ACTINOBACILLUS Flashcards

1
Q

ACTINOBACILLUS PLEUROPNEUMONIAE

A

VERY IMPORTANT IN SWINE REARING
WORLDWIDE DISTRIBUTION
PIGS <6 MONTHS
HOST SPECIFIC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

TWO TYPES OF A. PLEUROPNEUMONIAE

A

BIOTYPE 1 NAD DEPENDENT
BIOTYPE 2 NAD INDEPENDENT

16 SEROTYPES - GEOGRAPHIC DIFFERENCES, VARYING VIRULENCE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

HOW IS A PLEUROPNEUMONIA TRANSMITTED ?

A

DIRECT PIG TO PIG - AEROSOL
SPREAD THROUGH STABLE PEN TO PEN VIA VENTILATION
REGROUPING OF PIGS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

WHERE IS A. PLEUROPNEUMONIAE COMMENSAL

A

NOSE AND TONSILS

LUNG NODULES OF RECOVERED PIGS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

WHAT ARE THE PREDISPOSING FACTORS FOR A PLEUROPNEUMONIAE

A

VIRULENCE, STRESS, PEN CHANGES, CLIMATE, AIRLFLOW, OVERPOPULATION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

WHERE DOES A PLEUROPNEUMONIAE EFFECT

A

TERMINAL BRONCHI AND ALVEOLI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

VIRULENCE FACTORS OF A PLEUROPNEUMONIAE

A

ADHESION-FIMBRIAE

MULTIPLICATION NEEDS FE- TRANSFERRIN BINDING PROTEINS, HEMOGLOBIN BINDING PROTEINS

EXOTOXINS- APX TOXINS MAKE PORES IN RED BLOOD CELLS, ENDOTHELIUM, NEUTROPHILS, AND MACROPHAGES (O2 RADICALS AND LYTIC)

CAPSULE(EVASION OF HOST IMMUNITY)

LPS (LIPID A ENDOTOXINS)

OUTER MEMBRNE PROTEINS

ENZYMES AND PROTEASES

HEAT SHOCK PROTEINS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

EXOTOXINS OF A. PLEUROPNEUMONIAE

A

I- STRONG HEMOLYTIC AND CYTOLYTIC
II- WEAK HEMOLYTIC AND CYTOLYTIC
III- STRONG CYTOLYTIC
IV- NECESSARY FOR VIRULENCE IN ALL SPECIES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

SYMPTOMS OF A. PLEUROPNEUMONIAE

A

HYPERACUTE- HIGH INFECTION DOSE, DEATH WITHIN HOURS
ACUTE
CHRONIC- STUNTED GROWTH, LUNG DAMAGE, ADHESIVE PLEURITIS, RESPIRATORY DISTRESS, OPEN MOUTH BREATHING, FEVER, ANOREXIA, HEMORRHAGIC NECROTIZING PNEUMONIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

DIAGNOSIS OF A PLEUROPNEUMONIAE

A

SYMPTOMS, AUTOPSY, BACTERIAL CULTURE- REQUIRES NAD STAPHYLOCOCCUS, CO2 ENRICHMENT, SLOW GROWER

SEROLOGY AT FARM LEVEL

DETECTION OF CARRIERS- PCR SAMPLES FROM NOSE AND TONSILS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

TREATMENT AND PREVENTION A. PLEUROPNEUMONIAE

A

HYGIENE, ABX PARENTERAL (INJECTION) IF SICK, IF NOT YET SICK PER OS
LITTLE ACQUIRED RESISTANCE TO ABX

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

VACCINE FOR A. PLEUROPNEUMONIAE SHOULD INCLUDE

A

APX TOXIN, TRANSFERRIN BINDING PROTEIN, TYPE 4 FIMBRIAE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ACTINOBACILLUS SUIS

A

OBLIGATE SYMBIOTIC- VAGINA AND TONSILS

FACULTATIVE PATHOGENIC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ACTINOBACILLUS SUIS VIRULENCE

A

APX TOXINS SIMILAR TO TYPE I AND II IN A. PLEUROPNEUMONIAE CYTOLYTIC AND HEMOLYTIC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

WHAT IS A SIGN THAT ACTINOBACILLUS SUIS IS ON YOUR FARM?

A

DEAD MICE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

WHERE IS A. SUIS FOUND IN HEALTHY ANIMALS

A

VAGINA AND TONSILS

17
Q

A SUIS IN YOUNG PIGS

A

ACUTE MORTALITY, CLINICAL SYMPTOMS SIMILAR TO A PLEUROPNEUMONIAE

18
Q

A SUIS IN OLDER PIGLETS

A

FEVER, ANOREXIA, RESPIRATORY DISTRESS, POLYARTHRITIS

19
Q

A SUIS IN ADULT PIGS

A

SUBCUTANEOUS ABSCESSES, ANOREXIA, FEVER, MENINGITIS POSSIBLE

20
Q

DIAGNOSIS AND TREATMENT

A

CULTURE AND ABX (LITTLE RESISTANCE)

21
Q

ACTINOBACILLUS EQUULI TWO SUBSPECIES

A

SUBSPECIES HAEMOLYTICUS RESERVOIR= HORSE

SUBSPECIES EQUULI RESERVOIR= HORSE AND PIGS

22
Q

ACTINOBACILLUS EQUULI

A

OBLIGATE SYMBIOTIC, FACULTATIVE PATHOGENIC

23
Q

A. EQUULI CAUSES

A

RESPIRATORY DISTRESS

BRONCHITIS, PLEURITIS, PNEUMONIA

24
Q

A. EQUULI IN FOALS

A

SLEEP FOAL DISEASE
ENTERITIS, SEPTICAEMIAE, SLIMY PUS

PREVENT WITH COLOSTRUM
HARD TO TREAT ABX USUALLY FAIL

25
Q

A. EQUULI IN ADULTS

A

ABORTION OR BIRTH OF FOAL WITH SLEEPY FOAL DISEASE
LOCALIZATION IN JOINTS
SEPTICAEMIAE

26
Q

VIRULENCE OF A. EQUULI

A

AQX (RTX) TOXINS- PORE FORMING, HEMOLYTIC

27
Q

A. EQUULI IS FOUND IN CARRIERS WHERE

A

MOUTH AND GI TRACT

28
Q

ACTINOBACILLUS LIGNIERESII

A

WOODEN TONGUE

TIMBER TONGUE

29
Q

WHAT HOST DOES A. LIGNIERSII INFECT

A

CATTLE

FACULTATIVE PATHOGENIC, OBLIGATE SYMBIOTIC

30
Q

WHERE IS THE RESERVOIR FOR A. LIGNIERSII

A

NASOPHARYNX OF SHEEP, CATTLE, HORSES

31
Q

HOW IS A. LIGNIERSII TRANSMITTED

A

ENDOGENOUS BETWEEN COWS- ORAL LESIONS

CONTAMINATED SX MATERIAL, LESIONS AT SURGERY SITE

32
Q

WHAT DOES A LIGNIERSII DO

A

INFECTIOUS TO CONNECTIVE TISSUE, TONGUE

CAPSULE OF CONNECTIVE TISSUE WITH MULTIPLE GRANULOMAS CONTAINING YELLOWISH PUS AND SULFUR GRANULES

33
Q

HOW TO DIAGNOSE A. LIGNIERSII

A

EASY TO CULTURE
HISTOLOGY
MICROSCOPY OF GRANULES

34
Q

TREATMENT OF A LIGNIERSII

A

SX RESECTION OF ABSCESSES
LOCAL DISINFECTION WITH IODINE

ONLY EFFECTIVE IN INITIAL PHASE