FEN/Nutrition Flashcards
Serum osmolality equation
2Na + (BUN/2.8) + (glucose/18)
What meds are associated with metabolic alkalosis?
Loops (Furosemide) and thiazides (HCTZ and metolazone)
What meds are associated with metabolic acidosis?
Acetazolamide and potassium sparing agents like spironolactone
What is the primary issue in type 1 distal tubular acidosis?
Inability to acidify urine/ excrete H+ in the urine (urine pH >5.5)
What is the primary issue in type 2 proximal tubular acidosis?
Inability to absorb HCO3 (urine pH <5.5)
What is the primary issue in RTA type 4?
Resistance to aldosterone, hyperkalemia
Infant that appears well at birth, but later develops lethargy, poor feeding, seizures. Elevated serum ammonia and elevated anion gap metabolic acidosis on labs.
Organic acidemias (methylmalonic/proprionic/isovaleric acidemia)
Infant that appears well at birth, but later develops lethargy, poor feeding, seizures. Elevated serum ammonia and no metabolic acidosis.
Urea cycle defects
Daily requirement of sodium
2-3 mEq/kg/day
Inheritance of nephrogenic DI
X-linked (only found in males)
What should urinary sodium be in SIADH
> 25
When is hypertonic sodium (3%) indicated
When serum sodium <120
Next step if fluid restriction is not adequate in SIADH
Furosemide or hypertonic saline
What is the total body sodium in dilutional hyponatremia
NORMAL
How do you distinguish dilutional hyponatremia from 3rd spacing?
Urine sodium is high in dilutional hyponatremia
Urine sodium is LOW in 3rd spacing
Total body sodium in nephrotic syndrome
Labs will report hyponatremia, but total body sodium is elevated
Daily requirement of potassium
1-2 mEq/kg/day
What electrolyte disturbance causes muscle weakness and QT prolongation
Hypocalcemia
Infant with abdominal mass who becomes hypotensive, non-palpable pulses and distant heart sounds. EKG with widened QRS complex. Immediate treatment?
Adrenal failure with hyperkalemia and electromagnetic dissociation. Tx with calcium chloride
How do you calculate FeNa
(Urine sodium/serum sodium) divided by (Urine creatinine/plasma creatinine)
What FeNa indicates low urinary sodium loss? High urinary sodium loss?
2.5= high
How many mEq/L/day should sodium be decreased in hypernatremia to avoid cerebral edema?
No more than 10-12 mEq/day
If dehydration is chronic, sodium should be decreased at what rate per hour
0.5 to 1 mEq per hour
Child with tachycardia, decreased tears and urine production. What % dehydration and how to replace?
5% or 50cc/kg. Add 50 cc/kg to maintenance, replace the first 1/2 over 8 hours, remaining over 16 hours.
Child with tachycardia, decreased urine, sunken eyes, poor skin turgor, sunken fontanelle. What % dehydration and how to replace?
10% or 100cc/kg. Add 100cc/kg to maintenance. Give 20cc/kg over first hour, remaining 1/2 over next 7 hours and rest over 16 hours
Child with signs of dehydration, plus signs of shock, such as delayed cap refill time. What percent dehydration and how to replace?
15% or 150cc/kg. Add 150cc/kg to maintenance. Give 20cc/kg boluses until you see clinical improvement. Take remaining and replace over 24 hours
How does glucose affect serum sodium measurement?
Every 100 mg/dl increase in glucose above normal lowers serum sodium by 1.6 mg/dl
What is normal serum osmolality?
around 300