MYCOPLASMA Flashcards
MYCOPLASMA IN GENERAL
SMALLEST FREE LIVING BACTERIA
OBLIGATE INTRACELLULAR!!!!! CANNOT SURVIVE OUT OF HOST
NO CELL WALL- TRIPLE LAYER OUTER MEMBRANE
NOT SUSCEPTIBLE TO PENICILLIN
HOST SPECIFICITY
MYCOPLASMA IS COMMENSAL WHERE
MUCOUS MEMBRANES OF RESP AND REPRO
MYCOPLASMA HAS AFFINITY FOR WHAT
CILIATED RESPIRATORY EPITHELIUM
HOW TO DIFFERENTIATE MYCOPLASMA
HOST SPECIFICITY, CLONAL MORPHOLOGY, REQUIREMENT OF CHOLESTEROL FOR SURVIVAL, BIOCHEMICAL ACTIVITY
MYCOPLASMA MYCOIDES SUBSPECIES MYCOIDES
CONTAGIOUS BOVINE PLEUROPNEUMONIA
MYCOPLASMA BOVIS
MASTITIS, PNEUMONIA, ARTHRITIS IN CATTLE
MYCOPLASMA HYOPNEUMONIAE
ENZOONOTIC PNEUMONIA IN PIGS
MYCOPLASMA GALLISEPTUM
CHRONIC RESPIRATORY DISTRESS IN CHICKENS
MYCOPLASMA DIFFERENTIATION
CHOLESTEROL REQUIRED
DOES NOT PRODUCE UREASE
UMBONATE COLONIES OR FRIED EGG COLONIES
CAN STAIN WITH DIENES STAINS
DIAGNOSIS OF MYCOPLASMA
ISOLATION FROM CLINICAL SAMPLES
MUCOSAL SCRAPINGS, TRACHEAL EXUDATES, ASPIRATES, PNEUMONIC TISSUE, MILK AND FLUIDS FROM JOINTS AND BODY CAVITIES, SWABS FROM LESIONS(SPECIAL TRANSPORT MEDIUM)
IMMUNOLOGICAL TESTS
GROWTH INHIBITION TESTS
PCR
ELISA REQUIRED FOR INTERNATIONAL TRADE
FOR FLOCK OR HERD - RAPID PLATE AGGLUTINATION
PATHOGENICITY OF MYCOPLASMA
DOES NOT INVADE CELL
PRODUCTION OF H202 THAT CAUSES TOXIC DAMAGE
EVADE IMMUNE SYSTEM WITH VARIATION OF SURFACE PROTEINS AND BACTERIA COPIES HOST ANTIGENS (INTERFERES WITH HOST RECOGNITION)
PATHOGENIC PULMONARY MYCOPLASMAS ARE MITOGENIC FOR B AND T CELLS
CONTAGIOUS BOVINE PLEUROPNEUMONIA
SEVERE CONTAGIOUS- VERY PATHOGENIC TRANSMITTED BY AEROSOLS AND CARRIERS ENDEMIC AFRICA AND ASIA SEVERE SPORADIC - LESS SEVERE IN EXOTIC AREAS REPORTABLE
CONTAGIOUS BOVINE PLEUROPNEUMONIA IS REPORTABLE
TRUE ITS REPORTABLE
CONTAGIOUS BOVINE PLEUROPNEUMONIA CLINICAL SIGNS
CAUSES MARBLED LUNGS
HIGH FEVER, DEPRESSION, COUGHING, DROP IN MILK PRODUCTION
CHRONIC- FIBROSIS ENCAPSULATION OF NECROTIC TISSUE
MYCOPLASA MYCOIDES SUBSPECIES MYCOIDES
CONTAGIOUS BOVINE PLEUROPNEUMONIA
MARBLED LUNGS
CONTROL OF CONTAGIOUS BOVINE PLEUROPNEUMONIA
TEST AND SLAUGHTER ALL INFECTED AND IN CONTACT ANIMALS
CONTROL CONTAGIOUS BOVINE PLEUROPNEUMONIA IN ENDEMIC REGIONS
ABX-REDUCE TRANSMISSION PROHIBIT MOVEMENT OF ANIMALS QUARANTINE NEW ANIMALS CULL POSITIVE ANIMALS VACCINATION
MYCOPLASMA BOVIS
CHRONIC DISEASE
SEVERE IN CALVES
RESPIRATORY DISEASE, ARTHRITIS, MASTITIS
MYCOPLASMA BOVIS LESIONS IN THE LUNGS
SCATTERED RICE ABSCESSES
TX FOR MYCOPLASMA BOVIS
SEPARATE POSITIVE ANIMALS
ABX
MASTITIS IN MYCOPLASMA BOVIS
HIGHLY INFECTIOUS
PURULENT PLUGS
LOSS OF MILK PRODUCTION
GLAND FIBROSIS
ENZOOTIC PNEUMONIA IN PIGS
HUGE POPULATION OF PIGS TRANSMISSION BY AEROSOLS
OUTBREAK DUE TO HIGH TEMPERATURES, POOR VENTILATION, OVERPOPULATION
CLINICAL SIGNS OF MYCOPLASMA HYOPNEUMONIAE
COUGHING, POOR GROWTH RATE, RESP DISTRESS
PULMONARY CONSOLIDATION CONFINED TO CRANIAL AND MIDDLE LUNG LOBES
ENZOOTIC PNEUMONIA OF PIGS DIAGNOSIS
PCR
OR FOR HERD - ELISA
TREATMENT FOR M. HYOPNEUMONIAE
VACCINES REDUCE CLINICAL SIGNS NOT TRANSMISSION
ABX IN FEED (SOME RESISTANCE)
DEVELOP PATHOGEN FREE HERDS
SURVEILLANCE- MONITOR AT SLAUGHTER AND SEROLOGICALLY
MYCOPLASMA GALLISEPTUM
CHRONIC RESP DISEASE IN CHICKENS
INFECTION OF EGG OR AEROSOL
COUGHING, NASAL DC, SINUSITIS, REDUCED EGG PRODUCTION
MYCOPLASMA SYNOVIAE
INFECTIOUS SYNOVITIS IN CHICKENS AND TURKEYS TRANSMITTED BY AEROSOLS SYNOVITIS, ARTHRITIS, RESPIRATORY SIGNS TREAT WITH TETRACYCLINE REPORTABLE
MYCOPLASMA SYNOVIAE AND MYCOPLASMA GALLISEPTICUM ARE REPORTABLE
TRUE M. SYNOVIAE AND M GALLISEPTICUM ARE REPORTABLE
DIAGNOSIS OF MYCOPLASMA IN BIRDS
ISOLATION
AGGLUTINATION TEST
PCR
TREATMENT OF MYCOPLASMA IN BIRDS
SPF FLOCKS, USE TYLOSINE TO TREAT EGGS (M. GALLISEPTUM) , VACCINES AVAILABLE
HEMOTROPHIC MYCOPLASMAS
ATTACH TO SURFACE OF RED BLOOD CELLS
WALLESS, PLEIOMORPHIC, ROD SHAPED, GRAM -
MAY BE ZOONOTIC
FELINE INFECTIOUS ANEMIA
M. HAEMOPHILUS** MOST PATHOGENIC
M. HAEMOMINUTUM *** MOST FREQUENT SUBCLINICAL CARRIER STATE
HEMOTROPHIC MYOPLASMAS IN DOGS
M HAEMOCANIS
CANDIDATUS M HAEMOPARVUN
HEMOTROPHIC MYCOPLASMA IN PIGS
M. SUIS
M PARVUM- NON PATHOGENIC
HEMOTROPHIC MYCOPLASMA IN CATTLE
M WENYONII
TRANSMISSION OF HEMOPLASMAS IN CATS AND DOGS
VERTICAL TRANSMISSION FROM QUEEN TO KITTENS INFECTED BLOOD AGGRESSIVE INTERACTIONS- CAT FIGHTS ARTHOPODS IN SALIVA
RISK FACTORS OF CATS
OLDER CATS, OUTDOOR, INTACT, FIV/FELV, NEOPLASIAS, IMMUNOSUPPRESSION
RISK FACTORS OF DOGS
YOUNG DOGS, CROSS BREEDS, KENNEL RAISED, MALE DOGS, STRESS, IMMUNOSUPPRESSION OR AFTER SPLENECTOMY
HEMOPLASMA CAUSES
HEMOLYTIC ANEMIA
RUPTURED RBCS
ERYTHROCYTES BOUND ANTIBODIES- ENLARGED LIVER AND SPLEEN
M. HAEMOPHILUS CAUSES
HEMOLYTIC ANEMIA DURING ACUTE INFECTION
DOES NOT REQUIRE CONCURRENT DISEASE TO CAUSE
CLINICAL SIGNS OF HEMOPLASMAS
PALLOR- WHITE MUCOUS MEMBRANES , LETHARGY, FEVER, WEIGHT LOSS, SPLENOMEGALY, DEPRESSION, DEHYDRATION
C.M. HAEMOINUTUM IS CARRIER STATE IN
CATS
DIAGNOSIS OF HEMOPLASMAS
BLUE DOTS ON SURFACE OF RBCS BLOOD SMEAR, SEROLOGY, PCR** PREFERRED METHOD
TREATMENT OF HEMOPLASMAS
DOXYCYCLINE, BLOOD TRANSFUSION
FLEA CONTROL
MYCOPLASMA SUIS TRANSMISSION
LICE, INFECTED INSTRUMENTS
OUTBREAKS OF M SUIS ARE RELATED TO
STRESS
YOUNG PIGLETS- VERY SEVERE ANEMIA
M SUIS IS USUALLY
SUBCLINICAL
CANDIDATUS M HAEMOLAMAE
MILD TO SEVERE ANEMIA IN LLAMAS
ACUTE IN YOUNG ANIMALS
TREATMENT OXYTETRAYCLINES
CHRONICALLY INFECTED FOR LIFE
