Respiratory Flashcards
Rx for pulmonary AH
bosentan
Bosentan MOA
competitive antagonist of endothelin-1 receptor
Methacholine vs
ipratropium (M3 receptor blocker)
thoracocentesis rules
above 7, 9, 11
cyanosis, chocolate colored blood, dusky skin
methhemoglobinema
cyanosis happens when deoxy Hb is
mt 5g/dl
normal A-a gradient
10-15 mm Hg
conditions of hypoxemia with nl A-a gradient
alveolar hypoventillation (high altitude and opioid use)
life threating epistaxis which A
sphenopalatine A (branch of maxillary)
lines of Zahn is seen if thrombi are formed ….
before death
pulmonary emboli blood picture
resp alkalosis
Increased pH
Decreased PO2 and PCO2
mech of rash in fat emboli
thrombocytopenia leading to petcheial rash
obstructive characteristic
decreased FEV1/FVC ratio
4 drugs causing restrictive lung disease
bleomycin, busulfan, amiodarone and MTX
reticulo nodular opacitiy in CXR
interstitial lung disease (honey coomb lung )
only one body in pneumoconiosis
asbestos body (ferruginous) golden brown looks like dumbells
pathognomonic of asbestosis
pleural plaques
berylliosis
airplane granuloma
coal worker
black lung
Berryliosis risk
TB and Cancer
lobe predilection for pneumoconiosis
asbestosis - lower lobe (all else upper lobe)
gold std for asbestosis
EM (asbestosis fibres)
acid base in neonatal RDS
metabolic acidosis
in obesity, even at walking hours, PaCO2 is ….
increased (retention)
Rx for idiopathic PAH
bosentan (endothelin receptor antagonist)
Lung transplantation
extended consumption of fenfluramine is associated with
PAH
fremitus increased only in
consolidation
secondary spont pneumothorax due to
diseased lung or mech vn
cold agglutinin pneumonia
mycoplasma
lung abscess rx
clindamycin
paraneoplastic cerebellar degeneration
small cell ca
squamous and small cell ca are
central and smokers
Rx for small lung ca
chemotherapy (always)
mucin + lung ca
adenoca (copious secretion)
ca of non-smokers
adenoca (MC ovaerall)
large cell ca secrete
beta hCG (large breast and galactorrhoea)
2nd gen anti-histamine cause less sedation because
don’t cross BBB
mucous thinners
quaifenesin & NAC
omalizumab receptor
IgE
toxicity of theophylline and Rx
cardio and neuro (give beta blockers)
bronchiolitis obliterans
c/c transplant rejection