Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

BOARDS > Rheum > Flashcards

Rheum Flashcards

1
Q

ankylosing spondylitis mainly affects

A

SI joints

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

ankylosing spondylitis more common in

A

males

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

ankylosing spondylitis associated with

A

IBD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

bamboo spine on xray

A

ankylosing spondylitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

night pain and morning back stiffness relieved by exercise

A

ankylosing spondylitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

shiny or scaly skin over the interphalangeal joint

A

gottron’s sign (dermatomyositis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

heliotrope rash, shiny/scaly extensor surfaces and interphalanges, difficulty getting dresses, voice change/difficulty swallowing

A

dermatomyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

most common systemic vasculitis in children

A

HSP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

palpable purpura, heme positive stool, colicky abdominal pain, hematuria

A

HSP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

most common rheumatologic disease of childhood

A

JIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

JIA must present before what age

A

16 (at least 6 weeks in 1 joint)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

morning stiffness with gradual loss of motion and rash

A

JIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ANA in JIA

A

usually positive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

JIA is more common in

A

girls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

polyarthritis JIA

A

5 or more joints in the first 6 months, most females

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

oligoarthritis/pauciarthritis JIA

A

4 or fewer joints during the first 6 months, ANA positive, usually young females, associated with chronic uveitis, boys w/ HLA b27 have a better prognosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

systemic onset JIA

A

aka stills disease, affects males and females equally, extraarticular involvement is common

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

enthesitis related arthritis

A

SI joint pain, more common in boys, HLA-B27

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

first line JIA treatment

A

NSAID (indomethacin, ibuprofen, naproxen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

2nd line JIA treatment

A

steroids and immunosuppressants if NSAIDs don’t work

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

MTX MOA

A

folate antagonist - side effects = GI distress and pulmonary toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

gold standard therapy for JIA

A

methotrexate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

mucocutaneous lymph node syndrome aka

A

kawasaki’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Kawasaki is more common in

A

asian, males, around 2 years old, mostly winter and spring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Kawasaki’s criteria

A

high fever for at least 5 days plus at least 4

  • cervical LAD
  • cracked lips
  • non-exudative conjunctivitis
  • polymorphous exanthem on trunk
  • erythema/ desquamation of hands/feet
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

things common in Kawasaki that are not part of the criteria

A

sterile pyuria, migratory poly arthritis, gallbladder hydrops, thrombocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

thrombocytosis by what day with kawasaki

A

day 5

28
Q

leukocytosis by what day with kawasaki

A

day 12

29
Q

Kawasaki treatment

A

IVIG 2g/kg, initial high dose aspirin of 80mg/kg/day x24-48 hours then maintenance aspirin of 5 mg/kg/day x2 months

30
Q

what vaccines can’t be given after IVIG

A

varicella and MMR cannot be given for 11 months after IVIG

31
Q

Lyme disease is carried by

A

ixodes deer tick

32
Q

ticks need to feed how long to transmit lyme disease

A

36 hours

33
Q

erythema chronic migrans

A

lyme disease

34
Q

second stage of lyme disease

A

carditis, arthritis, neurologic (Bell’s palsy)

35
Q

treatment for Lyme disease if less than 8

A

amoxicillin

36
Q

treatment for Lyme disease if less than 8 and penicillin allergic

A

cefuroxime

37
Q

chills, fever and hypotension after treatment for lyme disease

A

jarisch-herxheimer reaction due to lysis of organism and release of endotoxin

38
Q

urethritis, iritis and arthritis

A

reactive arthritis

39
Q

most common cause of reactive arthritis in the US

A

chlamydia trachomatis

40
Q

reactive arthritis in kids is usually after

A

enteric infection

41
Q

weight loss and fatigue with hilar adenopathy

A

sarcoidosis

42
Q

granulomas in sarcoidosis

A

noncaseating but can secrete vitamin D causing hypercalcemia and hypercalciuria

43
Q

arthritis, rash and uveitis

A

sarcoidosis

44
Q

scleroderma is more common in

A

females

45
Q

sclerodactyly, pulmonary fibrosis and reflux

A

systemic scleroderma

46
Q

linear hyperpigmented patch and shiny hypo pigmented skin with a brown border

A

localized linear scleroderma

47
Q

SLE diagnosis requires

A

4 or more

  • malar rash
  • discoid lesions
  • photosensitivity
  • oral ulcerations
  • arthritis
  • hematologic abnormalities
  • renal abnormalities
  • anti-ds-DNA, and-DNA and anti-Smith Ab’s
  • psychosis
  • positive ANA
48
Q

antibody specific to SLE

A

anti-ds-DNA and anti-smith DNA

49
Q

how to track severity of disease in SLE

A

anti-ds-DNA levels (fluctuate accordingly) or C3 and C4 levels (inversely proportional)

50
Q

rash on trunk and bradycardia with 3rd degree heart block in newborn

A

neonatal lupus

51
Q

most common cause of death in an infant born to a mom with SLE

A

heart block

52
Q

antibody associated with neonatal lupus

A

anti-SSA antibody (anti-Ro) and anti-SSB (anti-la)

53
Q

mild lupus treatment

A

NSAIDs and hydroxychloroquine

54
Q

hydoxychloroquine side effects

A

blurring of vision to permanent retinal damage and ototoxicity

55
Q

treatment for lupus with severe organ involvement

A

cyclophosphamide

56
Q

complications associated with high dose steroids

A

cataracts, glaucoma, osteoporosis, HTN, glucose intolerance, cushingoid features

57
Q

ANA pattern in mixed connective tissue disease

A

speckled ANA

58
Q

antibody in mixed connective tissue disease

A

anti-U1 ribonucleoprotein antibody (anti-U1 RNP)

59
Q

diagnosis in child with systemic JIA now with elevated LFTs, positive d-dimer, prolonged PTT and cytopenia

A

macrophages activation syndrome

60
Q

diagnosis with arthritis, dactylics and pitting of nails

A

juvenile psoriatic arthritis

61
Q

fever, weight loss, migratory arthralgia, nodules in lungs, elevated creatinine, positive c-ANCE

A

granulomatosis with polyangitis (Wegener’s)

62
Q

pathergy test

A

prick skin with needle, pustule or papule surrounded by redness forms within 48 hours with Behcet disease

63
Q

painful recurrent oral and genital ulcers and uveitis

A

Behcet disease

64
Q

antibody that is likely the cause of miscarriages in lupus

A

antiphospholipid antibodies

65
Q

recurrent parotitis, dry eyes and mouth, anti-Ro positive

A

sjogren syndrome

66
Q

PFAPA

A

periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis

67
Q

Turkish girl with fevers for 3 days every 3 months with elevated ESR, CRP and WBC during fevers nut normal in between

A

familial mediterranean fever

BOARDS (24 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions