Reproductive Flashcards by Shajo kunnath

name of first arch syndrome

treacher collins syndrome

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which pouches in diGeorge syndrome

3rd and 4th pouches

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male is a meso-

wolf

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female is a para-

mulla

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lady makes

testosterone

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sertoli makes

MIF, inhibin, androgen binding protein

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5a reductase converts

testosterone to DHT

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hypo and epi spadiasis

hypo : urethral folds fail to fuse

epi: faulty positioning of genital tubercle

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clomiphene citrate and risk of ovarian ca

increases

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clomiphene MOA

antagonist of estrogen receptors in hypothalamus

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tamoxifen vs. raloxifene

tamoxifen agonist at uterus (increase ca risk)

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tamoxifen and raloxifene indications

tam for breast ca and ral for osteoporosis

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finasteride MOA

5a reductase inhibitor

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bhCG changes in pregnancy

double every 1.5 to 2 days (6-7 wk)

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VACTERAL defect which derm

mesoderm

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fetal hydantoin syndrome

cleft palate, heart defect

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abruptio placenta which street drug

cocaine

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SE of smoking on preg

IUGR

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preg defect in DM

caudal regression syndrome

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features of fetal alcohol syndrome

smooth philtrum, hypertelorism, heart lung fistula, holoprosencephaly

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vitteline and allantoic duct

vitelline: yolk sac to intestine (aka omphalo-mesenteric)
allantoic: yolk sac to bladder (aka urachus)
food is vital

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2nd arch issue

congenital pharyngo-cutaneous fistula

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cleft lip vs palate

lip: medial nasal process and maxillary
palate: lateral palatine process

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remnant of mesonephric duct

gartner’s duct

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mullerian agenesis is associated with

renal defect

external genitalia and prostate which hormone

DHT

uretral damage in pelvic # vs straddle

membranous (fracture) vs. penile

pudental block root

s2-s4

for treating infertility, menotropin (FSH) followed by

beta hCG (mimic LH surge)

menopause lab finding

``` decreased estrogen (estrone nl) Increased androgen, FSH, L, GnRH ```

Balding and BPH which hormone

DHT

Klinefilter syndrome is like ....

testicular failure (estrogen is high)

Turner: can be pregnant with

oocyte donation

maternal virilization

aromatase def

complete mole due to

complete paternal origin

hyperemesis and pre-eclampsia which mole

complete

triad of pre-eclampsia

HTN proteinuria edema

complication of HELLP

hepatic subcapsular hematoma

painful bleeding

abruption (previa is painless)

worse prognosis gynaec tumor

ovarian (then cervical)

basic pathology of PCOS

insulin resistance leading to increased FSH and LH | And then increased androgen

PCOS risk

endometrial ca

Rx for PCOS

weight reduction and OCP | Clomiphene if want to conceive

follicular cyst vs theca lutein cyst

``` follicular (single most common) theca lutein (B/L multiple) ```

ovarian tumor: principles

ovulation not good OCP, preg, lactation: good clomiphene, nulliparity: bad

dermoid cyst as

mature cystic teratoma

brenner tumor looks like

bladder

fibroma of ovary think about

meig syndrome and pulling sensation

MC uterine malposition

retroversion

MC stromal tumor and its risk

granulosa cell tumor | produces estrogen and risk of endometrial ca

mucinous cystdeno ca can cause

pseudomyxoma peritonei

dysgerminona is the female equi of

seminoma

in chorio ca, chorionic villi are

absent

other name for yolk sac tumor

endodermal sinus tumor

MC tumor in male infant

yolk sac tumor

symptom of fibroid

abn bleeding

endometritis Rx

gentamicin and clindamycin

Obesity risk of tumor

endometrial (androgen to estorgen in fat)

two tumors from breast stroma

fibroadenoma and phylloides tumor

lactational mastitis cause and Rx

aureus, dicloxacillin

gynecomastia causing drugs

ketoconazole, spironolcatone, cimetidine

yolk sac tumor marker

increased AFP

advantage of seminoma

excellent prognosis radio-sensitive

painful scrotal tumor

embryonal ca (hemarrhagic mass with necrosis)

seminoma marker

placental ALP

MC testicular cancer in older patients

testicular lymphoma

BPH vs tumor CC

BPH free PSA increased tumor total increased but free decreased Tumor prostatic acid phosphatase increased

two types of drugs for BPH

a1 antagonist terazocin and tamsulosin | 5a reductase inhibitor finasteride

clomiphene MOA

block estrogen receptor in HT and break negative feedback

mifepristone (RU-486) MOA

progesterone antagonist

two beta agonist to prevent labor

terbutaline and ritodrine

danazol MOA and indication

partial androgen agonist | endometriosis (causes hirsuitism)

flutamide for prostate ca is given with

leuprolide

minoxidil MOA

direct arteriololar vasodilator