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Buzzword city > Haem > Flashcards

Haem Flashcards

1
Q

Normocytic anaemia 6 weeks after flucloxacillin therapy

A

Autoimmune haemolytic anaemia

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2
Q

Osteopenia/lytic lesions + hypercalcaemia + rouleaux

A

Multiple myeloma

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3
Q

Target cells

A

Thalassaemia

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4
Q

Stomatocytes

A

Thalassaemia

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5
Q

Hypersegmented neutrophils

A

Megaloblastic anaemia

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6
Q

Heinz bodies and bite cells

A

G6PDH deficiency or pyruvate kinase deficiency

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7
Q

Jaundice after eating fava beans/ciprofloxacin/sulphonamide

A

G6PDH deficiency

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8
Q

Spherocytes

A

Hereditary or autoimmune haemolytic anaemia

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9
Q

Schistocytes

A

Microangiopathy (e.g. DIC) or intravascular prostheses

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10
Q

Haemolytic anaemia and aplastic anaemia after parvovirus infection

A

Sickle cell anaemia

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11
Q

Acanthocytes

A

Severe liver disease (hyperlipidaemia)

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12
Q

Cold-reacting antibodies (4)

A
  1. HIV
  2. Mycoplasma
  3. EBV
  4. Lymphoma
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13
Q

Reticulocytes

A

Haemolysis

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14
Q

Anaemia and peripheral neuropathy

A

B12 deficiency

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15
Q

Young boy with swollen knee

A

Haemophilia

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16
Q

Tissue death and bleeding in a septic patient

A

DIC

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17
Q

Jaundice and kidney failure after diarrhoea in child

A

HUS

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18
Q

FTL3 mutation

A

AML

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19
Q

Marrow >20% blasts

A

AML, ALL

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20
Q

TEL-AML1 mutation

A

ALL

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21
Q

Philadelphia chromosome/BCR-ABl/9 to 22

A

CML

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22
Q

Reed-Sternberg cells

A

Hodgkin lymphoma

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23
Q

Facial lymphoma caused by EBV

A

Burkitt’s lymphoma

24
Q

Starry sky appearance

A

Burkitt’s lymphoma

25
Q

Mesenteric lymphadenopathy

A

Non-Hodgkin lymphoma

26
Q

CD 19, 20, 21, 23, 32, 25, 40

A

B cell neoplasm

27
Q

CD 2, 3, 5, 7

A

T cell neoplasm

28
Q

5q mutation

A

Myelodysplaia

29
Q

Replacement of stem cells with fat in bone marrow

A

Aplastic anaemia

30
Q

Pancytopenia in Ashkenazi Jew

A

Fanconi anaemia

31
Q

JAK2 mutation

A

Myeloproflierative disorder (PV, ET, PMF)

32
Q

Teardrop cells, blasts, gout and pancytopenia

A

Myelofibrosis

33
Q

Pruritis, red skin and headache

A

PRV

34
Q

Treat with Glivec (imatinib)

A

CML

35
Q

SLE, livedo reticularis and recurrent miscarriage

A

Antiphospholipid syndrome

36
Q

Lupus anticoagulant, anti-cariolipin, anti-B2-glycoprotein-I, anti-ApOH

A

Antiphospholipid sydrome

37
Q

Pancytopenia, thrombosis, haemolytic anaemia and positive Ham test What’s the treatment?

A

Paroxysmal nocturnal haematuria Ecluzimab

38
Q

Hair-on-end skull, frontal and parietal bossing

A

Beta thalassaemia

39
Q

Most common complication in multiple myeloma

A

Fractures

40
Q

Iron-related complications of myelodysplastic diseases

A

Iron overload and refractory anaemia

41
Q

Thrombosis 4 days after heparin

A

Heparin-induced thrombocytopenia

42
Q

Afro-Caribbean

A

Sickle cell

43
Q

Abdo pain + headaches after a respiratory infection

A

Sickle cell crisis

44
Q

DRUG SE: folate deficiency (6)

A
  1. Sulfasalazine
  2. Trimethoprim
  3. Anticonvulsants
  4. Methotrexate
  5. Metformin
  6. OCP
45
Q

Burr cells

A

Uraemia

46
Q

Howell-Jolly bodies

A

Hyposplenism

47
Q

Lymphoplasmacytoid cells

A

Waldenstrom’s macroglobulinaemia

48
Q

Osmotic fragility test

A

Hereditary spherocytosis

49
Q

Cancer associated with pernicious anaemia

A

Gastric

50
Q

Renal failure + light chains

A

Multiple myeloma

51
Q

RA + splenomegaly + pancytopenia

A

Felty’s syndrome

52
Q

Hepatosplenomegaly + pigmentation + anaemia + pathological fractures

A

Gaucher’s syndrome

53
Q

Non-existent coagulation factor

A

VI

54
Q

Monoclonal spikes

A

Multiple myeloma, MGUS

55
Q

Bence-Jones proteins

A

Multiple myeloma

56
Q

Pepperport skull (lytic lesions)

A

MM, hyperparathyroidism

57
Q

Schilling test

A

B12

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