Respiratory System Flashcards
What is the main function of the respiratory system?
-exchanging gases; CO2 for O2
Name the two zones of the respiratory system:
-conducting zone
-respiratory zone
Which zone does gas exchange occur in?
-respiratory zone
What are the paranasal sinuses?
-several bones that help form the walls of the nasal cavity that have air-containing spaces
-frontal sinus
-maxillary sinus
-sphenoidal sinus
-ethmoidal sinus
What are the functions of the sinuses?
-producing mucus
-lightening the weight of the skull
The conchae, meatuses, and paranasal sinuses are lined by what type of tissue?
-respiratory epithelium: pseudostratified ciliated columnar epithelium
What are goblet cells?
-specialized columnar epithelial cells that produce mucus to trap debris
What is the purpose of the cilia of the respiratory epithelium?
-removing the mucus and debris from the nasal cavity with a constant beating motion
-sweeping materials towards the throat to be swallowed
What is the pharynx?
-a tube formed by skeletal muscle and lined by mucous membrane that is continuous with the nasal cavities
What are the three major regions of the pharynx?
-nasopharynx
-oropharynx
-laryngopharynx
Where are samples taken from to test for strep throat?
-oropharynx
Which type of epithelial tissue lines the oropharynx and the laryngopharynx?
-stratified squamous epithelium, non-keratinized
As the nasopharynx becomes the oropharynx, the epithelium changes from what to what?
-from pseudostratified ciliated columnar to stratified squamous (non-keratinized)
Name the two distinct sets of tonsils in the oropharynx:
-palatine
-lingual
Where is the laryngopharynx located?
-inferior to the oropharynx and posterior to the larynx
What does the laryngopharynx do?
-continues to the route for ingested material and air until its inferior end, where the digestive and respiratory systems diverge
What is the larynx continuous with?
-the laryngopharynx
From what tissue does the larynx transition into what other tissue?
-it transitions from stratified squamous epithelium into pseudostratified ciliated columnar epithelium + goblet cells
What do the cilia in the larynx do?
-beat the mucus upward towards the laryngopharynx, where it can be swallowed down the esophagus
Describe the anatomy of the trachea:
-extends from the larynx down toward the lungs
-formed by 16-20 stacked C-shaped pieces of hyaline cartilage that are connected by dense connective tissue
-inside lined by pseudostratified ciliated columnar epithelium
What is the bronchial tree?
-the trachea branches into the right and left primary (main stem) bronchi
-these bronchi are also lined with pseudostratified ciliated columnar epithelium + goblet cells
What does the respiratory zone include?
-structures that are directly involved with gas exchange
-begins where the terminal bronchioles join a respiratory bronchiole (smallest type)
-alveolar duct
-alveoli (simple squamous epithelium)
Where and how do O2 and CO2 exchange in the respiratory zone?
-passive diffusion through the simple squamous epithelium in the alveoli
-(non-polar molecules pass through the non-polar plasma membranes which are made of fat)
What do the alveoli include?
-alveolar duct (tube of smooth muscle and connective tissue)
-alveolus (one of the small sacs attached to the ducts)
-alveolar sac (cluster of individual alveoli)
Two main facts about lung tissue:
-majority is open space
-comprised of lots of connective tissue
Describe type I alveolar cells:
-simple squamous epithelium formed by these cells is attached to a thin, elastic basement membrane
-this epithelium is extremely thin and borders the endothelial membrane of capillaries
What is respiratory membrane?
-formed by the alveoli and capillary membranes
-0.5mm thick
-allows gasses to cross by simple diffusion
Describe the gross anatomy of the lungs:
-pyramid shaped
-connected to the trachea by the right and left bronchi
-bordered by the diaphragm on the inferior surface
What are the lungs enclosed by?
-pleurae (serous membrane) which are attached to the mediastinum
Why do the lungs require blood from pulmonary circulation to perform their function?
-blood supply contains deoxygenated blood and travels to the lungs where erythrocytes pick up oxygen to be transported to other tissues
Describe the process of pulmonary circulation:
-pulmonary artery arises from the pulmonary trunk and carries deoxygenated arterial blood to the alveoli
-the pulmonary branches into smaller and smaller branches until it forms the pulmonary capillary network
-the capillaries become so thin that when they reach to alveolar wall, the respiratory membrane is created
-after gas exchange occurs, it drains through pulmonary veins, which exit the lungs through the hilum
What is the difference between the visceral pleura and the parietal pleura?
-visceral pleura lines the lungs
-parietal lines the visceral
What is the the pleural cavity?
-the space between the visceral and parietal pleura that contains pleural fluid
-this allows the lungs to expand and contract smoothly by reducing friction
Which cells secrete pleural fluid?
-mesothelial cells
What is pulmonary ventilation?
-the mechanical act of breathing by moving air in and out of the lungs
What are the major mechanisms that drive pulmonary ventilation?
-atmospheric pressure
-alveolar pressure
-intrapleural pressure
What is intrapleural pressure?
-the pressure of the air within the pleural cavity
-approximately -4 mmHg throughout breathing cycle
What is transpulmonary pressure?
-the difference between the intrapleural and intra-alveolar pressures
-determines the size of the lungs
-higher transpulmonary pressure=larger lung
Name some physical factors that affect breathing:
-the contraction and relaxation of muscle fibers of the diaphragm and thorax
-the adhesive nature of pleural fluid allows the lungs to be pulled outward during inspiration
-recoil of the thoracic wall compresses the lungs
-most pressure changes caused by diaphragm and intercostal muscles
In which direction does air flow?
-from areas of higher pressure to areas of lower pressure
Which is greater: intra-alveolar pressure or intrapleural pressure?
-intra-alveolar
Which muscle groups are used during inspiration?
-diaphragm
-external intercostal
What causes expiration?
-expiration is passive-does not require energy
-elasticity of the lung tissue
-relaxation of the diaphragm and intercostal muscles
-interpulmonary pressure becomes higher than atmospheric pressure