endocrine Flashcards

1
Q

most common site of ectopic thyroid tissue

A

tounge

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2
Q

anterior midline neck mass that moves with swallowing

A

thyroglossal duct cyst

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3
Q

secrets aldosterone

A

zone glomerulosa (outer adrenal cortex)

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4
Q

secrets cortisol and sex hormones

A

zona fasisculata (middle adrenal cortex)

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5
Q

secretes androgens

A

zona reticulalaris (inner adrenal cortex)

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6
Q

secretes catccholamines

A

adernal medulla

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7
Q

drains into IVC via renal vein

A

left adrenal gland

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8
Q

posterior pituitary secretes

A

ADH and oxytocin

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9
Q

anterior pituitary secretes

A

FSH, LH,ACTH, TSH,prolactin, GH, melanotropin

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10
Q

alpha pancreas cells release

A

glucagon

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11
Q

delta pancreas cells release

A

somatpstain

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12
Q

expresses GLUT-1

A

RBC’s, Brain

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13
Q

insulan dependant GLUT receptors

A

4 (on adipose and skeletal muscle)

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14
Q

anabolic functions of insulin

A

glucose transport into skeletal muscle and adipose

glycogen and TG synth/storage

Na retention
Protein synth
cellular uptake of K+ and amino acids
glucagon release

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15
Q

always dependant for glucose

A

RBCs (lack mitochondira for anerobic metabolism)

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16
Q

catabolic effects of glucogon

A

glycogennolysis, gluconeogenisis, lipilysis and ketone production

17
Q

downregulates prolactin

A

dopamine

18
Q

downregulates GH and TSH

A

somatostatin

19
Q

downregulates GnRH

A

prolactin

20
Q

17a-hydroxylase deficiency presents

A

high mineralcorticoids, low cortisol, low sex hormones

hypertension, hypokalemia

21
Q

XY with low DHT

A

pseudohermaphroditism

22
Q

XX with 17a-hydroxylase deficiency

A

external phenotypical female with normal internal sex organs, lacking secondary sex charecteristics

23
Q

21 hydroxalase deficiency (most common) presents as

A

low mineralcorticoids, low cortisol, high sex hormones

hypotension, hyperkalemia, hi renin and volume depletion

masculization, eading to pseudoherm in females

24
Q

11B - hydroxylase def presents as

A

low aldosterone, low cortisol, high sex hormones.

hypertension and msculizization

25
Q

cortisol effects

A
maintains BP
lowers bone formation
anti inflammatory
immunosuppressive
raises insulin resistance
increases gluconeoenisis, liposyisis, 
inhibits fibroblasts (striae)
26
Q

function of PTH

A

increases serum calcim

decreses phosphate reabsorption in DCT

27
Q

secretes calcitonin

A

parafolicular (C cells) of thyroid

28
Q

function of calcitonin

A

opposes PTH, lowers serum Ca++