Rheumatology Flashcards
First line treatment in Paget’s
Bisphosphonates
Drug which causes gout
Thiazide diuretics
Where do calcium phosphate crystals deposit?
In the cartilage
Associations with:
- De Quervains
- Carpal Tunnel
- Dupytren’s
- RA
- Hypothyroidism
- Cirrhosis
Associations with:
- HLA DR3
- HLA DR5
DR3: T1DM
DR5: Hashimoto’s and pernicious anaemia
Late onset Asthma, Vasculitis, Peripheral Eosinophilia
Churg-Strauss
Similar to Wegener’s but with no granulomas and no rest involvement?
Microscopic Polyangitis
Hameturia, hearing loss and visual disturbance
Alports
What do mutations in these collagen fibres lead to:
a) Type I
b) Type III
c) Type IV
a) Osteogenesis Imperfecta
b) Ehler’s Danlos
c) Alports
Difference between PMR and polymyositis
-In polymyositis CK is raised and muscle weakness
Positively birifringement calcium phosphate crystals
Pseudogout
- Recurrent painful ulceration
- Genital ulcers
- Opthalamic lesions
- Skin lesions
Behcet’s