Restrictive Lung Overview Flashcards
What does DPLD stand for?
Diffuse Parenchymal lung Disease. Slide 4
Outwith the lung what can cause thoracic restriction?
Skeletal issues e.g. scoliosis
Muscle weakness e.g. myo/neuro/myelopathy
Abdominal obesity e.g. compression of contents
Slide 5
What are the 5 classifications of DPLD?
Acute Episodic Chronic due to environmental agents Chronic with systemic disease Chronic with no evidence systemic disease. Slide 6
In restrictive thoracic disease what does the disease of alveolar structures cause?
Impaired alveolar gas exchange so there is a decreased partial pressure of O2 and normal CO2. Slide 8
What are the 6 causes of DPLD?
Fluid in the alveolar air spaces Consolidation of alveolar air spaces Alveolitis Dust-disease Carcinomatosis Eosinophilic. Slide 14
What is the clinical syndrome of DPLD?
Breathless on exertion Cough but no wheeze Finger clubbing Central cyanosis Lung crackles on inspiration Pulmonary fibrosis. Slide 15
What are the diagnostics of DPLD?
Reduced lung volumes Reduced gas diffusion Arterial O2 desaturation Antibodies Checking the sputum for TB Slide 17
What is the treatment of DPLD?
Remove any trigger factor Treat any reversible alveolitis First line is systemic steroids Second line is anti-fibrotic agents. Slide 18
As a cause for DPLD, why does fluid collect in the alveolar air spaces?
It is due to Cardiac Po oedema by heart failure. Slide 9
What is the consolidation of alveolar air spaces?
A mass in the lungs such as pneumonia and infarction. Slide 10
What is alveolitis?
The inflammation of the alveolar walls.
Can be by extrinsic-allergic-alveolitis, drugs or sarcoidosis. Slide 11
How does dust disease cause DPLD?
Through fibrogenic particles such as Asbestosis and non fibrogenic such as Siderosis (Fe), stanosis (Sn) and baritosis (Ba). Slide 13
What is entailed with eosinophilic causes of DPLD?
Type I/III allergic response Drugs Fungal Parasites Autoimmune Slide 14
