respiratory drugs Flashcards

1
Q

defense mechanisms of the resp. system

A

turbinates, hiar, coughing, sneezing, spasms, mucus secretions, cilia, IgA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

3 principles of resp. therapy

A

control secretions, control reflexes, maintain airflow to alveoli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

how do we control secretions

A
  • production, + elimination, remove cause of secretion (antibiotics, antifungal, antiparasitic), make secretions less viscid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how do we control reflexes

A

suppress cough, control sneezing, control bronchospasms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

maintaining flow of alveoli

A

reverse bronchoconstriction, remove edema mucus, provide O2 therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

another name for aerosolization

A

nebulization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is aerosolization

A

allows delivery of drugs at high concentrations directly to airways with minimal blood level

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what factors affect distribution of drug

A

size of inhaled particles, must be 1-5 microns, presence of mucus or exudate, bronchodilator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

8 categories of resp drugs

A

expectorants, mucolytics, bronchodilators, decongestants, antihistamines, corticosteroids, misc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

expectorant

A

drugs that liquify and dilute viscous secretions (used for productive coughs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

example of expectorant

A

guaifenesin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

adverse effects of expectorant

A

few, nausea and drowsiness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

mucolytic

A

drugs that breaks down chemical structure of mucous viscosity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

example of mucolytic

A

acetylcysteine (nebulized) oral or iv used for acetaminophen toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

adverse effects of mucolytic

A

nausea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

antitussive

A

drug that suppresses cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

how does antitussive work

A

only used for non-productive cough, can be central or peripheral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

central acting antitussive

A

suppresses cough center of the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

peripheral-acting antitussive

A

cough drops, depress cough receptors in airways

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

example of antitussives

A

butorph, codeine, dextromethorphan, temaril-P, hydrocodone bitartrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

butorphanol

A

opioid CIV, analgesia

22
Q

side effects of butorphanol

A

sedation, ataxia

23
Q

hydrocodone bitartrate

A

opioid CII

24
Q

side effects of bitartrate

A

sedation, constipation, GI upset

25
Q

codeine

A

opioid CV

26
Q

side effects of codeine

A

sedation, constipation

27
Q

dextromethorphan

A

non-narcotic, similar to codeine, no analgesia or addictive prop.

28
Q

side effects of dextro

A

drowsiness and GI upset

29
Q

temaril-P

A

antitussive, corticosteroid

30
Q

side effects of temaril-P

A

sedation, depression, hypotension, minor CNS signs

31
Q

effect of PNS in respiratory

A

bronchoconstriction, + secretions

32
Q

effect of SNS in respiratory

A

bronchodilation, - secretions

33
Q

bronchoconstriction mechanisms

A

release of ACh in PNS reducing airflow, histamine response, or beta-2 blocker

34
Q

cholinergic blockers

A

bind to ACh receptors and block effects

35
Q

example of cholinergic blockers

A

atropine (preanesthetic), aminopentamide, glycopyrrolate

36
Q

beta-2 adrenergic agonists

A

beta-2= bronchioles
dilate bronchioles

37
Q

beta-2 agonists drugs

A

epinephrine (save for anaphylaxis), isoproterenol, albuterol, clenbuterol

38
Q

side effects of beta-2 agonists

A

tachycardia and hypertension

39
Q

methylxanthines

A

inhibit an enzyme in smooth muscle promoting bronchodilation, stimulate heart muscle

40
Q

methylxanthine drugs

A

aminophylline and theophylline (cat asthma) caffeine, theobromine

41
Q

adverse effects of mex

A

GI upset, CNS stim, tachycardia, ataxia, arrhythmia

42
Q

decongestants

A

decrease congestion of nasal passages

43
Q

antihistamine

A

block effects of H1

44
Q

antihistamine drugs

A

diphenhydramine, hydroxyzine, cetirizine

45
Q

adverse effects of antihistamine

A

sedation, GI upset

46
Q

corticosteroids

A

decrease inflammatory response or allergic respiration, equine obstructive pulmonary disease

47
Q

corticosteroids drugs

A

prednisolone, dexamethasone, beclomethasone dipropionate

48
Q

cats cannot convert____

A

prednisone

49
Q

misc drugs

A

antimicrobials, mast cell stabilizers, diuretics for pulm. edema, resp. stimulants

50
Q

naxolone

A

reverse opioids increase resp.

51
Q

yobine

A

reverse xylazine increase resp.