Rheum/MSK Flashcards
Anti CCP
RA
Anti dsDNA
SLE
Anti-Ro, anti-La
Sjogren’s syndrome, SLE
Serum ACE
Sarcoidosis
Anti-centromere antibody
Limited scleroderma
Anti Jo-1
Polymyositis with lung involvement (may be dermatomyositis)
Negatively birefringent crystals under polarised light (needle-like)
Gout
Anti-cardiolipin
SLE + APLS
Heliotropic rash and Gottron’s papules
Dermatomyositis
Headache, raised ESR, trouble getting out of chair
GCA with polymyalgia rheumatica
Anti-Smith
SLE
Global loss of joint motion with stiffness
Adhesive capsulitis
Anti-SCL-70 (anti topoisomerase)
Systemic sclerosis
Polyarthritis, conjunctivitis, urethritis
Reactive arthritis (can’t see, can’t pee, can’t climb a tree)
Positively birefringent crystals under polarised light
Pseudogout
IgA with purpuic rash
Henoch-Schonlein purpura
Anti-GBM
Goodpastures
Shawl’s sign
Dermatomyositis
Tensilon test
Myasthenia gravis
Wrist pain on forced thumb adduction and flexion
De Quervain’s tenosynovitis
Prominent and tender tibial tubercle
Osgood-Schlatter’s disease
Hypopigmentation + autoimmune disease
Vitiligo
Arthalgia + uveitis + orogenital ulcers
Behcet’s disease
Positive Schirmer’s
Sjogren’s syndrome
Question mark posture
Ankylosing spondylitis
Arthralgia + reduced lung volumes
SLE
Obese boy - hip flexed, abducted and externally rotated
Slipped femoral epiphysis
Round-shouldered
Scheuermann’s disease
Gold standard for diagnosing Sjogren’s
Salivary gland biopsy (lymphocytic infiltrate)
Investigations for pathological fracture (2)
- DEXA (OA)
- CMP/Bence-Jones (myeloma)
Pencil in cup
Psoriasis
RA + splenomegaly
Felty’s syndrome
Contortionist
Ehlers-Danlos syndrome
Back pain + TB
Pott’s disease of the spine
Increased trabeular pattern and cortical thinking of the rigth hemipelvis with loss of joint space and osteophyte formation of the right hip
Paget’s disease of bone
PAS positive macrophages in intestinal biopsies
Whipple’s disease
Absent callus
Delayed union
Painful shoulder after seizure
Posterior dislocation
Twisting injury
Meniscal tear
Posterior fat pad sign
Radial head fracture
Cancer associated with Paget’s disease of bone
Osteosarcoma
Gait seen in proximal myopathy
Waddling gait
Back pain + anterior uveitis
Ank spond
DRUG SE: nephrotic syndrome
Gold
DRUG SE: pulmonary and hepatic fibrosis
Methotrexate
DRUG SE: reversible oligospermia
Sulfasalazine
DRUG SE: gum hypertrophy
Ciclosporin
Others: phenytoin, calcium channel blockers
DRUG SE: exfoliative dermatitis
Gold
DRUG SE: irreversible retinopathy and alopecia
Hydroxychloroquine
DRUG: scleroderma crisis
ACE inhibitor