Infectious Disease In Preg Flashcards
Perinatal infections?
Herpes simplex
Postpartum infection
Pertussis
Vertical transmission
In utero
In Breast milk: HIV
Incubation of varcella
2 weeks
Complications of varicella?
Pneumonitis In adults
SEcondary bacterial infection
When is maternal death most common in varicella?
3rd trimester
Congenital varicella syndrome?
Shingles in utero Short limbs Microcephalic Scarring Mental retardation GIT, GU abnormalities
Wen give prophylactic VZIG?
-Post exposure (
Can give varicella vaccine in preg?
Nope - live vaccine
CMV in fetus?
Microcephalic
IUGR
CMV serology probs?
IgM is detectable for months
Deactivation will detect IgM
Need to do avidity testing or past serum
Baby asymptomatic at birth for CMV how detect?
Audiometry
Visual
Pneumonitis
Microcephalic
Rx of CMV?
Gancyclovir
Influenza and preg deaths mainly from?
Premature birth
Early and late fetal death
Most probs happen when with influenza?
3rd trimester
Group B strep
Purple G-neg in chains like a ‘rockstar’
GBS infection how?
- Ascending infection
2. At delivery
Early onset GBS when? Presents?
1-2 days after birth
Pneumonia, less common meningitis
Late onset GBS?
meningitis more likely
Abx for GBS?
- 4 hours prior to delivery
- BenPen
- Ampicilin
-Clindamycin/vancomycin if allergy
Prophylaxis for GBS how good?
80%
Primary casuse of EOS?
GBS
When screen for GBS?
Screen at 35-37 weeks
When does vertical transmission happen in Hep B?
During labour and birth
E antigen +ve = 90%
E antigen -ve =
When give HBIG to baby?
Within 12 hours
Hep C vertical transmission%?
5% if higher viral load
Co-infected with HIV = 45%
Hep C Rx for preg?
Contraindicated
Can breast feed with Hep C?
Nope
When check Hep C in baby?
12-18 months
Parvovirus when infectious?
Before the rash
Parvoviruses can get what in utero?
Red cell aphasia if have thalassemia
Fetal Hydrops - Anaemia, cardiac failure, oedema
Parvovirus investigation?
SErology
If positive Parvovirus in mom, then what?
U/S every week for 12 weeks
Rubella rash lasts?
2 and 3 days
Rubella presents?
Lymphadenopathy: occipital node chains (95%)
Arthritis large joints
Rubella in >12 weeks
Retinopathy and deafness only
When rubella most damaging in utero?
1st trimester
Fetal rubella detection?
Amniotic fluid
Cord blood