Cardiovascular Drugs: Antiarrhythmic Drugs Flashcards
1
Q
Definition of arrhythmia
A
an abnormal pattern of electrical activity in the heart
2
Q
What causes an arrhythmia?
A
Usually caused by a group of abnormal cells ➡️ depolarize on their own, not in conjunction w/ the SA node
3
Q
What do Antiarrhythmic Drugs prevent?
A
autodepolarization
4
Q
What type of antiarrhythmic drug is this?
- inhibit movement of sodium ions acrosscell membranes
- Licocaine
- Procainamide and quinidine
A
Sodium influx inhibitors
5
Q
What Sodium influx inhibitor is this?
- should be given IV
- large doses may cause sedation, ataxia, drowsiness
- cardiovascular shock and seizures occur w/ overdose
A
Lidocaine
6
Q
What Sodium influx inhibitor is this? (2)
- both available in oral form
- One can be given IM, IV
- cancause vomiting, diarrhea, anorexia, increase digoxin plasma levels
A
Procainamide and quinidine
7
Q
What type of antiarrhythmic drug is this?
- block movement of calcium across channels in the cell membrane
- may decrease heart contractility
- diltiazem, verapamil
A
Calcium channel blockers
8
Q
What type of antiarrhythmic drug is this?
- blocks sympathetic nervous system receptors, dec. contraction rate of the heart
- Propanolol
A
Beta Blockers
9
Q
What Beta Blocker has these adverse effects?
- decreases contractility
- bronconstriction
- abnormally slow HR
- lose effectiveness over time
A
Propanolol