Endocrinology

Question 1

Adrenal insufficiency and bitemporal hemianopia

Answer 1

Empty sella syndrome

Question 2

Elderly man with osteoporosis despite supplements

Answer 2

Testosterone deficiency

Question 3

Psamomma bodies

Answer 3

Papillary thyroid cancer

Question 4

Diabetes drug contraindicated in heart failure

Answer 4

Pioglitazone

Question 5

Orphan Annie eyes

Answer 5

Papillary thyroid cancer

Question 6

Headache and tachycardia

Answer 6

Phaeochromocytoma

Question 7

Pigmentation and postural hypotension

Answer 7

Addison’s disease

Question 8

Pituitary dysfunction after pregnancy

Answer 8

Sheehan’s syndrome (hypopituitarism due to haemorrhage post-partum)

Question 9

Galactorrhoea, dry vagina, hirsutism, amenorrhoea

Answer 9

Prolactinoma

Question 10

Can’t wear hat

Answer 10

Paget’s disease

Question 11

Resized ring

Answer 11

Acromegaly

Question 12

Chvostek’s/Trousseau’s signs

Answer 12

Hypocalcaemia

Question 13

Pathological fracture, constipation, kidney stones and depression

Answer 13

Hypercalcaemia

Question 14

Anosmia with hypopituitarism (symptoms of lost sex hormones mainly)

Answer 14

Kallman’s syndrome

Question 15

Pancreatic cancer, parathyroid adenoma, prolactinoma

Answer 15

MEN1 syndrome

Question 16

Halo on ultrasound

Answer 16

Follicular adenoma

Question 17

Anti-TPO

Answer 17

Hashimotos (less commonly in Graves)

Question 18

Anti-thyroglobulin

Answer 18

Graves (less commonly in Hashimoto’s)

Question 19

Anti-insulin, anti-GAD, anti-islet

Answer 19

T1DM

Question 20

Polyuria, polydipsia and weight loss

Answer 20

Diabetes

Question 21

Buffalo hump, moonlike facies

Answer 21

Cushing’s syndrome

Question 22

Exophthalmos

Answer 22

Graves’ disease

Question 23

Croaky voice

Answer 23

Hypothyroidism

Question 24

Collapse + hypotension + depigmented patches

Answer 24

Addisonian crisis

Question 25

RET mutation

Answer 25

Medullary thyroid cancer

Question 26

Hyperpigmentation after bilateral adrenalectomy

Answer 26

Nelson’s syndrome

Question 27

Medullary thyroid cancer + phaeochromocytoma + parathyroid hyperplasia

Answer 27

MEN II

Question 28

Cotton wool spots without neovascularisation

Answer 28

Pre-proliferative diabetic retinopathy

Question 29

Peri-orbital tingling post-thyroidectomy

Answer 29

Hypocalcaemia

Question 30

Obese female with malar flush, yellow-tinged skin, altered mental sate, bradycardia, hypothermia and heart failure

Answer 30

Myxoedema

Question 31

Congo red stain for thyroid cancer

Answer 31

Medullary thyroid cancer

Question 32

Treatment of HHS

Answer 32

Saline + insulin + anticoagulation

Question 33

Treatment of DKA

Answer 33

Saline + insulin + potassium

Question 34

Emergency treatment of DKA without IV access/patient has already injected insulin

Answer 34

Glucagon

Question 35

DRUG: electrolyte disturbance seen with amphotericin

Answer 35

Hypokalaemia

Question 36

DRUG: oesophagitis and osteonecrosis of the jaw

Answer 36

Bisphosphonate

Question 37

DRUG: cardiac drug cuasing increased insulin requirement

Answer 37

Thiazides (hyperglycaemia)

Question 38

DRUG SE: SLE drug causing haemorrhagic cystitis

Answer 38

Cyclophosphamide

Question 39

DRUG SE: sore throat and fatigue after carbimazole

Answer 39

Agranulocytosis

Question 40

DRUG: osteoporosis 32-aa peptide

Answer 40

Calcitonin