONAMIDES
NONPRODUCTIVE ATROPHIC RHINITIS
DAMAGE NASAL MUCOSA
MUCOUS PRODUCTION
DERMONECROTIC TOXIN
PNEUMONIC BORDETELLOSIS
COUGHING, DYSAPNEA, NO FEVER, HIGH MORBIDITY
PURULENT. BRONCHIOLITIS AND ALVEOLITIS.
LESIONS IN LUNGS ARE DRY, BROWN.
<1WK OLD PRIMARY INF. >1WKOLD SECONDARY INF
PROGRESSIVE ATROPHIC RHINITIS
LOSS OF NASAL CONCHAE
IN COMBINATION WITH. PASTEURELLA MULTOCIDA
BB EFFECTS OSTEOBLASTS. PM EFFECTS OSTEOCLASTS
BB COLONIZES FIRST PM INFECTS SECOND
SEVERITY OF PROGRESSIVE ATROPHIC RHINITIS DEPENDS ON.
INFECTION PRESSURE
AGE AT COLONIZATION/INFECTION OF BB AND PM
DUST
VENTILATION
BORDETELLA BRONCHISEPTA IN DOGS
KENNEL COUGH
RHINTIS, TRACHEOBRONCHITIS, LARYNGITIS, PNEUMONIA AND PLEURITIS
IN DOGS WHEN IS BORDETELLA EXOGENIC? ENDOGENIC?
EXOGENIC- HIGH INFECTION PRESSURE
ENDOGENIC- FACULTATIVE, COLONIZES NOSE
SYMPTOMS OF. BORDETELLA IN DOGS
DRY COUGH, FEVER, ANOREXIA, LETHARGY
DIAGNOSIS OF. BORDETELLA IN DOGS
ISOLATION
CULTURE
BRONCHOALVEOLAR LAVAGE
TREATMENT OF BORDETELLA IN DOGS
SELF LIMITING DISEASE
HYGIENE AND DISINFECTION
GENERAL SYMPTOMS TREAT WITH TETRACYCLINE
VACCINE-
INACTIVATED GIVE AT 4-6WKS INTERFERES WITH MOTHER IGG
INTRANASAL GIVE AT 3WKS INTERFERES LESS, FAST PROTECTION
BORDETELLA BRONCHISEPTA IN KITTENS
NASAL DISCHARGE, LACRIMATION, SNEEZING, NON PRODUCTIVE DRY COUGH, ANOREXIA, DEATH
UPPER RESPIRATORY TRACT
TREATMENT BORDETELLA BRONCHISEPTA IN HORSES
TREATMENT
REST FOR THREE WEEKS FOR FULL RECOVERY
PREVENTION OF DUST, WET HAY, FEED ON FLOOR, REPLACE WITH ALFALFA
BORDETELLA BRONCISEPTA IN RABBITS
ALMOST ALL RABBIS ARE CARRIERS
NASAL DISCHARGE, SNEEZING, CONGESTION, TEARS, CONJUNCTIVITIS, BRONCHOPNEUMONIA WITH P. MULTOCIDA, BLINDNESS, OTITIS, ABSCESS
HOW TO TREAT BORDETELLA IN RABBITS
DO NOT USE CLINDAMYCIN OR LINCOMYCIN FATAL!!!!!!
USE TETRACYCLINE
IS BORDETELLA ZOONOTIC?
YES! IN IMMUNOCOMPROMISED HUMANS
BORDETELLA AVIUM
CORYZA
RHINOTRACHEITIS
WHAT POULTRY BIRD DOES BORDETELLA AVIUM EFFECT MOST?
TURKEYS
OLDER ANIMALS ARE CARRIERS
SEPARATE AGE GROUPS AS PREVENTION
SYMPTOMS OF B. AVIUM
CORYZA
STUNTED GROWTH, SEROMUCOUS NASAL DISCHARGE, SNEEZING, EYE, HEAD SHAKING, OPEN BEAK RESPIRATION, TRACHEAL RALES, DIRT ON WINGS
HOW IS CORYZA TRANSMITTED?
ENVIRONMENT
FLOOR AND BEDDING
CORYZA- TYPE OF INFECTIONS
ACUTE 1-6WEEKS OLD
CHRONIC OLDER ANIMALS ARE CARRIERS
