BORDETELLA Flashcards

1
Q

BORDETELLA BRONCHISEPTA IS

A

OBLIGATE SYMBIOTIC. FACULTATIVE PATHOGENIC.

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2
Q

BORDETELLA BROCHISEPTA HAS AFFINITY FOR

A

CILIATED RESPIRATORY EPITHELIUM

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3
Q

B. BRONCHISEPTA INFECTS WHAT AGE AND HOST

A

YOUNG PIGS.

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4
Q

WHAT DOES B. BRONCHISEPTA CAUSE. IN YOUNG. PIGS

A

NONPROGRESSIVE ATROPHIC RHINITIS, PNEUMONIC BORDETELLOSIS. (<1WK OLD PRIMARY;&raquo_space;>1WK OLD SECONDARY INFECTION). PROGRESSIVE ATROPHIC RHINITIS (IN COMBINATION WITH PASTEURELLA MULTOCIDA)

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5
Q

BORDETELLA. VIRULENCE. FACTORS

A

ADHESINS (3). TOXINS. (4) LPS SIDEROPHORES LACTOFERRIN TRANSFERRIN BINDING PROTEIN. BVG REGULON BIOFILMS

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6
Q

WHAT IS BVG REGULON?

A

REGULATES EXPRESSION. BETWEEN VIRULENT AND NONVIRULENT. LOW TEMPERATURES = HIGHER VIRULENCE

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7
Q

WHAT ARE THE THREE ADHESION. FACTORS OF BORDETELLA

A

FILAMENTOUS HEMAGGLUTIN (MOST IMPORTANT- ATTACHMENT OF OUTER MEMBRANE TO MACROPHAGES), PERTACTIN, FIMBRIAE.

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8
Q

WHAT ARE THE 4 TOXINS OF. BORDETELLA AND THEIR FUNCTION.

A

HEMOLYSIN- PORE FORMING, INHIBITION OF NEUTROPHILS
DERMONECROTIC TOXIN- DAMAGE TO NASAL TISSUE AND OSTEOBLASTS
OSTEOTOXIN- TOXIC TO OSTEOBLASTS
TRACHEAL CYTOTOXIN- DAMAGES CILIATED RESPIRATORY EPITHELIUM

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9
Q

B. BRONCHISEPTA TRANSMISSION

A

AEROSOL, SOW TO PIGLET

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10
Q

PREDISPOSING FACTORS OF BORDETELLA BRONCHISEPTA

A

INFECTION PRESSURE, OVERCROWDING, STRESS, DUST, VENTILATION

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11
Q

HOW TO DIAGNOSE B. BRONCHISEPTA

A

CULTURE WITH BLOOD AGAR
PCR- SAMPLE. NOSE AND TONSILS
SYMPTOMS

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12
Q

HOW TO TREAT B. BRONCHISEPTA

A

HYGIENE, VAX SOW AND PIGLETS, ABX SULFONAMIDES

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13
Q

NONPRODUCTIVE ATROPHIC RHINITIS

A

DAMAGE NASAL MUCOSA
MUCOUS PRODUCTION
DERMONECROTIC TOXIN

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14
Q

PNEUMONIC BORDETELLOSIS

A

COUGHING, DYSAPNEA, NO FEVER, HIGH MORBIDITY
PURULENT. BRONCHIOLITIS AND ALVEOLITIS.
LESIONS IN LUNGS ARE DRY, BROWN.

<1WK OLD PRIMARY INF. >1WKOLD SECONDARY INF

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15
Q

PROGRESSIVE ATROPHIC RHINITIS

A

LOSS OF NASAL CONCHAE

IN COMBINATION WITH. PASTEURELLA MULTOCIDA
BB EFFECTS OSTEOBLASTS. PM EFFECTS OSTEOCLASTS
BB COLONIZES FIRST PM INFECTS SECOND

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16
Q

SEVERITY OF PROGRESSIVE ATROPHIC RHINITIS DEPENDS ON.

A

INFECTION PRESSURE
AGE AT COLONIZATION/INFECTION OF BB AND PM
DUST
VENTILATION

17
Q

BORDETELLA BRONCHISEPTA IN DOGS

A

KENNEL COUGH

RHINTIS, TRACHEOBRONCHITIS, LARYNGITIS, PNEUMONIA AND PLEURITIS

18
Q

IN DOGS WHEN IS BORDETELLA EXOGENIC? ENDOGENIC?

A

EXOGENIC- HIGH INFECTION PRESSURE

ENDOGENIC- FACULTATIVE, COLONIZES NOSE

19
Q

SYMPTOMS OF. BORDETELLA IN DOGS

A

DRY COUGH, FEVER, ANOREXIA, LETHARGY

20
Q

DIAGNOSIS OF. BORDETELLA IN DOGS

A

ISOLATION
CULTURE
BRONCHOALVEOLAR LAVAGE

21
Q

TREATMENT OF BORDETELLA IN DOGS

A

SELF LIMITING DISEASE
HYGIENE AND DISINFECTION
GENERAL SYMPTOMS TREAT WITH TETRACYCLINE

VACCINE-
INACTIVATED GIVE AT 4-6WKS INTERFERES WITH MOTHER IGG
INTRANASAL GIVE AT 3WKS INTERFERES LESS, FAST PROTECTION

22
Q

BORDETELLA BRONCHISEPTA IN KITTENS

A

NASAL DISCHARGE, LACRIMATION, SNEEZING, NON PRODUCTIVE DRY COUGH, ANOREXIA, DEATH

UPPER RESPIRATORY TRACT

23
Q

TREATMENT BORDETELLA BRONCHISEPTA IN HORSES

A

TREATMENT
REST FOR THREE WEEKS FOR FULL RECOVERY

PREVENTION OF DUST, WET HAY, FEED ON FLOOR, REPLACE WITH ALFALFA

24
Q

BORDETELLA BRONCISEPTA IN RABBITS

A

ALMOST ALL RABBIS ARE CARRIERS

NASAL DISCHARGE, SNEEZING, CONGESTION, TEARS, CONJUNCTIVITIS, BRONCHOPNEUMONIA WITH P. MULTOCIDA, BLINDNESS, OTITIS, ABSCESS

25
Q

HOW TO TREAT BORDETELLA IN RABBITS

A

DO NOT USE CLINDAMYCIN OR LINCOMYCIN FATAL!!!!!!

USE TETRACYCLINE

26
Q

IS BORDETELLA ZOONOTIC?

A

YES! IN IMMUNOCOMPROMISED HUMANS

27
Q

BORDETELLA AVIUM

A

CORYZA

RHINOTRACHEITIS

28
Q

WHAT POULTRY BIRD DOES BORDETELLA AVIUM EFFECT MOST?

A

TURKEYS

OLDER ANIMALS ARE CARRIERS

SEPARATE AGE GROUPS AS PREVENTION

29
Q

SYMPTOMS OF B. AVIUM

A

CORYZA

STUNTED GROWTH, SEROMUCOUS NASAL DISCHARGE, SNEEZING, EYE, HEAD SHAKING, OPEN BEAK RESPIRATION, TRACHEAL RALES, DIRT ON WINGS

30
Q

HOW IS CORYZA TRANSMITTED?

A

ENVIRONMENT

FLOOR AND BEDDING

31
Q

CORYZA- TYPE OF INFECTIONS

A

ACUTE 1-6WEEKS OLD

CHRONIC OLDER ANIMALS ARE CARRIERS