Review: Parturition Flashcards

1
Q

What are the 3 Ps of fetal presentation?

A

Presentation, Position, Posture

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2
Q

Describe “presentation” of the fetus:

A

Longitudinal axis of the fetus in relation to the birth canal
Anterior vs. Posterior

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3
Q

Describe “position” of the fetus:

A

Relationship of the DORSUM of the fetus to the quadrants of the maternal pelvis
Dorso-sacral vs. Dorsopubic

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4
Q

Describe “posture” of the fetus:

A

Position of the extremities, head, and neck of the fetus
Examples: head back, wry neck, leg back,

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5
Q

What is the “normal” presentation of a fetus?

A

Anterior presentation
Dorsal-sacral position
Front limbs and head extended

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6
Q

Stage 1 of parturition:

A

Overall restlessness
+/- Anorexia
Separation from herd/flock
Ends with rupture of chorioallantoic membrane

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7
Q

Stage 2 of Parturition:

A

Active contractions with pushing
Ends with passage of the fetus
Should be rapid!

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8
Q

Stage 3 of Parturition:

A

Expulsion of fetal tissue (placenta)
In litter bearing species, cycle between stage 2 and 3 until all fetuses delivered

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9
Q

Stage 1 of Bovine parturition is typically longer in:

A

Heifers

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10
Q

How long does Stage 1 typically last in Bovine species?

A

Average 6 hours, up to 24 hours

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11
Q

Stage 2 in Bovine species typically lasts:

A

2-4 hours on average
Calf can survive up to 8 hours if umbilicus is intact

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12
Q

How long on average should we see the placenta pass in bovine species?

A

8 hours on average

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13
Q

Describe Stage 1 specifically for Equine species:

A

Most mares foal at night, 12a-6a
1-4 hours on average
Can delay if interrupted (need quiet/cameras in foaling barn)

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14
Q

Describe Stage 2 in Equine species:

A

Frequent urination/defecation
Pushing & delivery
11-20 min on average (forceful/fast)

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15
Q

Describe Stage 3 in Equine:

A

Pass placenta in whole by 3 hours (need to layout and check)
“1, 2, 3 Rule”
-Foal standing within 1 hour
-Foal standing and nursing within 2 hours
-Placenta passes entirely in 3 hours

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16
Q

Typical time for Stage 1 of Small Ruminants?

A

Primiparous: 2-12 hours
Pluriparous: 1-2 hours

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17
Q

Typical time for Stage 2 for Small Ruminants?

A

1-3 hours on average, depends on number of fetuses

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18
Q

Timeline for Stage 3 for Small Ruminants?

A

Pass placenta in whole by 1 hour, considered retained at 12 hours

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19
Q

Average time for Stage 1 for Small Animals?

A

16-18 hours on average

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20
Q

Average time for Stage 2 for Small Animals?

A

4-12 hours on average

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21
Q

Average time for Stage 3 for Small Animals?

A

No set time, cycling between stage 2 and 3 until all fetuses are passed
Retained placentas are RARE

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22
Q

In pigs, when do the females start nesting?

A

At least 24 hours before Stage 1

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23
Q

Stage 1 in pigs typically lasts:

A

2-12 hours

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24
Q

Piglets expelled every _____ and duration can be _____ for the whole litter

A

15 min; 2-4 hours

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25
For pigs, fetal membranes are expelled _______ and retained placentas are ____
Between each piglet; rare
26
Camelids Stage 1 lasts:
Average 4 hours Often very stoic, no outward signs
27
Stage 2 for camelids typically lasts:
30-45 min average If longer, examination warranted
28
Stage 3 for camelids typically lasts:
Pass placenta in whole by 6 hours
29
What triggers the onset of parturition?
Fetal stress
30
How does fetal stress initiate parturition?
Maturation of the fetal HPA axis Small space leads to fetal stress, increasing cortisol levels, leading to a chain of events
31
How do progesterone levels affect the onset of parturition?
Decreased progesterone removed the “block” on uterine contractions
32
How do estrogen levels affect the onset of parturition?
Increased estrogen causes induction of oxytocin receptors, pelvic ligament relaxation, vulvar swelling, and uterus becomes responsive to induction of contractions
33
Which hormones cause the pelvic ligaments to relax & what other clinical signs would be noticeable?
Relaxin, Estrogen Gluteal muscles sink, tailhead becomes more prominent, sacrosciatic ligament softens
34
Cortisol levels in the fetus also enhances:
surfactant production (leads to lung maturation) Yay Lungs!
35
Expansion of the birth canal is caused by:
Relaxin, estrogens
36
Maternal behavior prior to parturition is controlled by:
Oxytocin
37
Which two hormones control milk production in the dam?
Prolactin (synthesis) and oxytocin (letdown/ejection)
38
Initiation of uterine contractions is caused by:
PGF, oxytocin
39
Which hormone is responsible for the termination of pregnancy?
PGF
40
Signs of impending parturition:
Mammary enlargement and colostrum production, Enlargement/elongation and laxity of vulva Pelvic (sacrosciatic) ligament relaxation and softening of the perineum area, isolation, decrease in appetite (off feed)
41
Gestation lengths of large animals:
Camelids/mares: 11-12 months Cattle: 283 days (~9.5 months) Sheep: 152 days (~5 months) Goats: 150 days (~5 months) Pigs: 114 days (3 mo, 3 weeks, 3 days)
42
First stage of parturition is initiated by:
The fetus
43
What happens during the first stage of parturition?
Relaxation/Dilation of the cervix, uterine contractions commence, fetus adopts birth posture, chorioallantois enters vagina
44
What are some clinical signs seen during the first stage of parturition?
Isolation/off feed, colic signs, tail flagging/raising, vaginal discharge, milk & colostrum production (Wax plugs in mares)
45
What is the ‘Ferguson Reflex’?
Positioning of the fetus so that it triggers a neuroendocrine response in the cervix, resulting in oxytocin synthesis
46
What happens during the second stage of parturition?
Cervix is completely dilated Uterine contractions continue (Ferguson Reflex) Abdominal contractions begin Fetus enters birth canal –> causing rupture of chorioallantois Fetus is expelled
47
What clinical signs are seen during the second stage of parturition?
Water breaks (chorioallantois rupture, lubrication) Active abdominal contractions Delivery of fetus
48
What happens during the third stage of parturition?
Placental circulation is lost Placental dehiscence and separation occurs Uterine and abdominal contractions continue Placental expulsion
49
What clinical signs are observed during the third stage of parturition?
Expulsion of the placenta!
50
If you see a placenta hanging from an animal should you pull it to help them pass it?
NO
51
How long should stage two (fetal expulsion) last in each species?
Camelid: 5-90 min Bitch: ~6h Queen: 30-60 min/kitten (2-4h) Cow: 30-60 min Ewe: 30-120 min Mare: 12-30 min Sow: 150-180 min (20-30 min b/w piglets)
52
Best methods for predicting parturition in bitches?
Twice daily rectal temps, look for transient drop (98-97.5) Ultrasound for fetal gut motility & renal pelvis P4 levels can help, but not practical
53
Best methods for predicting parturition in mares?
Milk calcium > 200ppm; foaling in 24-72 hours Fast decrease in milk pH from slightly alkaline (7.5) to slightly acidic (6.5-6.8); foaling within 24 hours
54
Best methods for predicting parturition in ruminants?
Breeding dates/physical changes Size of fetus (U/S v. palpation) Calving sensors Drop in rectal temp by 0.5 degrees F at 24 hours before parturition
55
Other possible (but impractical) tests for predicting parturition in ruminants:
blood glucose, blood progesterone, measurement of sacrosciatic ligament relaxation
56
Best methods for predicting parturition in sows?
Breeding dates/physical changes Enlarged mammary glands 1-2 days before farrowing Restlessness and nesting behavior 12-24 hours prior Frequent defecation & urination, inc. resp rate Lie in lateral recumbency last 15-60 min
57
What is dystocia?
Anything that impedes the process of parturition (can be maternal or fetal causes)
58
General maternal causes of dystocia include:
Failure of expulsive forces Obstruction of the birth canal Lack of cervical dilation Uterine torsion
59
What are the uterine causes leading to lack of expulsive forces?
Primary & secondary uterine inertia Uterine damage/rupture
60
What is primary uterine inertia?
Myometrial defects (overstretching, degeneration, infection, heredity)- Hydrops Biochemical deficiencies (milk fever/hypocalcemia; pregnancy toxemia/ketosis) Environmental disturbance (heat/cold stress)
61
What is secondary uterine inertia?
Consequence of another cause of dystocia (exhaustion); i.e. running out of calcium stores
62
What is the most common cause of uterine related dystocias?
Secondary uterine inertia
63
What are abdominal causes leading to lack of expulsive forces?
Inability to strain: age, prepubic tendon rupture, abdominal herniation
64
What things can lead to a “bony” obstruction of the birth canal?
Bony pelvis: fracture, breed, diet, immaturity, neoplasia, disease
65
What is the minimum area the pelvic inlet should be for parturition?
150 cm squared
66
What are some soft tissue abnormalities of the vulva leading to obstruction of the birth canal?
congenital defects, fibrosis, immaturity (heifers) May require episiotomy or C-section
67
What are some soft tissue abnormalities of the vagina leading to obstruction of the birth canal?
congenital defect, fibrosis, prolapse, neoplasia, perivaginal abscess, hymen
68
What are some soft tissue abnormalities of the cervix leading to obstruction of the birth canal?
Congenital defect, fibrosis, failure to dilate
69
What are some soft tissue abnormalities of the uterus leading to obstruction of the birth canal?
Torsion, deviation, herniation, adhesion, stenosis
70
What causes lack of cervical dilation? How do we manage these causes?
Ringwomb (sheep) –> CULL Lack of stimulation (malpositioning of the fetus; prolapse–> manual stimulation) Adhesions/fibrosis (previous traumas, cull female)
71
What is Ringwomb?
Heritable condition in sheep Idiopathic failure of the cervix to dilate C-section required; cull ewe & do not breed offspring
72
How do you address a uterine torsion with a closed cervix?
C-section (usually can untwist after delivery) Rolling or planking cow
73
How do you address uterine torsion with an open cervix?
Detorsion rod If detorsion rod fails: C-section
74
What are fetal causes of dystocia?
Hormone deficiency (failure to initiate birth w/ ACTH/Cortisol; immaturity) Feto-maternal disproportion Fetal maldisposition Fetal death
75
What are examples of causes of fetomaternal maldisproportion?
Sire genetics IVF/Cloned calves: large offspring syndrome Fetal monsters/anomalies: conjoined twins, schistosomus, ankyloses, hydrocephaly
76
Why does fetal death result in dystocia?
Dead fetus cannot initiate parturition- indicator for inducing!
77
What clinical signs might be seen if a fetus is dead?
Mummy/macerated fetus Black vulvar discharge in bitch Premature placental separation in mares (Red bag delivery)
78
Reasons for induction of parturition?
Mismating (should be done early) Prolonged gestation (be 110% SURE!) Edema of mammary gland (dairy) Medical necessity (pregnancy toxemia, hydrops) If likelihood of intervention is high (large fetus, young heifer) Convenience: planned assistance/attendance
79
Golden rule for induction of parturition:
Don’t induce! Let nature run its course
80
Induction of parturition in cattle:
20-40mg Dexmethasone if beyond 270 days (Calve 24-72 hours; avg 48) Tighten interval with prostaglandin (Lutalyse, 25mg - 24-48h, abg 36) Survival good if within 1-2 weeks of due date
81
Common sequelae of induction of parturition in cattle:
Retained placenta Oxytocin to expel
82
Induction of parturition in sheep:
15-20mg Dexamethasone if beyond 137 days (lamb within 36-48 hours) +/- Prostaglandin Dinoprost (Lutalyse), 5-10mg; Cloprostenol (Estrumate), 75-100 micrograms/45kg Survival good if within 1 week of due date
83
Induction of parturition in goats?
CL DEPENDENT! Dinoprost/Lutalyse 5-10mg Cloprostenol/Estrumate 75 micrograms/45 kg At least 144 days gestation, kid within 30-36 hours Survival good if within 1 week of due date
84
If there are concerns for prematurity in goats, before inducing parturition, what should you do?
Give 10-20mg Dexmethasone 6-12 hours before you induce
85
Induction of parturition in pigs?
CL DEPENDENT! 10-20mg PGF2a (Lutalyse) at least 112-113 days in gestation (farrow in 18-36 hours) Can give 5-30 IU oxytocin 20 hours AFTER Lutalyse to inc. % to farrow in subsequent 6 hours
86
What is the stipulation with giving oxytocin IU to sows/gilts for induction?
Higher dose more effective for synchronizing farrowing; BUT lower doses recommended due to risk of fatigue
87
Induction of parturition in mares?
Oxytocin IV or IM 10 IU IV q15-30min by slow drip IV May need 4-6 doses Min 2 cm dilation of cervix May then inc. to 20 IU; can go up to 40-60 IU but watch for colic signs
88
When would be the right time to induce parturition in mares?
ONLY if the mare’s life is in danger
89
Induction of parturition in bitches/queens?
Difficult, fetal death can result prior to parturition P4 receptor blocker (Aglepristone) shown effective Not available in US; no agent to induce queens
90
How would you determine if an animal is truly overdue?
Know gestation lengths! Expectancy dates Owner must be 100% sure of breeding date (be wary, use U/S)
91
Define dystocia:
Difficult birth/delivery
92
What is the typical presentation of of puppies/kittens for delivery?
~30% will face posterior and this is NORMAL Rarely have true “breech” babies
93
What types of breeds typically are not able to whelp unassisted?
Brachycephalics (Frenchies, English bulldogs, pugs, etc)
94
What are the two definite ways to determine if a bitch is ready to whelp?
P4 timing Ultrasound Do NOT go to C-section based on breeding date
95
5 ways to determine if a bitch is having a dystocia?
1. 4 hours of weak contractions and no puppy 2. More than 2 hours between puppies (ideal is every 30 min) 3. More than 30 min of active contractions and straining without a puppy 4. Black or excessive green vulvar discharge and no puppy 5. Large amount of frank blood coming from vulva
96
Q What should you do as soon as a dystocia bitch presents to you?
Give full cost of treatment (exam, surgery, NSAIDs, etc) Complete PE on Dam Vaginal exam Ultrasound (fetal viability, HR)
97
Drugs to use for medical management of dystocia in bitches?
Oxytocin Calcium Gluconate - check ionized calcium before giving Glucose- Karo syrup in warm water with syringe, fluids with dextrose
98
Adjunctive medical therapies for dystocia in bitches?
A Lube/warm water 1:1 ratio 8-10 french red rubber catheter Sedation +/- epidural
99
When would you go to surgery for dystocia?
Failed medical tx, stressed puppies, obstruction
100
What NSAIDs are safe to use in puppies?
Meloxicam, Carprofen No renal issues when used in 3-5 day old pups
101
What anesthetic drugs are safe to induce the bitch for a c-section?
Propofol, Alfaxalone
102
Sedative for bitch before C-section surgery that is safe for puppies?
Opioids (Reversible) Typically use Fentanyl + Naloxone
103
How do we recover neonates after delivery by C-section?
WARM RUB SUCTION OXYGEN Drugs as needed (no Dopram!)
104
When puppies are delivered via C-section, what is one of the first things you should check for?
Cleft palates/congenital malformations Put those puppies aside (they won’t make it) and tend to the ones that will survive
105
Post-op care for dam & babies following C-Section surgery?
Clean disinfectant off teats Adaptil collar/spray Extubate, then introduce puppies Make sure they can walk and urinate prior to discharge Short course of NSAIDs