Cardiovascular System Flashcards
Cardiovascular system consists of
Four-chambered heart, blood vessels, and blood
Right side of the heart accepts
Deoxygenated blood and moves it to the lungs
Left side of the heart
Receives oxygenated blood from the lungs and forces it out to the body
Two pumps
Pulmonary circulation and systemic circrulation
Pulmonary circulation
Right side of the heart accepts deoxygenated blood and moves it to lungs by way of pulmonary arteries
Systemic circulation
Left side of the heart receives oxygenated blood from the lungs by way of pulmonary veins and forces it out to the body through the aorta
More muscular side of heart
Left side
Atria
Thin-walled structures that receive blood from the venae cavae or pulmonary veins
Venae cavae
Deoxygenated blood enters right heart
Pulmonary veins
Oxygenated blood enters left heart
Atrioventricular valves
Separate atria from ventricles
Semilunar valve
Ventricles are separated from vasculature
Tricuspid valve
Valve between right atrium and right ventricle
Bicuspid valve
Valve between left atrium and left ventricle
Pulmonary valve
Separates right ventricle from pulmonary circulation
Aortic valve
Separates left ventricle from aorta
Pulmonary valve and aortic valves are
Semilunar valves
Pathway of electrical conduction in heart
SA node -> AV node -> bundle of His -> Purkinje fibers
Systole
Ventricule contracts, AV valves close, blood is pumped out
Diastole
Ventricles relax, semilunar valves close, blood from atria fills ventricles
Cardiac output
Total blood volume pumped by a ventricle in a minute
CO equation
CO = HR X SV
Stroke volume
Volume of blood pumped per beat
Arteries
Carry blood away from the heart
Vagus nerve
Slows down heart rate, provide parasympathetic signals
What property of the large arteries help vessels maintain sufficient pressure?
Highly muscular and elastic
Veins
Bring blood to heart
Capillaries
Thin wall, easy diffusion of gases
Endothelial cells
Facilitate formation of blood clots to stop bleeding when damage occurs
Vein characteristics
Inelastic, thin-walled, can stretch for large quantities of blood
Portal system
Blood passes through two capillary beds before returning to the heart
Hepatic portal system
Gut capillary bed -> liver capillary bed
Hypophyseal portal system
Hypothalamus capillary bed -> anterior pituitary capillary bed
Renal portal system
Glomerulus -> vasa recta
Cellular portion of blood three types
Erythrocytes, leukocytes, platelets
All blood cells are formed from
Hematopoietic stem cells from bone marrow
Granulocytes
Contain granules that are toxic to invading microbes
Granulocytes are involved in
Inflammatory reactions, allergies, destruction of bacteria and parasites
Agranulocytes
Lymphocytes and monocytes
Lymphocytes are involved in
Specific immune response
Monocytes
Phagocytize foreign matter such as bacteria
When monocytes enter an organ, they are renamed
Macrophages
Universal recipient
Type AB
Universal donor
Type O
An individual with B+ blood could receive
B+, B-, O+, O-
An individual with B+ blood could donate to
B+, AB+
Blood pressure is measured by
Sphygmomanometer
Largest drop in blood pressure occurs across
Arterioles, because capillaries are thin walled and unable to withstand pressure
Low blood pressure releaes
Aldosterone and ADH
ADH blood pressure
Antidiuretic hormone increases blood volume and pressure and dilutes blood
Aldosterone blood pressure
Increases water and sodium resorption, increasing blood volume and pressure
Cause of a right shift of the oxyhemoglobin curve
Exercise, increased CO2, increased temperature, lower pH
Left shift to the oxyhemoglobin curve
Decreased CO2, higher pH, decreased temperature, decreased 2,3-BPG
A and B alleles are
Codominant
O alleles are
Recessive
Bohr effect
Increased CO2 -> increased [H+] -> reduce hemoglobin affinity for oxygen -> shift right
Starling forces
Balance of hydrostatic and osmotic pressure
Edema
Excess of fluid in tissues
Coagulation
Activation cascade forms thrombin, which converts fibrinogen to fibrin
Hematocrit
Percentage of red blood cells in blood
Which blood cell contains nuclei
Leukocytes
Valve that prevents backflow in right atrium
Tricuspid valve
Valve that prevents backflow in right ventricle
Pulmonary valve
Valve that prevents backflow in left atrium
Bicuspid valve
Valve that prevents backflow in left ventricle
Aortic valve