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Buzzword city > Haem > Flashcards

Haem Flashcards

1
Q

Normocytic anaemia 6 weeks after flucloxacillin therapy

A

Autoimmune haemolytic anaemia

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2
Q

Osteopenia/lytic lesions + hypercalcaemia + rouleaux

A

Multiple myeloma

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3
Q

Target cells

A

Thalassaemia

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4
Q

Stomatocytes

A

Thalassaemia

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5
Q

Hypersegmented neutrophils

A

Megaloblastic anaemia

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6
Q

Heinz bodies and bite cells

A

G6PDH deficiency or pyruvate kinase deficiency

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7
Q

Jaundice after eating fava beans/ciprofloxacin/sulphonamide

A

G6PDH deficiency

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8
Q

Spherocytes

A

Hereditary or autoimmune haemolytic anaemia

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9
Q

Schistocytes

A

Microangiopathy (e.g. DIC) or intravascular prostheses

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10
Q

Haemolytic anaemia and aplastic anaemia after parvovirus infection

A

Sickle cell anaemia

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11
Q

Acanthocytes

A

Severe liver disease (hyperlipidaemia)

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12
Q

Cold-reacting antibodies (4)

A
  1. HIV
  2. Mycoplasma
  3. EBV
  4. Lymphoma
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13
Q

Reticulocytes

A

Haemolysis

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14
Q

Anaemia and peripheral neuropathy

A

B12 deficiency

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15
Q

Young boy with swollen knee

A

Haemophilia

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16
Q

Tissue death and bleeding in a septic patient

A

DIC

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17
Q

Jaundice and kidney failure after diarrhoea in child

A

HUS

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18
Q

FTL3 mutation

A

AML

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19
Q

Marrow >20% blasts

A

AML, ALL

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20
Q

TEL-AML1 mutation

A

ALL

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21
Q

Philadelphia chromosome/BCR-ABl/9 to 22

A

CML

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22
Q

Reed-Sternberg cells

A

Hodgkin lymphoma

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23
Q

Facial lymphoma caused by EBV

A

Burkitt’s lymphoma

24
Q

Starry sky appearance

A

Burkitt’s lymphoma

25
Mesenteric lymphadenopathy
Non-Hodgkin lymphoma
26
CD 19, 20, 21, 23, 32, 25, 40
B cell neoplasm
27
CD 2, 3, 5, 7
T cell neoplasm
28
5q mutation
Myelodysplaia
29
Replacement of stem cells with fat in bone marrow
Aplastic anaemia
30
Pancytopenia in Ashkenazi Jew
Fanconi anaemia
31
JAK2 mutation
Myeloproflierative disorder (PV, ET, PMF)
32
Teardrop cells, blasts, gout and pancytopenia
Myelofibrosis
33
Pruritis, red skin and headache
PRV
34
Treat with Glivec (imatinib)
CML
35
SLE, livedo reticularis and recurrent miscarriage
Antiphospholipid syndrome
36
Lupus anticoagulant, anti-cariolipin, anti-B2-glycoprotein-I, anti-ApOH
Antiphospholipid sydrome
37
Pancytopenia, thrombosis, haemolytic anaemia and positive Ham test What's the treatment?
Paroxysmal nocturnal haematuria Ecluzimab
38
Hair-on-end skull, frontal and parietal bossing
Beta thalassaemia
39
Most common complication in multiple myeloma
Fractures
40
Iron-related complications of myelodysplastic diseases
Iron overload and refractory anaemia
41
Thrombosis 4 days after heparin
Heparin-induced thrombocytopenia
42
Afro-Caribbean
Sickle cell
43
Abdo pain + headaches after a respiratory infection
Sickle cell crisis
44
DRUG SE: folate deficiency (6)
1. Sulfasalazine 2. Trimethoprim 3. Anticonvulsants 4. Methotrexate 5. Metformin 6. OCP
45
Burr cells
Uraemia
46
Howell-Jolly bodies
Hyposplenism
47
Lymphoplasmacytoid cells
Waldenstrom's macroglobulinaemia
48
Osmotic fragility test
Hereditary spherocytosis
49
Cancer associated with pernicious anaemia
Gastric
50
Renal failure + light chains
Multiple myeloma
51
RA + splenomegaly + pancytopenia
Felty's syndrome
52
Hepatosplenomegaly + pigmentation + anaemia + pathological fractures
Gaucher's syndrome
53
Non-existent coagulation factor
VI
54
Monoclonal spikes
Multiple myeloma, MGUS
55
Bence-Jones proteins
Multiple myeloma
56
Pepperport skull (lytic lesions)
MM, hyperparathyroidism
57
Schilling test
B12

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