Reproductive Normal Flashcards
What is the sac enclosing the testes?
Scrotum
What muscle wrinkles the skin of the scrotum?
Dartos muscle
What muscle elevates the testes?
Cremaster muscle
What do the two muscles of the scrotum help maintain?
Proper temperature
What are the two tunics of the testis deep to fascia?
Tunica vaginalis- outer layer (peritoneum)
Tunica albuginea- fibrous inner connective tissue
Why do testes need to be a lower temperature than the rest of the body?
Maturation of sperm cells
Extensions of the tunica albuginea inward divides the testes into _______.
Lobules
Each lobule in the testis contains ______ seminiferous tubules
1-4
What is the site of sperm production?
Seminiferous tubules
What receives sperm from the seminiferous tubules- maturation area
Rete testis
What transport sperm from rete testies to epididymis?
Efferent ductules
What is the long term for sperm maturation?
Epipdidymis
What abilities do sperm gain during maturation?
Swimming ability Acrosome development (egg penetration)
How long does sperm cells maturation take in the epididymis?
20 days to 3 months
How much sperm production can be stored in the epididymis.
6 months worth
What are interstitial cells b/w seminiferous tubules. Produce testosterone.
Leydig cells
What is a fibrous connective tissue sheath that moves through the inguinal canal. Encloses ductus defrens, nerves, blood vessels, lymphatics.
Spermatic cord
What is a single ventral column that surround the urethra- expands to form glans and bulb.
Corpus spongiosum
What is the name of paired dorsal columns that expands to form crura?
Corpus cavernosa
When the erectile tissue expands, what gets obstructed?
Venous outflow
What are the three regions of the penis?
Root- proximal internal
Shaft- medial external
Glans- distal cone shaped
What 2 things does the glans include?
External urethral opening
Prepuce (foreskin)
How long is the epididymis?
20 inches long
WHat are the three aspects of the epididymis?
Caput, corpus, cauda
head, body, tail
What aspect of the testis is the epididymis on?
Superior and posterolateral surface of testis
What carries sperm cells from epididymis to ejaculatory duct
Dusctus defrens (vas defrens)
WHat is the name of the terminal end of the ductus deferens?
Ampulla
How long is the ductus deferens?
18 inches long
What is formed by union of amuplla of vas deferenes and duct of seminal vesicle. Passes through prostate and into prostatic urethra.
Ejaculatory duct
What conveys semen to body surface and also has urinary functions.
Urethra
What two things are in semen?
Seminal fluid and sperm
What do male accessory glands produce?
Secrete substances that form seminal fluid
Where are seminal vesicles located?
Posterior to bladder
How much of the seminal fluid comes from the seminal vesicles?
60 %
Alkaline secretion from the seminal vesicles do what?
Neutralize pH in female’s body
Why does seminal fluid contain fructose?
Energy source for the mitochondria
Where are the mitochondria located in sperm?
Mid part, helps to power the tail
What encircles the urethra and contains the ejaculatory duct. Secretions make up 33% of seminal fluid
Prostate gland
Seminal fluid from the prostate gland gives enzymes for what?
Sperm activation (enables enzymes to chew through outside of the egg)
What is the job of the bulbourethral glands (cowper’s glands)
Alkaline mucus
What does the alkaline mucus from the bulbourethral glands do?
Neutralize the pH in the male’s urethra
__________ is a parasympathetic spinal reflex whereas ____________ is sympathetic.
Erection- parasympathetic
Ejaculation- sympathetic
The release of what causes vasodilation and engorgement?
NO (nitrous oxide)
What prevents black flow of semen to the bladder?
Internal urinary sphincter
What does type A daughter cell do?
Stays at peripheral of seminiferious tubule
Where does the type B daughter cell go?
Moves toward lumen and differenciates into primary spermatocyte
What undergoes meiosis I and produces two secondary spermatocytes?
Primary spermatocytes
What is the process by which spermatids become sperm?
Sperminogenesis
What undergoes meiosis II and produces two spermatids each?
Secondary spermatocytes
What 4 things happen during spermiogenesis?
Excess cytoplasm lost
Midpiece production (mitochondria)
Flagellum produced
Acrosome produced
What can lumenal sperm do?
Basically nothing- need to go through maturation steps to be able to swim or penetrate ovum
What do sustentacular (Sertoli) cells do?
Wrap around cells in development and support and nourish them
What forms the blood-testis barrier?
Tight junctions between sustentacular cells
WHat does the basal compartment contain?
Spermatogonia (stem cells, Type A, Type B)
What 4 things compose the brain-testicular axis?
GnRH, LH, FSH, testes
What causes Sertoli cells to release ABP (androgen binding protein)
FSH
What hormone cuases Leydig cells (interstitial cells) to release testosterone?
LH
What is released by Sertoli cells when sperm count is too high?
Inhibin
What does inhibin do?
Inhibits FSH, but doesn’t inhibit testosterone
What does testosterone do?
Develop and maintain accessory sex organs and secondary sex characteristics
Increased BMR
Libido (male and female)
What are the two tunics of the ovaries?
Geminal epithelium- outer, simple cubodial
Tunica albuginea- inner- fibrous connective tissue
What contains developing oocyte?
Ovarian follicles (contain many layers)
What stage are the follicles in when a girl is born?
Primordial (primitive)
What are the stages of the oocyte/ follicle?
Primoridial (primitive) Primary Secondary Graafian (mature) Corpus Luteum Corpus albicans
What ends from ovary to uterus and transports the ovum?
Uterine tubes (fallopian tubes, oviducts)
What are the three parts of the uterine tubes?
Isthmus
Ampulla
Infundibulum
What is the constricted region of the uterine tubes near the uterus?
Isthmus
What is the expanded region around the ovary in the uterine tubes. Most common site of fertilization
Ampulla
What is the distal end of the fallopian where it comes in contact with the ovary.
Infundibulum
What are the two layers of the fallopian tube?
Mucosa- ciliated simple columnar
Muscularis- peristalsis
What are the three regions of the uterus?
Fundus
Body
Cervix
Uterus is ______ to the bladder.
Posterior
What part of the uterus sticks over the bladder?
Fundus
What are the two layers of the endometrium?
Stratum functionale (superior) Stratum basale
What layer is shed during menstruation?
Stratum functionale
What types arteries serve the stratum functionale?
Spiral arteries
What type arteries serve the stratum basale?
Straight arteries
If a women doesn’t get pregnant, what happens to spiral arteries?
Get cut off and endometrium is shed
What is the thick middle smooth muscle layer of the uterus?
Myometrium
What makes up the outer visceral peritoneum of the uterus?
Perimetrium
What is the muscular tube from cervix to exterior?
Vagina
What are the two regions of the vagina?
Fornix- area surrounding cervix
Vaginal orifice- distal opening
What are the three layers of the vagina?
Mucosa- non-keratinized stratified squamous
Muscularis- middle smooth muscle layer
Adventitia- outer connective tissue layer
What is adipose pad overlying the pubic bone in females?
Mons pubis
What is the outermost hair covered skin folds?
Labia majora
What are the inner hairless skin folds that line the vestibule?
Labia minora
What is inside the labia minora?
Vestibule
From superior to inferior what are in the vestibule?
Clitoris
Urethral orifice
Vaginal orifice
Vestibular (Bartholin’s) glands
What do the vestibular glands do in the female?
Keep the area moistened
WHat divides by mitosis to form primary oocytes?
Oogonia (stem cells)
What begin meiosis I and arrest at prophase I until puberty?
Primary oocytes
One oogonia in a female becomes ____ oocyte.
One
When does the secondary oocyte arrest?
Metaphase II
When does meiosis finish?
At fertilization
Produces ovum and second polar body
What days during the ovulation cycle does the follicular phase happen?
Days 1-13
During the follicular phase what does the primary follicle turn into?
Secondary follicle
Follicular cells stratify into granulosa cells
What forms around follicle to produce androgens- converted to estrogens (follicular phase). Responds to lutenizing hormone
Theca folliculi
What is a glycoprotein coat on the outside of the oocyte when you have a secondary follicle. Prevents any sperm from getting into the egg. Species specificity
Zona pellucida
How many sperm cells can fertilize an egg with no zona pellucida?
As many as fit
What does a secondary follicle become?
Graffian
What triggers ovulation?
LH surge
Up to day 14 what is the dominate hormone?
Estrogen
After day 15 what is the dominante hormone?
Progesterone
Where is the luteal phase?
Day 15-28
What does the corpus luteum degenerate to?
Cospus albicans
What does the corpus luteum secrete?
Progesterone
WHat do the corona radiata?
Go with the secondary oocyte at time of ovulations
What stimulates the synthesis and release of FSH and LH on Day 1 of the ovarian cycle?
rising GnRH
What causes thecal cells to produce androgens?
LH
What causes granulosa cells to convert androgens to estrogens?
FSH
HIgh _____ levels produce positive feedback on production of LH and FSH.
estrogen
What do high levels of progesterone prevent?
Prevent ovulation
When LH levels drop, what distintegrates?
Corpus luteum
What days is the menstrual phase of the uterine cycle?
Days 1-5
What happens during the menstrual phase of the uterine cycle?
stratum functionale is shed
During the menstrual cycle, what days does the proliferative phase?
6-14
During which phase of the menstrual cycle do rising estrogen rebuild endometrium?
Proliferative phase
During what phase of the menstrual cycle do rising progesterone prepare uterus for implantation?
secretory phase: Days 15-28
What hormone develops and maintains accessory sex organs and secondary sex characteristics as well as metabolic effects. Effects calcium metabolism
Estrogen
What prepares breasts for lactation?
Progesterone