Hypertension In Preg Flashcards

1
Q

Preeclampsia is?

A
Syndromic
Pregnancy induced
HTN
Proteinuria
Generalized oedema
Multi system dysfunctions
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2
Q

Preg HTN defined as?

A

> 140/90

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3
Q

Preeclampsia definition

A

HTN - >140/90 of 170/110
Proteinuria >300mg/24h
Generalised oedema

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4
Q

3 most important causes of proteinuria

A

Artifact-leukoruria from cervix
UTI
Preeclampsia

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5
Q

How to ask about preeclampsia to family?

A

Any difference in appearance? (Swollen face)

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6
Q

How to manage preeclampsia?

A

Premature delivery

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7
Q

How to cure preeclampsia?

A

Deliver the baby and placenta!

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8
Q

Preeclampsia affects What system?

A
Cardiovascular
Renal
Haematologic all
Neurological
Hepatic
Uteroplacental
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9
Q

Symptoms for preeclampsia occurs?

A

LATE.

Very asymptomatic

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10
Q

Predisposing to preeclampsia?

A
FHx
Age extremes
First preg
New paternity
period of Sexual cohabitation (more antigen exposure)
Assisted reproduction
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11
Q

Medical comorbidities that increase preeclampsia?

A
Chronic HTN
SLE
DM2
Disease
Thrombophilias
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12
Q

Predisposing pregnancy conditions for preeclampsia?

A
Size of placenta from
Multiple preg
Gestational DM2
Trophoblasts disease
Hydrops Fetalis

Trisomy13

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13
Q

Indicators of severe preeclampsia?

A
extreme HTN
Headache
Papillon edema
Visual disturbance
Upper Abdo pain
Hyper reflexes
Oliguria
Proteinuria
Thrombocytopaenia
Pulmonary oedema
Elevated liver enzymes
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14
Q

Management of HTN?

A
Admit
Stabilize
BP control
Seizure prophylaxis
Fluids
Fetal welfare surveillance
Multidisciplinary care
DELIVERY
Third stage management (drug to minimize bleeding - no longer ergometrine, now: -Syntocinon-)
Postpartum observation
Followup
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15
Q

Pre-eclampsia is cured when?

A

AFTER delivery. Not AT delivery, need postpartum observation

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16
Q

Post partum observation indicators

A

Look at urine output. If increasing:

Kidneys working, recovering,

17
Q

Preeclampsia HTN management pharma?

A

Labetalol

Nifedipine

18
Q

Neuronal stabilization in Preeclampsia pharma?

A

MgS04 syringe pump 4g bolus over 15 minutes
2g/HR maintenance
Monitor reflexes, Resp, serum levels, urine output
Continue 24 hours postpartum
The MAGPIE trial.

19
Q

Antidote for MgS04 if the woman Preeclampsia stops breathing

A

CaCl2. 10ml, 10%

20
Q

MgS04 effects in preterm fetus?

A

Less likely to have cerebral palsy
Will give at less than 30 weeks gestation, close to 4 hours before birth or within 24 hours of expected birth
Give to mother

21
Q

Preeclampsia delivery favoring vaginal?

A
Multiparous mother
Cerebral BP
Ripe cervix
Mature fetus
Cephalic presentation
22
Q

Preeclampsia delivery route favoring c section

A
Miparous mother
Unstable BP
Cerebral irritability
Un ripe cervix
Immature fetus
Breech
IUGR
Abnormal Doppler
23
Q

Most common reason for grand-mal seizure in preg?

A

Epilepsy

24
Q

How to distinguish epilepsy from Preeclampsia?

A

Bracelet of epileptic woman
Look in handbag for Meds
Gum hypertrophy

25
Q

Version of Preeclampsia affecting liver/haematologic all

A

HELLP syndrome

Haemolysis elevated Liver Enzymes Low Platelet Count

26
Q

DDx HTN in preg?

A

Chronic HTN
Endocrine: phaeo
Cushing
Renal htn

27
Q

Only treatment to prevent Preeclampsia?

A

Low dose Aspirin

CLASP Trial

28
Q

Theory of Preeclampsia?

A

Poor placenta growth into the decidua, the arterioles still have smooth muscle, can contract raising BP