Rheumatology Flashcards

1
Q

Anti-CCP AB

A

Rheumatoid Arthritis

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2
Q

Anti-dsDNA AB

A

SLE

May fluctuate with diease activity

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3
Q

Anti-RNP

A

Mixed Connective Tissue Disease

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4
Q

Anti-Centromere

A

Limited Systemic Sclerosis

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5
Q

Anti-Scl 70

A

Diffuse Systemic Sclerosis

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6
Q

Anti-Ro

A

Sjogren’s Syndrome

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7
Q

Anti-La

A

Sjogren’s Syndrome

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8
Q

Anti-Jo1

A

Myositis

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9
Q

Anti-Sm

A

SLE

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10
Q

Anti-cardiolipin AB

A

Anti-Phospholipid Syndrome

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11
Q

cANCA/anti-PR3

A

GPA

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12
Q

pANCA/anti-MPO

A

EGPA

Microscopic polyangitis

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13
Q

C3 and C4

A

Low in immune complex vasculitis especially lupus nephritis

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14
Q

Management of Paget’s Disease

A

Bisphosphonates

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15
Q

Behcet’s Syndrome

A

= oral ulcers, genital ulcers, uveitits

Associated with thrombophlebitis

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16
Q

Drug-Induced Lupus

Drug associated with (TB)

A

Isoniazid

17
Q

Felty’s Syndrome

A

= splenomegaly, RA and neutropaenia

18
Q

Acute VS Chronic in Rheumatology

A

Acute < 6 weeks

19
Q

Co-prescription with allopurinol

Why?

A

NSAIDs/colchicine

Covers any flares as a result from fluctuating uric acid levels

20
Q

Alternative investigation in suspected temporal arteritis

A

Ultrasound

See thickening and narrowing of the temporal artery

21
Q

Management of polymyositis

A

1mg/kg steroids

Usually need an immunosuppressant as well

22
Q

Antibodies seen in drug-induced lupus

A

Anti-histone AB

23
Q

Management of polymyositis

A

1mg/kg of oral steroids

24
Q

Cardiac Associations with Ankylosing Spondylitis (2)

A

Heart Block
= AV dissociation on ECG
Aortic Regurgitation
= see LVH on ECG (deep S1 in V1, tall R in V5)

25
Q

Eye complication seen with HCQ use

A

Retinitis

26
Q

Haematology complication seen with azathioprine (small risk)

A

Lymphoma