CHLAMYDIA AND COXIELLA

Question 1

CHLAMYDIA IS _____

Answer 1

OBLIGATE INTRACELLULAR

DOESNT PRODUCE ITS OWN ATP

Question 2

Unique developmental cycle due to

Answer 2

Elementary body and reticulate body

Question 3

Elementary body

Answer 3

Small resistant form of bacteria, infects the host

Question 4

Reticulate body

Answer 4

Biologically active, only survives in the cell, related to replication within membrane bound cytoplasmic vacuole , non infectious

Question 5

Chlamydia colonizes what type of cell

Answer 5

Epithelial

Question 6

Chlamydia psittaci

Answer 6

Birds and humans

Genital , eye, lungs, internal organs

Question 7

Chlamydia pecorum

Answer 7

Cattle and sheep

Brain, eye, joints

Question 8

Chlamydophilia abortus

Answer 8

Sheep

Intestines, placenta, eyes

Question 9

Chlamydophilia felis

Answer 9

Cats and humans

Genitals, eye, joints, lungs

Question 10

T/F chlamydia is host specific

Answer 10

True

Question 11

How is chlamydia transmitted?

Answer 11

Direct animal to animal, aerosol, ingestion

Infected birds are a reservoir for infection

Question 12

Diagnosis of chlamydia

Answer 12

Cytology for EB inclusion bodies- fluorescence
Culture embryonated egg or tissue culture- obligate intracellular- most definitive diagnosis
Serology - determine exposure of a group of animals
PCR for diagnosis and detection of carriers

Question 13

Avian chlamydiosis

Answer 13

Chlamydia psittaci
REPORTABLE AND ZOONOTIC
Ocular secretions and feces of infected birds
Transmission- inhalation or ingestion
Stress increases shedding- captivity, transportation, egg laying, overcrowding
Treat with tetracycline

Question 14

Avian chlamydiosis clinical signs

Answer 14

Loss of condition, nasal and ocular discharge, diarrhea, respiratory distress, heptopenomegaly, airsacculitis, peritonitis

Question 15

Feline chlamydiosis

Answer 15

Cats less that 1yr old
Conjunctivitis and rhinitis
Shed from repro tract
Transmitted by conjunctival and nasal excretions, venereal

Question 16

Feline chlamydiosis

Answer 16

Conjunctival congestion, ocular discharge, edema, sneezing, nasal discharge, mucopurulent discharge= secondary inf with staphylococcus

Question 17

ENZOOTIC ABORTION OF EWES

Answer 17

C. ABORTUS 
ABORTION IN RUMINANTS 
INTRODUCTION TO CLEAN FLOCKS WHEN A REPLACEMENT ANIMAL ABORTS 
PLACENTA AND UTERINE BACTERIAL SHEDDING 
INFECTION OCCURS BY INGESTION

Question 18

CHLAMYDIA IN EWES TARGETS

Answer 18

TROPHOBLAST LAYER IN THE PLACENTA
CAUSES NECROTIC PLACENTITIS
ABORTION IN LATE PREGNANCY OR PREMATURE LAMBS
FERTILITY UNIMPAIRED NEXT CYCLE

Question 19

SPORADIC BOVINE ENCEPHALOMYELITIS

Answer 19

CHLAMYDIA PECORUM
YOUNG CATTLE
HIGH MORTALITY
HIGH FEVER, INCOORDINATION, DEPRESSION, EXCESSIVE SALIVATION, DIARRHEA, VASCULAR DAMAGE TO BRAIN, ANIMALS BECOME RECUMBENT

Question 20

COXIELLA BURNETII

Answer 20

OBLIGATE INTRACELLULAR - MONOCYTES, MACROPHAGES, TROPHOBLASTS
BSL3
AEROSOL BIOTERRORISM AGENT
VECTOR BORNE- TICKS
INFECTS RUMINANTS- MAY CAUSE PLACENTITIS AND ABORTION
ZOONOTIC

Question 21

COXIELLA EVASION OF IMMUNE SYSTEM

Answer 21

SURVIVAL IN PHAGOSOME LIKE COMPARTMENT

Question 22

COXIELLA FORMS

Answer 22

SMALL CELL VARIANT- SPORE LIKE FORM

LARGE CELL VARIANT- REPRODUCTIVE FORM

Question 23

COXIELLA BURNETTI CAUSES

Answer 23

Q FEVER

PLACENTITIS AND ABORTION IN RUMINANTS

Question 24

SHEEP AND GOATS ARE THE MAIN RESERVOIR FOR

Answer 24

COXIELLA BURNETTI

SHEDDING IN BIRTH PRODUCTS, MILK, URINE, FECES

Question 25

DIAGNOSIS OF COXIELLA

Answer 25

MODIFIED ZN STAIN 
IMMUNOFLUORESCENCE OF PLACENTA 
PCR MILK FECES PLACENTA VAGINAL SWABS (DETECTION OF SUBCLINICAL) 
CULTURE IN EGGS 
ELISA FOR HERD

Question 26

HERD DIAGNOSIS COXIELLA BURNETTI

Answer 26

PCR BULK MILK TANK

SEROLOGY FECES

Question 27

PREVENTION OF COXIELLA BURNETTI

Answer 27

SEGREGATION OF PARTURIENT ANIMALS