Respiratory Drugs: Bronchodilators

Question 1

What do bronchodilators do?

Answer 1

Drugs that relieve bronchoconstriction​

Question 2

What does this cause?

1. parasympathetic nervous system stimulation​
2. histamine release​
3. prevention of sympathetic nervous system stimulation​

Answer 2

bronchoconstriction

Question 3

What does this cause?

1. organophosphate or carbamic in high doses
2. the drugs bind to acetylcholinesterase and acetylcholine will continue to stimulate this

Answer 3

parasympathetic nervous system stimulation

Question 4

What causes this?

1. histamine receptors on smooth muscle
2. allergies leading to massive histamine release

Answer 4

bronchoconstriction

Question 5

What bronchodilator is this?

1. terbutaline, clenbuterol, albuterol, metoproterenol)​
2. stimulate sympathetic nervous system receptors (β-2) involved in bronchodilation and stabilization of mast cells​
3. available in inhalant, oral, and injectable formulations​

Answer 5

Beta-adrenergic agonists

Question 6

What bronchodilator is this?

1. aminophylline, theophylline
2. causes bronchodilation by interfering with smooth muscle cell metabolism​
3. may cause CNS stimulation and GI upset​
4. have narrow therapeutic range​
5. metabolized in the liver by enzymes that metabolize many other veterinary drugs​

Answer 6

Methylxanthines