Respiratory Distress In Newborn

Question 1

RDS?

Answer 1

RR >60
Increase work of breathing
noisy breathing: grun: strider, wheeze
Central cyanosis

Question 2

Causes of RDS?

Answer 2

#1 Sepsis/pneumonia: #1 - most dangerous
#2 Wet Lung/TTN- #2 -most common

Question 3

TTN?

Answer 3

Transient tachypnoea of the newborn

Question 4

Cause of TTN?

Answer 4

Continued production of delayed removal of fetal lung liquid, will get better on own, but will have supportive Rx.

Question 5

MAS?

Answer 5

Meconium aspiration syndrome

Question 6

Why MAS bad?

Answer 6

Chemical pneumonitis

Infection on top of it.

Question 7

Why diaphragmatic hernia, so unwell?

Answer 7

Underdeveloped lungs, severe pulmonary hypertension

Question 8

Clues to neonatal sepsis?

Answer 8

Mother sick? Chorioamnionitis?

Spontaneous labour

Question 9

Most common causes of preterm distress?

Answer 9

1. Sepsis

2. RDS/hyaline membrane disease

Question 10

RDS cause?

Answer 10

Lack of surfactant in lung

Question 11

Secondary RDS?

Answer 11

MAS, inactivated

Question 12

Surfactant production started/caused by?

Answer 12

Cortisol surge in 34-35 weeks

Question 13

Where is surfactant created?

Answer 13

Type 2 pneumocytes

Question 14

RDS

Answer 14

DM2 mothers
Males
Second twin
FHx

Question 15

Surfactants prevent?

Answer 15

prevent long term Chronic lung disease

Caffeine to reduce BPD

Question 16

Target O2 in preterm? Too little vs. Too much?

Answer 16

91-95%

Survival vs. Retinopathy of prematurity

Question 17

How to give surfactant?

Answer 17

Directly through intubation