Endocrine System Flashcards
Name the origin, destination, and control of Thyroid Stimulating Hormone
-Anterior Pituitary
-Thyroid
-Stimulate production of T4 and T3
Name the origin, destination, and control of Adrenocorticotropic Hormone
-Anterior pituitary
-Adrenal cortex
-Cortisol secretion
Name the origin, destination, and control of Follicle-Stimulating Hormone
-Anterior pituitary
-Ovaries/testes
-Ovarian follicle growth & spermatogenesis
Name the origin, destination, and control of Luteinizing Hormone
-Anterior pituitary
-Ovaries/testes
-Ovulation/testosterone secretion
Name the origin, destination, and control of Growth Hormone
-Anterior pituitary
-All tissues
-Growth/carbohydrate, protein, & fat metabolism
Name the origin, destination, and control of Prolactin
-Anterior pituitary
-Mammary gland
-Milk secretion
Name the origin, destination, and control of Anti-Diuretic Hormone
-Posterior pituitary
-Kidneys
-Water retention/blood pressure
Name the origin, destination, and control of Oxytocin
-Posterior pituitary
-Uterine smooth muscle & mammary gland
-Uterine contractions/milk release
Name the origin, destination, and control of Thyroxine (T3 & T4)
-Thyroid
-Most tissues
-Metabolic rate/growth/development
Name the origin, destination, and control of Calcitonin
-Thyroid
-Bone
-Lower plasma calcium and phosphate
Name the origin, destination, and control of Parathormone
-Parathyroid
-Bone/kidneys/intestine
-Elevate plasma calcium and phosphate
Name the origin, destination, and control of Cortisol, Cortisone, and Corticosterone
-Adrenal cortex
-All tissues
-Metabolism/response to stress and exercise
Name the origin, destination, and control of Aldosterone
-Adrenal cortex
-Kidneys
-Sodium, potassium, and pH balance
Name the origin, destination, and control of Epinephrine/Norepinephrine/Adrenaline
-Adrenal medulla
-All tissues
-Metabolism/heart rate & output/response to stress and exercise
Name the origin, destination, and control of Insulin
-Pancreas (Islets of Langerhans/beta cells)
-Muscle and liver
-Lowering blood sugar
Name the origin, destination, and control of Glucagon
-Pancreas (Islets of Langerhans/alpha cells)
-Liver
-Elevating blood sugar
Name the origin, destination, and control of Testosterone
-Testes
-Reproductive organs
-Reproductive development/behaviour
Name the origin, destination, and control of Estrogen
-Ovaries
-Reproductive organs
-Reproductive development and behaviour
Name the origin, destination, and control of Progesterone
-Ovaries
-Uterus
-Uterine condition
Name the origin, destination, and control of Melatonin
-Pineal gland
-Various tissues
-Circadian rhythm, reproduction
Name the origin, destination, and control of Thymosin
-Thymus
-T-lymphocytes
-Immune responses
What is the difference between exocrine and endocrine glands?
-Exocrine glands secrete substances into a ductal system to an epithelial surface
-Endocrine glands secrete products directly into the bloodstream
Describe the renin-angiotensin-aldosterone system:
- Drop in BP triggers JGA to secrete renin
- Renin converts angiotensinogen to angiotensin I
- Angiotensin-Converting Enzyme (ACE) in lung capillaries converts angiotensin I to angiotensin II
- Angiotensin II circulates to adrenal cortex and triggers secretion of aldosterone
- Aldosterone causes kidney to retain sodium and water, increasing BP
What are the three layers of the adrenal cortex?
-Zona glomerulosa (secretes mineralocorticoids)
-Zona fasciculata (secretes glucocorticoids)
-Zona reticularis (secretes gonadocorticoids)
What is the endocrine portion of the pancreas called?
Islets of Langerhans
What are the five primary types of endocrine cells in the pancreatic islets?
- alpha cells (secrete glucagon)
- beta cells (secrete insulin)
- delta cells (secrete somatostatin)
- epsilon cells (secrete ghrelin)
- pancreatic polypeptide cells (secrete pancreatic polypeptide)
How does a healthy body regulate low blood sugar?
-Low blood sugar detected
-Increased glucagon production by alpha cells
-Decreased insulin production by beta cells
-Glucose release by liver increases
-Glucose uptake by cells decreases
-Glucose levels in blood increase
How does a healthy body regulate high blood sugar?
-High blood sugar detected
-Increased insulin production by beta cells
-Decreased glucagon production by alpha cells
-Glucose uptake by cells increases
-Glucose release by liver decreases
-Glucose levels in blood decrease
What does adren/o and adrenal/o mean?
Adrenal gland
What does hypophys/o mean?
Pituitary gland
What does oophor/o and ovari/o mean?
Ovary
What does orch/o and orchid/o mean?
Testes
What does pancreat/o mean?
Pancreas
What does parathyroid/o mean?
Parathyroid gland
What does pituitary/o mean?
Pituitary gland
What does thyroaden/o and thyroid/o mean?
Thyroid gland
What is acromegaly?
Enlargement of extremities caused by hypersecretion from the anterior portion of the pituitary gland after puberty
What is Cushing syndrome?
Group of clinical features produced by excess secretion of cortisol from the adrenal cortex, including obesity, moon-face, hyperglycemia, osteoporosis
What is diabetes mellitus?
Disorder of the pancreas that causes hyperglycemia. Type I onsets in childhood and is characterized by a complete deficiency of insulin. Type II onsets in adulthood and is a deficiency/resistance to insulin
What is a goiter?
Enlargement of the thyroid gland
What is hyperthyroidism?
Overactivity of the thyroid gland
What is exophthalmometry?
Measurement of eyeball protrusion (exophthalmos) as an indicator of hyperthyroidism
What is a fasting blood sugar test?
Measurement of glucose levels in a blood sample taken from a fasting patient, and in specimens taken 30min, 1hr, 2hr, and 3hr after ingesting 75g of glucose
What is radioactive iodine uptake?
Measurement of how much of a radioactive element (iodine) is absorbed by the thyroid gland
What is serum and urine tests?
Measurement of hormones, electrolytes (eg K and Na) and glucose levels in serum and urine as indicators of endocrine function
What is thyroid function tests?
Measurement of levels of T4, T3, and TSH in the bloodstream
What is thyroid scan?
An intravenously intaken radioactive element localizes in the thyroid gland and a scanning device reveals any tumors or nodules
What does ACTH mean?
AdrenoCorticoTropic Hormone
What does DM mean?
Diabetes Mellitus
What does GH mean?
Growth Hormone
What does GTT mean?
Glucose Tolerance Test
What does HbA1c mean?
Hemoglobin A1c measures the average amount of glucose in red blood cells
What does RAIU mean?
RadioActive Iodine Uptake
Identify the gland depicted here and specify the circled part
Pituitary gland, anterior
Identify the gland depicted here and specify the circled part
Pituitary gland, posterior
What is depicted in this image and what type of epithelial tissue is visible?
Follicular cells in the thyroid, simple cuboidal epithelium
What is being indicated by the arrow in this image?
Adipose cells in the parathyroid gland
What is being indicated by the arrow in this image?
Cortex of the adrenal gland
What is being indicated by the arrow in this image?
Medulla of the adrenal gland
What is depicted in this image?
An Islet of Langerhans in the pancreas
What type of epithelial tissue is shown here?
Simple cuboidal epithelium