Rheumatology Flashcards
Treatment dermatomyositis
High dose steroids (#1) until CK normalizes, MTX, avoid sunlight
Hypermobile joints, blindness, intellectual disability, hypotonia
Lowe’s syndrome
Which type of JIA is associated with uveitis, ANA+
Pauciarticular/Oligoarthritis
Requirements to dx kawasaki disease
Fever for at least 5 days, and at least 4/5:
Cervical adenopathy, Extremity swelling, polymorphous rash on trunk, conjunctivitis, swollen tongue/dry fissured lips
How to dx Lyme disease
Lyme antibody titer and confirm with western blot
Tx Lyme disease
Doxycycline if >8
Amoxicillin if <8
How to track severity of lupus?
C3 and C4 will go down with more active/acute disease
Most sensitive test in lupus? Most specific?
ANA (almost all are +); Anti-dsDNA (positive rules it in)
How to follow active renal disease in SLE
Increased anti-DNA titers, decreased levels of C3, C4, and CH50
What antibody is frequently positive in drug induced lupus?
Anti-histone
When does the renal involvement occur in HSP? How to monitor?
Can occur 3 months after disease onset. Check urine weekly x 3 months, then monthly x 3 months
HSP is a vasculitis of which vessels? Kawasaki?
HSP- small vessels, Kawasaki- medium vessels
When should aspirin be dc’d in kawasaki disease?
When all acute phase reactants return to normal
What labs to check in sarcoidosis
Calcium, Vitamin D, ESR, CRP
What conditions place patients at increased risk of SCIFE?
hypogonadal conditions, hypothyroidism, growth hormone therapy, and renal osteodystrophy
Recurrent episodes lasting <1 day, which include 2 or more of the following: fever, abdominal pain, chest pain, arthritis, and a family history of the disorder
Familial Mediterranean fever (recurrent polyserositis)
8 yo girl with a temp 102.4° F with exudative pharyngitis, several aphthae on the buccal mucosa, and tender anterior cervical lymphadenopathy. Similar signs and symptoms both 5 and 11 weeks earlier. Dx? How to tx?
Periodic fever with Aphthous ulcers, pharyngitis and Adenitis. Tx with steroids
Tx pityriasis rosea
Sun exposure
Papular lesion on the foot sole in a child walking barefoot at pool .Caused by what?
Atypical mycobacteria
Non-scaling erythematous annular lesion on skin
Granuloma annulare
Tx tinea capitis
PO griseofulvin 6-12 weeks
What to monitor for in kids with NF1?
Pheochromocytoma and renal artery stenosis
Treatment of onychomycosis
Oral terbinafine or itraconazole
When should infantile acne resolve?
After 3 months of age
