Reproductive System Flashcards
Pathway of sperm through reproductive system
Seminiferous tubules -> epididymis -> vas deferns -> ejaculatory duct -> urethra -> penis
Sperm structure
Head, midpiece, flagellum
Sperm midpiece is filled with
Mitochondria for movement energy
Sperm head is covered by
Acrosome for penetrating ovum
Sperm is nourished by
Sertoli cells
Interstitial cells of Leydig
Secrete testosterone
Scrotum
External pouch that maintains lower temperature for spermatogenesis
Seminal vesicles
Nourish sperm with fructose
Prostate gland and seminal vesicles
Give fluid mildly alkaline character
Spermatogonia
Diploid stem cells that become sperm
Ovaries
Produce estrogen and progesterone
Cervix
Connects to vaginal canal
Menarche
First menstrual cycle
GnRH is restricted during puberty by
Hypothalamus
GnRH causes
Release of FSH and LH, leading to secondary sex characterestics
In males, FSH
Triggers spermatogenesis by stimulating sertoli cells
In males, LH
Produces testosterone
In females, FSH
Stimulates development of ovarian follicles
In females, LH
Causes ovulation
Menstrual cycle
Follicular phase -> ovulation -> luteal phase -> menstruation/pregnancy
Follicular phase
GnRH secretion stimulates FSH and LH secretion, which promotes follicle development
Ovulation
Stimulated by LH spike, triggered when estrogen levels reach a threshold, increased FSH, LH, GnRH
Luteal phase
LH forms corpus luteum, which secretes of progesterone that maintains uterine lining
hCG
Maintains corpus luteum
Cell cycle stages
G1, S, G2, M
Prophase
Chromosomes condense, nuclear membrane dissolves, nucleoli disappear, centrioles migrate to opposite poles, spindle forms
Metaphase
Chromosomes gather align at metaphase plate
Anaphase
Sister chromosomes separate
Telophase
Chromosomes decondense, nuclear membrane forms, nucleoli reappear, spindle disappears, cell divides
Upon ovulation, oocyte is released to the
Abdominal cavity
Sperm development steps
Spermatogonium -> 1’ spermatocyte -> 2’ spermatocyte -> spermatid -> spermatozoa
Estrogen leads to thickening of
Endometrium
Progesterone
Maintenance of endometrium
Progesterone is secreted by
Corpus luteum
Ovulation features
Egg is released from follicle into peritoneal cavity
Luteal phase features
Corpus luteum produces progesterone to maintain endometrium
Follicular phase features
Follicles mature
S stage
DNA is replicated, chromatids held together at centromere
Sister chromatids
Copies of same DNA hold together at the centromere
Prophase I of meiosis
Homologous chromosomes exchange genetic material via crossing over