Obstetrics and Gynaecology Flashcards
Investigation of Choice
Suspected Ectopic Pregnancy
Transvaginal USS
Sensitising Events Rhesus Disease (3)
Miscarriage >12 weeks
Abdominal Trauma
Invasive Antenatal Testing
Delivery of Anti-D in Rh -VE
Exception
- At 28 weeks
- At birth on confirmation that baby is Rh +VE
Cannot give to sensitised women
Vaccines and Anti-D Injection
Cannot give live vaccines e.g. MMR within 3 months of anti-D injection
Surfactant Production and Delivery
Catecholamines and cortisol released by the foetus at delivery stop the production of surfactant
Umbilical Arteries Carry
Dexoygenated blood
From foetus to the placenta
Umbilical Vein Carries
Oxygenated blood
From placenta to the foetus
Result of Reduced Oxygen Delivery to Foetus (2)
Reduced growth
Reduced movements
Medical TOP
Early VS Late
Early = up to 9+6 Late = from 10+0
Medical TOP Regimen
Oral anti-progesterone
+
Oral or Vaginal Prostaglandin 24-48 hours later
e.g. 200mg mifepristone + misoprostol
Surgical TOP Methods (2)
Vacuum Aspiration = 6-12 weeks
Dilation and Evacuation = 13-24 weeks
Post-Procedure TOP Care
Pregnancy Test should be given at 2-3 weeks
Contraception should be given
Not progesterone contraception - could reverse TOP
Transfer to CTG
Indications (5)
Decelerations after a contraction
Oxytocin augmentation
Pyrexia 37.5 >2 occassions
FHR <110 or >160
Heart Rate Parameters
Normal = 110-160 Non-Reassuring = 161-180 Abnormal = <110 or >180
Decelerations (pathophysiology, relation to contractions)
- Early
- Late
Early = associated with head compression: sync with contraction Late = mediated by chemoreceptors, recovery lasts beyond the contraction
Hyperstimulation =
> 5 contractions in 10 minutes
CTG Signs of Foetal Compromise (3)
Absent accelerations
Decreased baseline variability
Shallow decelerations
Maternal Cardiac Changes (2)
Increased cardiac output - peaks week 24-28
SBP - slight drop in 2nd trimester
Maternal Respiratory Changes (3)
Reduced functional capacity ( < elevation of diaphragm)
Increased tidal volume
Mildly compensated respiratory alkalosis
Maternal Endocrine Changes (4)
Insulin resistant
Reduced bone density
Increased thyroid hormone requirements
Vitamin D deficiency
Maternal Haematological Changes (4)
Iron deficiency anaemia
Hypercoagulable
+ WBC
Gestational thrombocytopaenia
Definition of Gestational HTN
= hypertension + no proteinuria: usually after 20 weeks and resolves within 6 weeks
Investigation of Pre-Eclampsia/HELLP
Bloods = FBC, LFTs, U&Es, coagulation, blood film
Urinary protein: creatinine ratio
Management of Eclamptic Seizures
IV MgSO4
Blood Sugar Parameters in Diabetes
FBG = <5.3
1 hour Post Prandial = <7.8
Definition of Peripartum Cardiomyopathy
= heart failure 2y to LVSD towards the end of pregnancy
EF usually <45%
Often present in pulmonary oedema/symptoms of cardiac failure
Acute Fatty Liver of Pregnancy
- Presentation (4)
- Findings (5)
- Management
Pres: vomiting, abdominal pain, encephalopathy, polydipsia
Findings: Elevated bilirubin Hypoglycaemia Elevated AST/ALT Renal impairment Disordered coagulation
Management: supportive, delivery of baby, N-acetylcysteine
Examples of Prostaglandins used in Labour (3)
Propress
Prostin
Misoprost - medical miscarriage, where intrauterine death has occured
Oxytocin
- Method of Action
- Foetal Distress
Action = stimulates uterine contractility, cervical ripening
= increases contraction frequency and resting tone
FD = bradycardia, transient acidosis
Syntometrine
- Action
- When to Use
= results in sustained tonic uterine contraction
- Only post-natally, if accidentally given antenatal need to deliver immediately
Use of Tocolysis
Used to halt or slow pre-term labour
e.g. atosiban, ritodrine, terbutaline
Pethidine
- Delivery
- Foetal Effects
= IM injection
Can cause decreased FHR variability: directly acts on the foetal myocardial conducting system
Testing for Chlamydia or Gonorrhoea
- Male
- Female
Male = first void urine NAAT Female = self-taken vulvo-vaginal swab
Describing a foetus as engaged
More than 2/5ths of the foetus are in the pelvis
Maternal Screening in Pregnancy
Sickle Cell and Thalassaemia: should be done by 10 weeks
Infection: should be done by 12 weeks, if refuse re-offer at 20 weeks
HIV, Hepatitis B, Syphilis
Needs to be done every pregnancy
If maternal Hepatitis B infection
Give foetus vaccine at 0,4,8,12,16 and 52 weeks
Combined Trisomy 13, 18 and 21 Testing
11-14 weeks
= maternal age + crown-rump length + nuchal translucency + BhCG + PAPP-A
Quadruple Testing
14-20 weeks
= maternal age + AFP + BhCG + unconjugated oestradiol + inhibin A
When is anomaly scan offered?
18-20+6 weeks
Blood Spot Test Post-Natal
Usually between days 5-9
= sickle cell disease, cystic fibrosis, congenital hypothyroidism, IMDs
USS for assessment of hip dysplasia
Abnormal Exam = USS within 2 weeks
Risk Factors = USS within 6 weeks
1st line assessment of Newborn Hearing
Automated otoacoustic emission
Management of pre-eclampsia and eclamptic seizures
- 2nd Choice
Magnesium sulphate
Initial management of seizures = 4g MgSO4 IV over 5 minutes
Can use IV diazepam for prolonged seizures
Acceleration Definitions
= increase in FHR of at least 15 BPM for more than 15 seconds
Deceleration Definitions
= decrease in FHR of at least 15 BPM for more than 10 seconds
2nd Stage Decelerations
= normal
The variability and baseline should be preserved
Limit age for foetal movements
24 weeks
Lithium in Pregnancy
Potentially teratogenic
Try and use other mood stabilisers