Respiratory Flashcards

1
Q

anatomic dead space

A

any part of the RT that does not exchange gases

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2
Q

cartilage and goblet cells extend to

A

end of bronchi

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3
Q

ciliae and smooth muscle extend to

A

end of terminal bronchii

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4
Q

histology of respiratory broncholes

A

cuboidal, then simple sqaumaous to alveoli

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5
Q

purpose of alveloar macrophages

A

clear depris and participate in immune response

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6
Q

line most of alveolar surfaces

A

type 1 pneumocytes

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7
Q

extrete pulmonary surfacant

A

type II pneumocytes

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8
Q

cells that proliferate in lung damage

A

type II pneumocytes

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9
Q

collapsaing pressure calculation

A

P= 2xsurface tension/radius

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10
Q

most important protein in pulmonary surfacant

A

dipalmitolphosphaatodylcholine

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11
Q

beginning of surfacant production in utero

A

week 26 (fully mature at 35)

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12
Q

indicates fetal lung maturity

A

lectin to sphingmelin ratio of > 2.0

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13
Q

lung with 3 lobes

A

right (what would be the middle lobe in the left has the heart instead)

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14
Q

lung with lingula

A

left

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15
Q

where a peanut is going to go

A

lower portion of right

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16
Q

where the IVC passes diaphram

A

T8

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17
Q

where the eosophagus passes diaphram

A

T10

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18
Q

where the aorta passes diaphram

A

T12

19
Q

inervates the diaphram

A

phrenic nerve (from C3,4,5)

20
Q

air that can be breathed in after normal respiration

A

inspiratory reserve

21
Q

air that moes into lung with each quiet resp

A

tidal volume

22
Q

air that can still be breathed out after normal exp

A

exiratory reserve

23
Q

air in lung after max expiration

A

residual volume

24
Q

inspiratory capacity

A

IRV+TV

25
Q

FRC

A

RV+ERV

26
Q

VC

A

TV+IRV+ERV

27
Q

total ling capacity

A

IRV+TV+ERV+RV

28
Q

largest contribultor of functional dead space

A

apex of healthy lung

29
Q

def of compliance

A

change in lung volume with change in pressure

30
Q

conditions with lower lung compliance

A

pulmonary fibrosis, edema and pneumonia

31
Q

conditions with higher lung complience

A

emphyseme and normal aging

32
Q

shifts o2 disassociation curve to right, leading to unloading

A

CO2, 1,2-BPG, exersize, acid/altitde, temp

33
Q

oxidised hemoglobin that binds to cyanide

A

methemoglobin (can be caused by nitrite poisoning)

34
Q

left shifts hemoglogbin (decreases o2 unlodaing in tissues)

A

CO (200x greater oxygen binding ability)

35
Q

signs of right heart failure

A

JVD, edema, hepatomegaly

36
Q

causes primary pulmonary hypertension

A

inactivating mutation if BMPR2 gene that lets vascular smooth muscle hyperproliferate

37
Q

causes secondary pulmonary hypertension

A

COPD, mitral stenosis, recurrent thromboemboli, autoimmune dx, left to right shunt, altitude

38
Q

area of lung with greatest ventilation and perfusion

A

base

39
Q

highest O2 content in lung

A

apex

40
Q

V/Q approching zero indicates

A

airway obstruction

41
Q

V/Q approching infinity ndicates

A

blood flow obstruction to lung

42
Q

most CO2 transported back to lungs in form of

A

bicarbonate

43
Q

bohr effect

A

in peripheral tissue, increased H+ from tissue metabolism pushes O2 dissacoation curve to right, causing unloading od O2