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Pharmacology > antiparasitic > Flashcards

antiparasitic Flashcards

1
Q

relationship where one animal benefits and the other is harmed

A

parasitic

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2
Q

parasites can be contracted by

A

animal to animal, ingestion, insects, direct contact with parasite

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3
Q

helminths are divided into 2 categories

A

nematodes (roundworm and hookworms) and platyhelminths (tapeworms and flukes)

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4
Q

work by interfering with energy metabolism of worm

A

benzimidazoles

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5
Q

has antifungal and anti inflammatory effect

A

thiabendazole

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6
Q

wide spectrum of activity given for 3 ys

A

fenbendazole

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7
Q

generic name for valbazen

A

albendazole

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8
Q

stimulate nematodes cholinergic nervous system leading to paralysis

A

imidazothiazoles

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9
Q

example of imidazothiazoles

A

levamisole

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10
Q

mimic action of ACh and cause paralysis to ascarids, pinworms, and strongyles and hookworms

A

tetrahydropyrimidines

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11
Q

examples of tetrahydropyrimidines

A

pyrantel pamoate (Nemex, Strongid) pyrantel tartrate, and morantel tartrate

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12
Q

strongid is affected against

A

hooks and rounds

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13
Q

bind to certain channels in the parasite nerve and muscle cells causing paralysis and death, heartworms and mange

A

avermectins (macrocyclic lactones)

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14
Q

examples of avermectins

A

ivermectin, moxidectin

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15
Q

breeds sensitive to ivermectin

A

collies, sheepdogs, and mixes

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16
Q

blocks neuromuscular transmission in the parasite, only against ascarids

A

piperazine

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17
Q

increases cestodes cell membrane permeability (disintegrates) can also be used on fleas

A

praziquantel

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18
Q

disintegration of cestode (taenia and dipylidium)

A

epsiprantel

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19
Q

only effective against taenia species

A

fenbendazole

20
Q

suffix for tapes

A

-antel

21
Q

works by inhibiting trematodes enzyme systems for energy production (fasciola hepatica)

A

clorsulon

22
Q

interferes with energy metabolism of trematode

A

albendazole

23
Q

effective against lung trematodes in dogs and cats

A

praziquantel

24
Q

topical antiparasitic stimulate presynaptic receptors, paralysis, and death

A

depsipeptides

25
Q

trade name; topically for cats treating hook, round, and tape

A

profender

26
Q

SE profender

A

lethargy, salivation, vomiting, neuro signs

27
Q

protozoal infection that causes intestinal disorders

A

coccidiosis

28
Q

reduces number of oocytes shed by cocci

A

sulfadimethoxine (Albon)

29
Q

neuro disease in horses caused by S. neurona

A

myeloencephalitis

30
Q

Tx for myeloencephalitis

A

Ponazuril (Marquis)

31
Q

ponazuril can also be used for

A

toxoplasma spp, coccidia, and neospora caninum

32
Q

protozoal disease caused by Giardia

A

giardiosis

33
Q

drugs that treat giardiosis

A

metronidazole, febendazole, albendazole

34
Q

drugs for Babesia sp. from ticks

A

imidocarb

35
Q

heartworm disease is caused by

A

dirofilaria immitis

36
Q

managing hw disease

A

prevention, adulticide therapy, eradication

37
Q

oral hw preventatives

A

ivermectin, milbemycin

38
Q

topical hw preventatives

A

selamectin, moxidectin

39
Q

6-12 month injectable hw prevention

A

moxidectin

40
Q

adulticide hw therapy

A

melarsomine (given in epaxial)

41
Q

bravecto

A

fluoliner chews; administered every 12 weeks, reaches tissue fluids so when fleas and ticks feed, they die

42
Q

NexGard

A

afoxolaner; stimulates fleas nervous system causing them to rise to top of dogs coat and they die

43
Q

advantix

A

imidacloprid and permethrin; topical solution for flea, ticks, mosquitoes, and flies

44
Q

advantage II

A

imidacloprid; kills adults, larvae, and eggs, kills on contact

45
Q

Frontline, TopSpot, Fiproguard

A

fipronil; fight fleas and ticks

46
Q

comfortis

A

spinosad (flea and tick)

47
Q

capstar

A

nitenpyram (flea and tick)

Pharmacology (14 decks)

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