Respiratory - histology Flashcards

1
Q

Describe respiratory epithelium

A

Pseudostratified columnar epithelium ciliated with goblet cells

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2
Q

Function of the nasal cavity

A

to produce space for warming, moistening, and filtering inspired air

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3
Q

Where is specialised olfactory epithelium found

A

Roof of the nasal cavity

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4
Q

What lines the vestibule of the nasal cavity

A

keratinised stratified squamous epithelium

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5
Q

What is underneath the respiratory epithelium of the nasal cavity (3)

A

Lamina propria
Loose connective tissue band containing seromucous glands
Thin-walled venous sinuses

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6
Q

What do the walls of the larynx consist of (3)

A

cartilage
Muscle
Respiratory epithelium

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7
Q

What is the trachea composed of (2)

A

C-shaped cartilages
With gap spanned by fibro-elastic tissue and smooth muscle

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8
Q

What is beyond the respiratory epithelium of the trachea (3)

A

basal lamina
Lamina propria
Submucosa

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9
Q

How are the bronchi different histologically from the trachea

A

the cartilages are irregular rather than C shaped

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10
Q

What do the walls of the bronchi consist of (3)

A

respiratory epithelium
Lamina propria
Muscularis

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11
Q

Describe the Muscularis of bronchi walls (4)

A

Ring of smooth muscle with
Adipose tissue
Submucosa
Seromucous glands

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12
Q

Bronchiole histology (3)

A

epithelium goes from columnar to cuboidal
May contain goblet cells
Lack cartilage

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13
Q

What is the lamina propria of bronchioles composed of (3)

A

smooth muscle
Elastic fibres
Collagenous fibres

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14
Q

What are terminal bronchioles (2)

A

The smallest bronchioles
Lack respiratory function

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15
Q

How do bronchioles respond to parasympathetic inner action

A

Smooth muscle contraction leads to Constriction of bronchiole

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16
Q
A
17
Q

What unique type of cell do terminal bronchioles contain

A

non-ciliated club cells
Which project above layer of ciliated cells

18
Q

Going from bronchioles to alveoli, what change happens

A

cuboidal epithelium is replaced by discontinuous squamous type I alveolar cells

19
Q

What are the types of epithelial cells of alveoli (2)

A

type I alveolar cells - simple squamous epithelium
Type II alveolar cells - polygonal cells

20
Q

Function of type II alveolar cells (3)

A

Reducing tendency for alveoli to collapse after expiration
release surfactant via exocytosis
This surfactant spreads over pulmonary surface to reduce surface tension at air-fluid interface

21
Q

Where is surfactant found in type II alveolar cells

A

cytoplasm, in membrane-bound lamellar bodies

22
Q

Which type of alveolar cell is more abundant

A

type I

23
Q

What other type of cell (not epithelial) do alveoli contain

A

alveolar macrophages

24
Q

Describe action of alveolar macrophages (3)

A

phagocytose inhaled particles
Transported by ciliary action to pharynx
Are swallowed/move into septal connective tissue

25
Q

What are lung surrounded by (and what is this made of 2)

A

visceral pleura
(Mesoepithelium backed by fibrous and elastic connective tissue)

26
Q

What structures are alveoli associated with (3)

A

Respiratory bronchioles
Alveolar ducts
Alveolar sacs

27
Q

describe the conducting portion of the airway (2)

A

Extends form trachea to terminal bronchioles
No gas exchange occurs with blood

28
Q

.

A

.