Resp Patho Flashcards

1
Q

In obstructive pulmonary disorders, do inspiration or expiration require more force?

A

Expiration

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2
Q

Unifying symptom of obstructive pulmonary disorder

A

Dyspnea

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3
Q

Unifying sign of obstructive pulmonary disorder

A

Wheezing

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4
Q

3 most common obstructive pulmonary disorders

A

Asthma
Chronic bronchitis
emphysema

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5
Q

What 2 disorders fall under chronic obstructive pulmonary disease (COPD)?

A

Chronic bronchitis

Emphysema

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6
Q

What is tidal volume (TV) of a normal individual?

A

400-800 ml

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7
Q

How many breaths per minute is normal?

A

8-16

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8
Q

How is normal breathing described?

A

Rhythmic and effortless

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9
Q

What is when there is inadequate alveolar ventilation ?

A

Hypoventilation

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10
Q

What is when there is excessive alveolar ventilation?

A

Hyperventilation

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11
Q

When can a person enter a state of acidosis?

A

Hypoventilation

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12
Q

What is a reflex to clear airways? (larynx area)

A

Cough

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13
Q

What is selective bulbous enlargement at the end of a digit?

A

Clubbing

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14
Q

What are the 3 diseases that are obstruction from conditions in the wall of the lumen?

A

Asthma
Acute Bronchitis
Chronic Bronchitis

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15
Q

What disorder has a chronic, constant, inflammation in the airway?

A

Asthma

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16
Q

What is the major pathological feature of asthma?

A

Inflammation creating hyperresponsiveness of airway

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17
Q

What are the 2 types of asthma attacks?

A
Slow-onset acute
Hyperacute asthma (minutes to hours)
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18
Q

What separates acute bronchitis from pneumonia?

A

Bronchitis has clear chest films

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19
Q

What does the bacterial form of bronchitis have?

A

Productive cough with fever and sternal pain

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20
Q

What type cough does viral acute bronchitis usually have?

A

Non-productive

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21
Q

How long must a productive cough must continue to be classified as chronic bronchitis?

A

At least 3 months of the year for at least 2 consecutive years

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22
Q

What cells increase in chronic bronchitis?

A

Mucous glands and goblet cells in airway epithelium

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23
Q

What are individuals with chronic bronchitis referred to as?

A

Blue bloaters

24
Q

What is abnormal permanent enlargement of acini accompanied by destruction of alveolar walls without obvious fibrosis?

25
Why is emphysema an obstructive disorder?
Can't push air out due to loss of elastic tissue
26
What is primary emphysema?
Deficiency of enzyme alpha I-antitrypsin | Autosomal recessive
27
What does a person with emphysema look like?
Thin Tachypnea Increased chest diameter
28
What is an individual with emphysema described as ?
Pink Puffer
29
What are 5 obstructive disorders of the airway lumen?
``` Bronchiectasis Bronchiolitis Acute tracheobronchial obstruction Epiglottitis Croup syndrome ```
30
What is a persistent abnormal dilation of bronchi?
Bronchiectasis
31
What are the three types of bronchiectasis?
Cylindrical- Symmetrically dilated airways Saccular- Bronchi become large and balloon like Varicose- Deform bronchi overtime due to constrictions and dilations
32
What is Inflammatory obstruction of small airways or bronchioles?
Bronchiolitis
33
Is bronchiolitis more common in adults or children?
Children, but can occur in adults with chronic bronchitis
34
What is a blockage of trachea or bronchi?
Acute tracheobronchial obstruction
35
What lung is affected by acute tracheobronchial obstruction?
Right
36
What was epiglottitis historically caused by?
H. influenza type b
37
What age group does epiglottitis affected?
2-6
38
What signs are associated with epiglottitis?
High fever store throat inspiratory stridor severe respiratory distress
39
What is laryngotracheobronchitis?
Croup syndrome
40
What is the cause of croup?
Sub-glottic edema from infection
41
What is the most critical region with croup syndrome?
cricoid region
42
What syndrome has a seal-like barking cough?
Croup
43
What is ARDS?
Acute respiratory distress syndrome | Acute lung inflammation and diffuse alveolcapillary injury
44
What do all disorders that cause ARDS do?
acutely injure the alveolocapillary membrane and cause severe pulmonary edema
45
What is the hallmark of ARDS?
Increased capillary permeability
46
What is the main cell associated with ARDS?
Neutrophils
47
What are hyaline membranes (ARDS)?
Fibrosis areas that replace alveoli
48
What is FRC?
Functional reserve capacity
49
What happens to FRC with ARDS?
It is decreased
50
What is IRDS?
Infant respiratory distress syndrome
51
What is IRDS a disease of?
Hyaline membrane disease
52
What do ARDS and IRDS have in common?
Development of hyaline membranes
53
What population does IRDS occur in?
Premature infants (born before 30 weeks)
54
What is the primary cause of IRDS?
Lack of pulmonary surfactant
55
What causes hyaline membrane formation in IRDS?
leak of fluid into alveoli