Fluids & Electrolytes Flashcards
serum osmolality equation
2 x Na + BUN/2.8 + glucose/18
normal serum osmolality
265-285
formula to correct metabolic acidosis
weight x 0.3 x base deficit
acidemia pH
<7.36
alkalemia pH
> 7.44
bicarb in metabolic alkalosis
> 25
bicarb in metabolic acidosis
<25
CO2 in respiratory alkalosis
<40
CO2 in respiratory acidosis
> 40
primary cause of respiratory acidosis
hypoventilation (elevated CO2) ex: CNS disease
primary cause of respiratory alkalosis
hyperventilation (low CO2) ex: pneumonia
leading cause of metabolic acidosis
diarrhea
common causes of metabolic alkalosis
vomiting, prolonged NG suction, pyloric stenosis and CF
lab findings of pyloric stenosis
hypochloremic hypokalemia metabolic alkalosis
pH in pyloric stenosis
high
serum chloride in pyloric stenosis
low
serum potassium in pyloric stenosis
low
serum sodium in pyloric stenosis
low
bilirubin in pyloric stenosis
high
anion gap calculation
sodium - (chloride + bicarb)
normal anion gap
8 to 12 (chloride is elevated)
causes of acidosis with normal anion gap
diarrhea, RTA
type 1 RTA aka
distal RTA
job of proximal tubule
retains bicarb
job of distal tubule
secrete H+
type 1 RTA issue
not secreting H+ into urine resulting in hyperchloremic, hypokalemic metabolic acidosis
type 1 RTA urine pH
> 5.5
type 2 RTA issue
losing excess bicarb in urine (not taking it back up)
type 2 RTA urine pH
<5.5 (distal is still functioning and secreting H+)
type 2 RTA mimicker
acetazolamide (carbonic anhydrase inhibitor)
type 4 RTA issue
resistance to aldosterone or aldosterone deficiency causing hyperkalemia
chloride in elevated anion gap
normal
elevated anion gap associations
Methanol Uremia DKA Paraldehyde Ingestion/Iron/Isoniazid Lactic acid Ethanol/Ethylene glycol Salicylates
daily sodium requirement
3 meq/kg/day (preemies need 6-9)
hypernatremia definition
> 145
improper mixing of formula (not enough water) can cause
hypernatremia
diarrhea effect on sodium
can cause hypernatremia (lose more water than Na)
fetus % body weight water
90%
adolescent/adult % body weight water
60%
high serum osmolality with inappropriately dilute urine
DI
nephrogenic DI pattern
x-linked, males only